Immunotherapy News and Research

Latest Immunotherapy News and Research

Blocking TIM-3 checkpoint molecule promotes antitumor immune response in diffuse intrinsic stem glioma

Researchers from Cima and the Clínica Universidad de Navarra, together with the international cooperative group Diffuse Midline Glioma (DMG-ACT), have confirmed that blocking an immune checkpoint molecule reduces the tumor and prolongs survival in animal models of the most aggressive childhood cancer. This research, carried out at the Cancer Center Clínica Universidad de Navarra, shows that inhibition of TIM-3 promotes the immune memory of diffuse intrinsic stem glioma (DIPG) and improves the prognosis of the disease.

9 Oct 2023

Researchers explore immunomodulating targets for improving glioblastoma therapies

Researchers have delved into the intricate heterogeneity of glioblastoma, a notoriously aggressive brain tumor, using advanced single-cell RNA sequencing and innovative zebrafish avatars. Their findings spotlighted the LGALS1 gene's role in immunosuppression and suggested potential therapeutic avenues for personalized GBM treatment.

8 Oct 2023

Breakthrough research could lead to more effective immunotherapies for bowel cancer

Every year, over 15,500 Australians are diagnosed with bowel cancer, and it is the second leading cause of cancer deaths in the country.

6 Oct 2023

Researchers discover a vulnerability in immunotherapy-resistant triple-negative breast cancer

Researchers at Vanderbilt-Ingram Cancer Center have discovered a druggable target on natural killer cells that could potentially trigger a therapeutic response in patients with immunotherapy-resistant, triple-negative breast cancer.

5 Oct 2023

New computational method improves analysis of single-cell transcriptomic data

Researchers at Memorial Sloan Kettering Cancer Center (MSK) have developed a new open-source computational method, dubbed Spectra, which improves the analysis of single-cell transcriptomic data.

5 Oct 2023

Unlocking the future of cancer care: Overcoming challenges in personalized neoantigen vaccine development

Challenges associated with the development and design of neoantigen cancer vaccines.

5 Oct 2023

Is ChatGPT ready to be your next medical advisor?

Vanderbilt University researchers explored ChatGPT's potential in medical information provision to professionals and patients. While showing promise in delivering accurate, comprehensive medical insights, the need for continuous algorithm refinement and better source discernment were highlighted to fully harness ChatGPT's potential.

3 Oct 2023

Metabolism-targeting drug could offer new hope for cancer-related fatigue

Cancer-related fatigue (CRF) is a debilitating yet all-too-common condition, which can severely affect quality of life for patients undergoing treatment.

3 Oct 2023

Research opens the door for better use of people's own immune system T cells to fight cancer

Using laboratory-grown cells from humans and genetically engineered mice, scientists at Johns Hopkins Medicine say they have evidence that modifying a specific protein in immune white blood cells known as CD8+ T cells can make the cells more robust, potentially opening the door for better use of people's own immune system T cells to fight cancer.

3 Oct 2023

Monocyte-derived macrophages play a crucial role in liver regeneration

The liver is a vital organ that plays a role in many essential functions, including digestion, detoxification, and metabolism.

29 Sep 2023

Extending FDA-approved cancer drug indications requires high patient numbers, study finds

Number of patient participants needed for secondary approval of a new cancer drug.

29 Sep 2023

Researchers unlock new insights into hard-to-treat neuroendocrine tumors

Researchers at Boston Medical Center and Dana-Farber Cancer Institute conducted one of the first-ever analyses of neuroendocrine tumors (NETs) at single cell resolution, unlocking new insights into this rare and often hard-to-treat cancer.

28 Sep 2023

Neoadjuvant immunotherapy shows promise in multiple cancer types

Treating cancer with immunotherapies known as an immune checkpoint blockade (ICB) prior to surgery (so-called neoadjuvant immunotherapy) has been a rapidly growing area of research, but the scientific community is just scratching the surface of what is possible, according to a review article co-authored by several current and former investigators from the Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Kimmel Cancer Center.

28 Sep 2023

Study details the key role played by neutrophils in ensuring survival of brain cancers

A Ludwig Cancer Research study has for the first time exhaustively analyzed immune cells known as neutrophils that reside in brain tumors, including gliomas, which develop in the brain itself, and cancers that spread there from the lung, breast and skin.

27 Sep 2023

New form of cellular immunotherapy shows promise against brain tumors in mice

Scientists from the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim (UMM) successfully tested a new form of cellular immunotherapy against brain tumors in mice for the first time.

26 Sep 2023

$45M awarded to develop sense-and-respond implant technology for cancer treatment

The Advanced Research Projects Agency for Health (ARPA-H) has awarded $45 million to rapidly develop sense-and-respond implant technology that could slash U.S. cancer-related deaths by more than 50%.

26 Sep 2023

Radiation therapy combined with two types of immunotherapy could be effective against cold tumors

Researchers at Weill Cornell Medicine have discovered that radiation therapy combined with two types of immunotherapy - one that boosts T cells, and another that boosts dendritic cells - can control tumors in preclinical models of triple negative breast cancer, a cancer type that's typically resistant to immunotherapy alone.

25 Sep 2023

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Tumor vaccines can help the body fight cancer. These vaccines alert the patient's immune system to proteins that are carrying cancer-typical alterations.

22 Sep 2023

Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

An international clinical trial exploring a new way to treat rare and aggressive gynaecological cancers has launched in Melbourne.

21 Sep 2023

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

A Ludwig Cancer Research study has shown that combining adoptive T cell therapy (ACT) with an innovative, personalized cancer vaccine under development at the Lausanne Branch of the Ludwig Institute for Cancer Research can benefit patients with late-stage, drug-resistant ovarian cancer.

21 Sep 2023

Immunotherapy News and Research

Latest Immunotherapy News and Research

Blocking TIM-3 checkpoint molecule promotes antitumor immune response in diffuse intrinsic stem glioma

Researchers explore immunomodulating targets for improving glioblastoma therapies

Breakthrough research could lead to more effective immunotherapies for bowel cancer

Researchers discover a vulnerability in immunotherapy-resistant triple-negative breast cancer

New computational method improves analysis of single-cell transcriptomic data

Unlocking the future of cancer care: Overcoming challenges in personalized neoantigen vaccine development

Is ChatGPT ready to be your next medical advisor?

Metabolism-targeting drug could offer new hope for cancer-related fatigue

Research opens the door for better use of people's own immune system T cells to fight cancer

Monocyte-derived macrophages play a crucial role in liver regeneration

Extending FDA-approved cancer drug indications requires high patient numbers, study finds

Researchers unlock new insights into hard-to-treat neuroendocrine tumors

Neoadjuvant immunotherapy shows promise in multiple cancer types

Study details the key role played by neutrophils in ensuring survival of brain cancers

New form of cellular immunotherapy shows promise against brain tumors in mice

$45M awarded to develop sense-and-respond implant technology for cancer treatment

Radiation therapy combined with two types of immunotherapy could be effective against cold tumors

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

eBook: Cell-based technologies in drug discovery and Immunotherapy eBook

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Scalable, Smart, and Accessible: The Future of Lab Automation

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Immunotherapy News and Research

Latest Immunotherapy News and Research

eBook: Cell-based technologies in drug discovery and Immunotherapy eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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