Immunotherapy News and Research

Latest Immunotherapy News and Research

Survival data for immunotherapies should be re-analyzed for potential misinterpretation, indicates study

Immune checkpoint inhibitors have transformed cancer care to the point where the popular Cox proportional-hazards model provides misleading estimates of the treatment effect, according to a new study published April 15 in JAMA Oncology.

16 Apr 2021

Study reveals new genes that program stem cells to make dendritic cells

Using a new single-cell technique, WEHI researchers have uncovered a way to understand the programming behind how stem cells make particular cell types.

16 Apr 2021

Modified immune cells may prove a game-changer for patients with late-stage cancers

Modified immune cells that ruthlessly kill cancerous tumors may prove a game-changer for people living with late-stage cancer.

15 Apr 2021

Experts to discuss advanced cancer cell and gene therapies at Summit 2021

April 29 marks a pivotal moment in cancer research when the world's brightest minds come together to discuss how to translate the success of CAR T-cell therapies for blood cancers into successful cell and gene therapies for the most complex and deadly solid tumor cancers.

15 Apr 2021

Melanoma mortality is higher in Utah than in any other state, shows report

A letter published today [April 8, 2021] by Huntsman Cancer Institute (HCI) at the University of Utah (U of U) in the New England Journal of Medicine reports that melanoma mortality among Utahns outpaced that of the rest of the United States during the period from 1975 to 2013.

12 Apr 2021

Exercise training may slow breast cancer growth by increasing anti-tumor immune response

Exercise training may slow tumor growth and improve outcomes for females with breast cancer - especially those treated with immunotherapy drugs - by stimulating naturally occurring immune mechanisms, researchers at Massachusetts General Hospital and Harvard Medical School have found.

12 Apr 2021

Yale researchers provide new insights into acquired resistance to cancer immunotherapy

New research by Yale Cancer Center shows insights into modeling resistance to immune checkpoint inhibitors, a form of cancer immunotherapy.

12 Apr 2021

CD40 drug before surgery can benefit patients with early-stage pancreatic cancer

Giving early-stage pancreatic cancer patients a CD40 immune-stimulating drug helped jumpstart a T cell attack to the notoriously stubborn tumor microenvironment before surgery and other treatments, according to a new study from researchers in the Abramson Cancer Center (ACC) at the University of Pennsylvania.

12 Apr 2021

Aneuploidy testing can be key in determining optimal treatment for lung cancer patients

Patients with non-small cell lung cancer (NSCLC) whose cancer cells have low levels of aneuploidy - an abnormal number of chromosomes - tend to respond better to immune checkpoint inhibitor drugs than patients with higher levels, Dana-Farber Cancer Institute researchers will report at the virtual AACR Annual Meeting 2021.

12 Apr 2021

Study shows how melanoma cells evade detection and destruction by immune cells

A dysfunctional immune system significantly contributes to the development of cancer. Several therapeutic strategies to activate the immune system to target cancer cells have been approved to treat different types of cancer, including melanoma.

9 Apr 2021

Increased incidence of melanoma in Utah points to overdiagnosis

A letter published today by Huntsman Cancer Institute (HCI) at the University of Utah (U of U) in the New England Journal of Medicine reports that melanoma mortality among Utahns outpaced that of the rest of the United States during the period from 1975 to 2013.

9 Apr 2021

A collaborative effort to evaluate treatment of liver and pancreatic tumors

The University of Texas MD Anderson Cancer Center and TriSalus Life Sciences today announced a strategic research collaboration to evaluate the treatment of tumors of the pancreas and liver by integrating interventional delivery of SD-101.

8 Apr 2021

NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines

A clinical trial is underway to determine whether people who are highly allergic or have a mast cell disorder are at increased risk for an immediate, systemic allergic reaction to the Moderna or Pfizer-BioNTech COVID-19 vaccines.

7 Apr 2021

New research could rescue failed immunotherapies for treating solid tumors

New research from the UVA Cancer Center could rescue once-promising immunotherapies for treating solid cancer tumors, such as ovarian, colon and triple-negative breast cancer, that ultimately failed in human clinical trials.

7 Apr 2021

Phase 1 clinical trial to test a new, potential method against cancer

A potential new weapon against cancer is entering the first phase of clinical trials thanks to a collaboration between Spectrum Health, the Lansing-based company Niowave and Michigan State University.

7 Apr 2021

High expression of cell death genes may increase risk of early death from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

5 Apr 2021

New software package employs deep-learning algorithms to analyze T-cell receptor sequencing data

Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center have developed DeepTCR, a software package that employs deep-learning algorithms to analyze T-cell receptor (TCR) sequencing data. T-cell receptors are found on the surface of immune T cells.

5 Apr 2021

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4 molecule.

3 Apr 2021

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according to a pre-clinical study for neuroblastoma and melanoma.

3 Apr 2021

Stem cell transplants offer long-term benefits for pediatric cancer patients receiving immunotherapy

Children and young adults who receive CAR T-cell therapy for the most common childhood cancer - acute lymphoblastic leukemia - suffer remarkably fewer relapses and are far more likely to survive when the treatment is paired with a subsequent stem cell transplant, a new study finds.

1 Apr 2021

Immunotherapy News and Research

Latest Immunotherapy News and Research

Survival data for immunotherapies should be re-analyzed for potential misinterpretation, indicates study

Study reveals new genes that program stem cells to make dendritic cells

Modified immune cells may prove a game-changer for patients with late-stage cancers

Experts to discuss advanced cancer cell and gene therapies at Summit 2021

Melanoma mortality is higher in Utah than in any other state, shows report

Exercise training may slow breast cancer growth by increasing anti-tumor immune response

Yale researchers provide new insights into acquired resistance to cancer immunotherapy

CD40 drug before surgery can benefit patients with early-stage pancreatic cancer

Aneuploidy testing can be key in determining optimal treatment for lung cancer patients

Study shows how melanoma cells evade detection and destruction by immune cells

Increased incidence of melanoma in Utah points to overdiagnosis

A collaborative effort to evaluate treatment of liver and pancreatic tumors

NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines

New research could rescue failed immunotherapies for treating solid tumors

Phase 1 clinical trial to test a new, potential method against cancer

High expression of cell death genes may increase risk of early death from lung cancer

New software package employs deep-learning algorithms to analyze T-cell receptor sequencing data

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

Stem cell transplants offer long-term benefits for pediatric cancer patients receiving immunotherapy

eBook: The Ultimate Guide to Successful Immunofluorescence eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Immunotherapy News and Research

Latest Immunotherapy News and Research

eBook: The Ultimate Guide to Successful Immunofluorescence eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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