Juvenile Diabetes News and Research

Latest Juvenile Diabetes News and Research

Implantable mechanotherapeutic drug delivery platform helps overcome host immune response

Implantable devices that release insulin into the body hold promise as an alternative way to treat diabetes without insulin injections or cannula insertions. However, one obstacle that has prevented their use so far is that the immune system attacks them after implantation, forming a thick layer of scar tissue that blocks insulin release.

8 Aug 2022

Researchers may be one step closer to preventing Type 1 diabetes

Australian researchers may be a step closer to preventing Type 1 diabetes after identifying a crucial protein that could prevent the autoimmune disease from taking hold.

14 Jul 2022

Blood levels of ceramides could help predict type 2 diabetes remission after gastric bypass surgery

A newly developed test could help doctors more accurately predict whether individuals who undergo gastric bypass surgery will experience a remission of type 2 diabetes within two years of the procedure, according to University of Utah Health scientists.

15 Jun 2022

Novel approach allows islet transplants to survive and control diabetes

In type 1 diabetes, an autoimmune response attacks the pancreas's insulin-producing beta cells, leading to marked fluctuations in blood sugar levels. Lifelong daily insulin treatments are standard for patients, but replacing lost beta cells through transplants of islets, a group of cells in the pancreas, represents an attractive option.

13 May 2022

Novel Type 1 diabetes treatment involves pancreatic islet transplant without the need for immunosuppression

In a new study, a team of researchers from the University of Missouri, Georgia Tech and Harvard University has demonstrated the successful use of a novel Type 1 diabetes treatment in a large animal model.

13 May 2022

Study shows how co-transplanting islet cells with SA-FasL-microgels reverses diabetic symptoms

Islet cell transplants are a promising treatment that can cure difficult-to-treat type 1 diabetes. The cells, taken from a donor pancreas, provide patients with a sustainable and tightly controlled source of insulin.

13 May 2022

Researchers design RNA molecules for delivering therapies directly to beta cells

Investigators at the University of Miami Miller School of Medicine have designed RNA molecules that home to human pancreatic beta cells, the cells that produce insulin and are destroyed in patients with type 1 and type 2 diabetes.

7 Apr 2022

Epigenetic changes could be a biomarker for early detection of type 1 diabetes

Children who develop type 1 diabetes show epigenetic changes in the cells of their immune system already before the antibodies of the disease are detected in their blood.

16 Mar 2022

Using oral blood pressure drug to treat Type 1 diabetes shows benefits for at least two years

Use of the drug verapamil to treat Type 1 diabetes continues to show benefits lasting at least two years, researchers report in the journal Nature Communications.

3 Mar 2022

Researchers identify a cellular pathway that causes pancreatic beta cells to die in type 1 diabetes

A central feature of type 1 diabetes is loss of the pancreatic beta cells that make insulin. Researchers led by Paolo Fiorina, MD, PhD, of Boston Children's Hospital and Francesca D'Addio, MD, of the University of Milan now identify a harmful cellular pathway that causes these cells to die.

3 Feb 2022

Newly discovered hormone may play a key role in the development of type 1 and type 2 diabetes

A newly discovered hormone named fabkin helps regulate metabolism and may play an important role in the development of both type 1 and type 2 diabetes, according to research led by the Sabri Ülker Center for Metabolic Research at Harvard T.H. Chan School of Public Health.

12 Dec 2021

New hormone may play a key role in the development of type 1 and type 2 diabetes

8 Dec 2021

Scientists identify new gene that contributes to type 1 diabetes progression

When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.

16 Nov 2021

Therapeutics that target ceramides may help treat cardiometabolic disease

Therapeutics that target lipids called ceramides might hold potential for treating cardiometabolic disease, argues a review article published November 5th in the journal Trends in Pharmacological Sciences.

7 Nov 2021

New convection-enhanced MEDs could offer faster, more effective treatment for T1D patients

More than 40 million people worldwide are affected with type 1 diabetes (T1D) mellitus, an autoimmune disease in which insulin producing β-cells in the pancreas are destroyed by the immune system.

6 Sep 2021

Small protein prevents immune system from destroying pancreatic cells in type 1 diabetes-prone mice

A new study has shown that treating type 1 diabetes-prone mice with the small protein MOTS-c prevented the immune system from destroying insulin-producing pancreatic cells, effectively preventing the onset of the autoimmune disease.

16 Aug 2021

Largest genetic study identifies new drug targets to treat type 1 diabetes

Scientists have completed the largest and most diverse genetic study of type 1 diabetes ever undertaken, identifying new drug targets to treat a condition that affects 1.3 million American adults.

22 Jul 2021

Novel method for glucagon delivery to help individuals living with Type 1 diabetes

For children with Type 1 diabetes, the risk of experiencing a severe hypoglycemic episode is especially common -- and for parents, the threat of that happening in the middle of the night is especially frightening.

20 Jul 2021

Scientists outline new target for treating type 2 diabetes

This year marks the 100th anniversary of the discovery of insulin, a scientific breakthrough that transformed Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, from a terminal disease into a manageable condition.

30 Jun 2021

New biomaterial for pancreatic islet transplants does not trigger the body's immune response

A multidisciplinary research team led by Jonathan Lakey, Ph.D., professor of surgery and biomedical engineering at the University of California, Irvine, has developed a biomaterial for pancreatic islet transplants that doesn't trigger the body's immune response.

4 Jun 2021

Juvenile Diabetes News and Research

Latest Juvenile Diabetes News and Research

Implantable mechanotherapeutic drug delivery platform helps overcome host immune response

Researchers may be one step closer to preventing Type 1 diabetes

Blood levels of ceramides could help predict type 2 diabetes remission after gastric bypass surgery

Novel approach allows islet transplants to survive and control diabetes

Novel Type 1 diabetes treatment involves pancreatic islet transplant without the need for immunosuppression

Study shows how co-transplanting islet cells with SA-FasL-microgels reverses diabetic symptoms

Researchers design RNA molecules for delivering therapies directly to beta cells

Epigenetic changes could be a biomarker for early detection of type 1 diabetes

Using oral blood pressure drug to treat Type 1 diabetes shows benefits for at least two years

Researchers identify a cellular pathway that causes pancreatic beta cells to die in type 1 diabetes

Newly discovered hormone may play a key role in the development of type 1 and type 2 diabetes

New hormone may play a key role in the development of type 1 and type 2 diabetes

Scientists identify new gene that contributes to type 1 diabetes progression

Therapeutics that target ceramides may help treat cardiometabolic disease

New convection-enhanced MEDs could offer faster, more effective treatment for T1D patients

Small protein prevents immune system from destroying pancreatic cells in type 1 diabetes-prone mice

Largest genetic study identifies new drug targets to treat type 1 diabetes

Novel method for glucagon delivery to help individuals living with Type 1 diabetes

Scientists outline new target for treating type 2 diabetes

New biomaterial for pancreatic islet transplants does not trigger the body's immune response

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Juvenile Diabetes News and Research

Latest Juvenile Diabetes News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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