Immunotherapy News and Research

Latest Immunotherapy News and Research

New cooling strategy could prevent the growth of glioblastoma

Cooling brain tumor cells to stop them from dividing without killing healthy cells extended the survival of glioblastoma (GBM) animal models dramatically in a study led by a UT Southwestern resident.

12 Jan 2023

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

Immune checkpoint inhibitors are important medications that boost the immune system's response against various cancers, but some patients' cancer cells are unaffected by the drugs or develop resistance during treatment.

12 Jan 2023

Experts propose solutions to address racial disparities affecting people with allergic conditions

In February 2022, the American College of Allergy, Asthma and Immunology convened experts in atopic dermatitis (AD) and food allergy to examine the issue of racial disparities affecting people with these conditions.

12 Jan 2023

Immunotherapy prior to surgery strikingly effective for patients with colorectal cancer

New research in the January 2023 issue of JNCCN-;Journal of the National Comprehensive Cancer Network finds that immunotherapy from immune checkpoint (PD-1) inhibitors prior to surgery was strikingly effective for patients with localized mismatch repair-deficient or microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC).

12 Jan 2023

CAR T cell therapy may enhance the effectiveness of surgery for solid tumors

CAR T cell therapy, an approach which reprograms patients' own immune cells to attack their blood cancers, may enhance the effectiveness of surgery for solid tumors, according to a preclinical study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

11 Jan 2023

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Severe inflammation weakens the body's ability to kill cancerous blood cells in people with acute myeloid leukemia (AML), a new study shows.

11 Jan 2023

Simple method increases the efficacy of T cell therapy by cytokine conjugation

The recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer therapy) and other immune cells are obtained from patients, activated and multiplied outside the body, and infused in larger numbers back into the blood circulation to help fight cancers.

11 Jan 2023

Drug combination elicits efficacious anti-tumor immunity against immunotherapy-resistant cancers

Immunotherapy is a way of treating cancer by reprogramming the patient's immune system to attack their tumor.

10 Jan 2023

Novel T cell receptor therapy shows early promise for treating solid tumors

Afamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A4 cancer antigen, achieved clinically significant results for patients with multiple solid tumor types in a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

9 Jan 2023

Is universal coronavirus immunity possible?

In a recent study posted to the bioRxiv* preprint server, researchers at Columbia University characterized reciprocal and non-reciprocal T-cell responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

8 Jan 2023

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

A new research paper was published in Oncotarget's Volume 13 on December 20, 2022, entitled, "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression."

6 Jan 2023

Study details the “immunometabolic editing” mechanism of tumor evolution

A Ludwig Cancer Research study has discovered that the immune system's surveillance of cancer can itself induce metabolic adaptations in the cells of early-stage tumors that simultaneously promote their growth and equip them to suppress lethal immune responses.

5 Jan 2023

New dual-action, cancer-killing vaccine tested in an advanced mouse model of glioblastoma

Scientists are harnessing a new way to turn cancer cells into potent, anti-cancer agents. In the latest work from the lab of Khalid Shah, MS, PhD, at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, investigators have developed a new cell therapy approach to eliminate established tumors and induce long-term immunity, training the immune system so that it can prevent cancer from recurring.

4 Jan 2023

Immunotherapy News and Research

Latest Immunotherapy News and Research

New cooling strategy could prevent the growth of glioblastoma

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

Experts propose solutions to address racial disparities affecting people with allergic conditions

Immunotherapy prior to surgery strikingly effective for patients with colorectal cancer

CAR T cell therapy may enhance the effectiveness of surgery for solid tumors

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Simple method increases the efficacy of T cell therapy by cytokine conjugation

Drug combination elicits efficacious anti-tumor immunity against immunotherapy-resistant cancers

Novel T cell receptor therapy shows early promise for treating solid tumors

Is universal coronavirus immunity possible?

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

Study details the “immunometabolic editing” mechanism of tumor evolution

New dual-action, cancer-killing vaccine tested in an advanced mouse model of glioblastoma

Distinct genomic patterns of malignant peripheral nerve sheath tumors may help with early diagnosis

Novel triple immunotherapy combination improves anti-tumor responses in preclinical models of pancreatic cancer

Novel approach may prevent antibodies from triggering immune rejection of transplant cells

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

NCI-led clinical trial results in the first approval of a treatment for advanced alveolar soft part sarcoma

Wafer-thin device could drastically alter the course of treatment for Type 1 diabetes

High ammonia levels lead to fewer T cells and immunotherapy resistance in colorectal cancer

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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