Immunotherapy News and Research

Latest Immunotherapy News and Research

'Crown-like structures' surrounding breast tumors could hinder treatment response, study finds

A new study from the University of Southampton has discovered that 'crown-like structures' surrounding breast tumors in overweight and obese patients could hinder their response to therapy.

24 May 2022

Penn Medicine and CHOP announce plans with Costa Rica's CCSS for CAR T research

Penn Medicine and Children's Hospital of Philadelphia, who together pioneered the research and development of the world's first personalized cellular therapy for cancer -; also known as CAR T cell therapy -; have announced plans with Costa Rica's CCSS, or the Caja Costarricense de Seguro Social (Social Security Program), to facilitate CAR T research in Costa Rica.

23 May 2022

Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients

A blood-based tumor biomarker can predict the benefit of immunotherapy to patients with non-small cell lung cancer, according to a study published in Nature Medicine.

20 May 2022

NIH team documents various types of neuropathy after COVID vaccination

In a recent study posted to the medRxiv* preprint server, researchers investigated if coronavirus disease 2019 (COVID-19) vaccination could result in neuropathic symptoms.

19 May 2022

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Investigators from Rutgers Cancer Institute of New Jersey, New Jersey's only National Cancer Institute- Designated Comprehensive Cancer Center, led a collaborative study to examine the patterns of druggable oncogenic fusions in colon cancer specimens including microsatellite-stable and unstable (MSI) tumors.

19 May 2022

Using 'off-the-shelf' engineered stem cell based therapy for treating glioblastomas post-surgery

Glioblastomas (GBMs) are highly aggressive cancerous tumors of the brain and spinal cord. Brain cancers like GBM are challenging to treat because many cancer therapeutics cannot pass through the blood-brain barrier, and more than 90 percent of GBM tumors return after being surgically removed, despite surgery and subsequent chemo- and radiation therapy being the most successful way to treat the disease.

19 May 2022

Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma

A research team at LKS Faculty of Medicine, The University of Hong Kong discovered that exosomes derived from γδ-T cells (γδ-T-Exos) synergised with radiotherapy can control nasopharyngeal carcinoma (NPC) by overcoming the radioresistance of NPC cancer stem cells (CSCs) and preserve their tumor-killing and T cell-promoting activities in the immunosuppressive NPC microenvironment.

18 May 2022

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Imugene Limited, a clinical stage immuno-oncology company, and City of Hope, one of the largest cancer research and treatment organizations in the United States, today announced that the first patient was dosed in a Phase 1 clinical trial evaluating the safety of novel cancer-killing virus CF33-hNIS VAXINIA when used in people with advanced solid tumors.

18 May 2022

Immunotherapy combined with chemoradiation and surgery could help treat nonmetastatic gastroesophageal cancer

Immunotherapy has transformed treatment for patients with stage 4 metastatic esophageal and gastric cancers. In patients with these malignancies, immunotherapy has been shown to prolong survival when patients' tumors exhibit a high expression of an immune-related protein called PD-L1.

16 May 2022

Immunotherapy after bladder cancer surgery helps reduce cancer recurrence

Immunotherapy after surgery helped reduce cancer recurrence in patients with urothelial cancer of the bladder or other sites in the urinary tract that had invaded the muscle and therefore posed a high risk for recurrence, according to clinical trial results presented at the American Urological Association annual meeting in May.

15 May 2022

Antibiotics disrupt the immune system in the gut leading to fungal infection

Patients prescribed antibiotics in hospital are more likely to get fungal infections because of disruption to the immune system in the gut, according to a new study from the University of Birmingham and National Institutes of Health.

13 May 2022

Penn study finds low uptake of first mutation-targeted bladder cancer drug

The first bladder cancer drug targeting a cancer-driving gene mutation has been used relatively little despite its clear efficacy in a clinical trial, suggests a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

12 May 2022

Study could provide a new approach to treating metastatic triple negative breast cancer

Research from the University of Michigan Rogel Cancer Center could provide a new approach to treating an aggressive form of breast cancer.

12 May 2022

Study modeling tumor evolution reveals a central tradeoff that could be exploited for cancer treatment

Though the mutations accumulated by cancer cells occur more or less randomly, certain regions of genes essential to cancer growth appear to be more frequently mutated than others in established tumors.

11 May 2022

World's first Focused Ultrasound Cancer Immunotherapy Center could revolutionize cancer care

UVA Health and the Charlottesville-based Focused Ultrasound Foundation today announced the launch of the Focused Ultrasound Cancer Immunotherapy Center, the world's first center dedicated specifically to advancing a focused ultrasound and cancer immunotherapy treatment approach that could revolutionize 21st-century cancer care.

11 May 2022

New guideline provides guidance on the use of radiation therapy to treat patients with brain metastases

A new clinical guideline from the American Society for Radiation Oncology provides guidance on the use of radiation therapy to treat patients with brain metastases.

10 May 2022

T cell behavior informs metastatic melanoma outcomes

Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn't work, and new research may help explain why.

9 May 2022

Study identifies interleukin-6 as a potential target in refining cancer therapies

Immune checkpoint inhibitors have revolutionized the treatment of many cancers by using our body's immune system to kill cancer.

9 May 2022

Targeting interleukin-6 could help reduce immune-related adverse events from immunotherapy

Researchers at The University of Texas MD Anderson Cancer Center have identified a novel strategy to reduce immune-related adverse events from immunotherapy treatment by targeting the cytokine interleukin-6 (IL-6).

9 May 2022

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

In this interview, we speak to Steffi Oesterreich, PH.D., from the University of Pittsburgh, about how new insights into a gene mutation present in 20-30% of breast cancer recurrences may have a silver lining, leading to novel treatment opportunities.

9 May 2022

Immunotherapy News and Research

Latest Immunotherapy News and Research

'Crown-like structures' surrounding breast tumors could hinder treatment response, study finds

Penn Medicine and CHOP announce plans with Costa Rica's CCSS for CAR T research

Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients

NIH team documents various types of neuropathy after COVID vaccination

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Using 'off-the-shelf' engineered stem cell based therapy for treating glioblastomas post-surgery

Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Immunotherapy combined with chemoradiation and surgery could help treat nonmetastatic gastroesophageal cancer

Immunotherapy after bladder cancer surgery helps reduce cancer recurrence

Antibiotics disrupt the immune system in the gut leading to fungal infection

Penn study finds low uptake of first mutation-targeted bladder cancer drug

Study could provide a new approach to treating metastatic triple negative breast cancer

Study modeling tumor evolution reveals a central tradeoff that could be exploited for cancer treatment

World's first Focused Ultrasound Cancer Immunotherapy Center could revolutionize cancer care

New guideline provides guidance on the use of radiation therapy to treat patients with brain metastases

T cell behavior informs metastatic melanoma outcomes

Study identifies interleukin-6 as a potential target in refining cancer therapies

Targeting interleukin-6 could help reduce immune-related adverse events from immunotherapy

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

eBook: The Ultimate Guide to Successful Immunofluorescence eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Immunotherapy News and Research

Latest Immunotherapy News and Research

eBook: The Ultimate Guide to Successful Immunofluorescence eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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