Immunotherapy News and Research

Latest Immunotherapy News and Research

Cancer-related fatigue contributes to balance problems following exposure to chemotherapy for breast cancer

For many women who have undergone chemotherapy for breast cancer, cancer-related fatigue (CRF) is a persistent side effect – and one that contributes to ongoing balance problems, suggests a paper in Rehabilitation Oncology, official journal of APTA Oncology, an academy of the American Physical Therapy Association (APTA).

15 Aug 2022

People with blood-related cancers more likely to experience COVID breakthrough infections

Individuals with blood-related cancers are more likely to experience a COVID-19 infection even after being vaccinated, a University of Kansas Cancer Center study has found.

12 Aug 2022

OICR funding to help five research projects take the next step toward advancing cancer care

Five Ontario-based research projects will take the next step toward advancing cancer care in the province thanks to funding from the Ontario Institute for Cancer Research (OICR).

11 Aug 2022

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Stimulator of interferon genes, or STING, helps regulate immune activation. Thus, drugs that activate STING are being tested as a form of cancer immunotherapy and for treating certain infections.

11 Aug 2022

Research may lead the way to a simpler treatment for cancer

Sometimes too much of a good thing is not good at all. Inhibiting the function of the PD-1 protein, which blocks immune function, has shown high therapeutic efficacy in cancer immunotherapy.

10 Aug 2022

Less than half of the YouTube videos on allergic rhinitis provide useful information, study finds

Want to build a spice rack for your kitchen? Pull up a YouTube video to see how it might be done. Got allergic rhinitis (hay fever) symptoms that just won't quit? Don't do a random YouTube search because the information you find there has a good chance of being inaccurate.

10 Aug 2022

Researchers synthesize a small molecule that can be used to treat a range of cancers

Researchers at Tel Aviv University and the University of Lisbon have jointly identified and synthesized a small molecule that could be a more accessible and effective alternative to an antibody that is successfully used to treat a range of cancers.

8 Aug 2022

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Young people who received doses of tisagenlecleucel, a chimeric antigen receptor T cell (CAR-T) therapy, at the higher end of the FDA-approved dosing range had significantly better survival rates at one year compared with those who received lower doses within this range, according to research published today in Blood Advances.

8 Aug 2022

First Phase II study of immunotherapy combined with curative radiotherapy for unresectable locally advanced NSCLC

Researchers from Japan today reported that the first phase II study to evaluate the efficacy and safety of durvalumab and concurrent curative radiation therapy for PD-L1-positive unresectable locally advanced non-small cell lung cancer without chemotherapy met its primary endpoint with tolerable adverse reactions.

8 Aug 2022

Consolidation PD-(L)1 inhibition following concurrent chemoradiation for unresectable stage III NSCLC improves survival

Following concurrent chemoradiation for unresectable stage III non-small cell lung cancer, both nivolumab alone and nivolumab and ipilimumab combined demonstrated improved 18- month progression-free survival compared with historical controls despite a shortened interval (6 months) of treatment.

8 Aug 2022

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Researchers from Spain have identified an immune expression signature in surgical specimens associated with disease progression for non-complete pathological responders patients treated with neo adjuvant chemo-immunotherapy, which could help the follow-up and therapeutic management of these high-risk patients.

8 Aug 2022

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

A study presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna disclosed the clinical-relevant intertumoral heterogeneity of non-small cell lung cancer (NSCLC) driven by MET exon 14 skipping.

8 Aug 2022

Implantable mechanotherapeutic drug delivery platform helps overcome host immune response

Implantable devices that release insulin into the body hold promise as an alternative way to treat diabetes without insulin injections or cannula insertions. However, one obstacle that has prevented their use so far is that the immune system attacks them after implantation, forming a thick layer of scar tissue that blocks insulin release.

8 Aug 2022

Terminally exhausted T cells may remain competent for transcription, researchers say

During a battle with cancer, T cells can become exhausted and are no longer able to function properly. The early phase of exhaustion can sometimes be reversed with immunotherapy drugs, but once T cells become too exhausted, it had been thought that this state was irreversible. However, new insights from University of Pittsburgh and UPMC researchers suggest that even the most fatigued T cells can be revived.

8 Aug 2022

Novel fusion protein drug for Alzheimer’s disease circumvents the neurotoxic inflammatory side effects

Although Aduhelm, a monoclonal antibody targeting amyloid beta (Aβ), recently became the first US FDA approved drug for Alzheimer's disease (AD) based on its ability to decrease Aβ plaque burden in AD patients, its effect on cognitive improvement is still controversial.

4 Aug 2022

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

Investigators from Cedars-Sinai Cancer have identified genetic signatures that could predict whether tumors in patients with bladder and other cancers will respond to immunotherapy.

3 Aug 2022

UVA researchers receive $15 million from LeDucq Foundation to advance understanding of atherosclerosis

The Boston-based LeDucq Foundation has awarded $15 million to researchers at UVA Health and their collaborators to advance our understanding of atherosclerosis, or hardening of the arteries, and find better ways to treat it.

3 Aug 2022

LJI acquires Carterra LSA instrument to enhance antibody screening and characterization efforts

Carterra, Inc., the world leader in innovative technologies enabling high-throughput biology, and La Jolla Institute for Immunology, a globally recognized non-profit research organization dedicated to understanding the power of the immune system to promote human health, announced today that LJI has acquired a Carterra LSA instrument to enhance its antibody screening and characterization work.

2 Aug 2022

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

Wake Forest Institute for Regenerative Medicine researchers are using a tumor organoid system to examine the effects of metabolites secreted by bacteria on a specialized immunotherapy – immune checkpoint blockage, a promising cancer treatment development – to determine why some patients don't respond or develop a resistance to the treatment over time.

29 Jul 2022

Novel targeted therapy may be an effective treatment option for neuroblastoma

New research from VCU Massey Cancer Center -; published Thursday in Cell Reports -; demonstrated that a novel targeted therapy could be an effective treatment option for a deadly pediatric cancer known as neuroblastoma.

28 Jul 2022

Immunotherapy News and Research

Latest Immunotherapy News and Research

Cancer-related fatigue contributes to balance problems following exposure to chemotherapy for breast cancer

People with blood-related cancers more likely to experience COVID breakthrough infections

OICR funding to help five research projects take the next step toward advancing cancer care

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Research may lead the way to a simpler treatment for cancer

Less than half of the YouTube videos on allergic rhinitis provide useful information, study finds

Researchers synthesize a small molecule that can be used to treat a range of cancers

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

First Phase II study of immunotherapy combined with curative radiotherapy for unresectable locally advanced NSCLC

Consolidation PD-(L)1 inhibition following concurrent chemoradiation for unresectable stage III NSCLC improves survival

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

Implantable mechanotherapeutic drug delivery platform helps overcome host immune response

Terminally exhausted T cells may remain competent for transcription, researchers say

Novel fusion protein drug for Alzheimer’s disease circumvents the neurotoxic inflammatory side effects

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

UVA researchers receive $15 million from LeDucq Foundation to advance understanding of atherosclerosis

LJI acquires Carterra LSA instrument to enhance antibody screening and characterization efforts

Researchers use a tumor organoid system to examine bacterial effects on immunotherapy

Novel targeted therapy may be an effective treatment option for neuroblastoma

eBook: The Ultimate Guide to Successful Immunofluorescence eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Immunotherapy News and Research

Latest Immunotherapy News and Research

eBook: The Ultimate Guide to Successful Immunofluorescence eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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