Lung Cancer News and Research

Latest Lung Cancer News and Research

Andor's Komet software used to automatically score modified 3D 'Comet' assay results

With cancer rates rising worldwide, and Cancer Research UK predicting that the lifetime risk of cancer will reach 50% by 2027, the need for early diagnosis is overwhelming. Now, a British research group has published details of a simple empirical test to detect any early-stage cancer, relying on Andor's Komet software to automatically score the modified 3D 'Comet' assay results.

From Andor Technology Ltd. 11 Dec 2014

Carboplatin and paclitaxel show promise for advanced thymic carcinoma

A multicentre, phase II study of carboplatin and paclitaxel in chemotherapy-naïve patients with advanced thymic carcinoma has shown that the treatment has promising efficacy compared with standard anthracycline-based chemotherapy.

10 Dec 2014

Myriad Genetics highlights three new studies at SABCS 2014

Myriad Genetics, Inc. today announced results from a new study that demonstrated the ability of the myRisk Hereditary Cancer test to detect 105 percent more mutations in cancer causing genes than conventional BRCA testing alone. The Company also presented two key studies in triple negative breast cancer (TNBC) that show the myChoice HRD test accurately predicted response to platinum-based therapy in patients with early-stage TNBC and that the BRACAnalysis molecular diagnostic test significantly predicted response to platinum-based drugs in patients with metastatic TNBC.

10 Dec 2014

Heat-shock protein 90 enables ER+ breast cancers to develop resistance to hormonal therapy

Long known for its ability to help organisms successfully adapt to environmentally stressful conditions, the highly conserved molecular chaperone heat-shock protein 90 (HSP90) also enables estrogen receptor-positive (ER+) breast cancers to develop resistance to hormonal therapy.

10 Dec 2014

Cigarette smoking continues to cause nearly three in ten cancer deaths in the U.S.

A new American Cancer Society study finds that despite significant drops in smoking rates, cigarettes continue to cause about three in ten cancer deaths in the United States. The study, appearing in the Annals of Epidemiology, concludes that efforts to reduce smoking prevalence as rapidly as possible should be a top priority for the U.S. public health efforts to prevent cancer deaths.

10 Dec 2014

Advances in fight against TB, sudden cardiac death

Research projects into two of the biggest killers in worldwide health, tuberculosis and sudden cardiac death, will be the subjects of the University of Leicester Graduate School Doctoral Inaugural Lectures, delivered by two of the winners of this year's PhD prizes in the College of Medicine, Biological Sciences and Engineering.

10 Dec 2014

PD-1, PD-L1 differentially expressed in NSCLC

The expression of the immune checkpoint protein programmed death-1 receptor and its ligand varies according to tumour and patient characteristics in oncogene-addicted non-small-cell lung cancer, research indicates.

9 Dec 2014

Agent THZ1 shrinks human-like small cell lung tumors in mice

Small cell lung cancer - a disease for which no new drugs have been approved for many years - has shown itself vulnerable to an agent that disables part of tumor cells' basic survival machinery, researchers at Dana-Farber Cancer Institute and the Massachusetts Institute of Technology reported.

9 Dec 2014

Phase 2 RESONATE-17 study: IMBRUVICA (ibrutinib) improves survival in CLL patients with del 17p

Results from the Phase 2 RESONATE-17 (PCYC-1117) study show IMBRUVICA (ibrutinib) was associated with an 82.6 percent investigator-assessed overall response rate (ORR; the primary endpoint) and a 79 percent progression-free survival (PFS) rate at 12 months in people living with relapsed/refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have a genetic mutation known as deletion 17p (del 17p).

9 Dec 2014

Amgen's XGEVA (denosumab) receives FDA approval for treatment of hypercalcemia of malignancy

Amgen today announced that the U.S. Food and Drug Administration has approved a new indication for XGEVA (denosumab) for the treatment of hypercalcemia of malignancy (HCM) refractory to bisphosphonate therapy.

8 Dec 2014

Nivolumab drug highly effective for Hodgkin's lymphoma

A phase I clinical trial of nivolumab found that the immune-boosting drug is a highly effective therapy for Hodgkin's lymphoma. The multi-institution study, led by Mayo Clinic, indicated that the drug was safe and led to an 87 percent response rate in patients who had failed on other treatments.

7 Dec 2014

BeyondSpring Pharmaceuticals plans to initiate Plinabulin Phase 3 pivotal trial in NSCLC patients

BeyondSpring Pharmaceuticals, Inc., a clinical stage biopharmaceutical company focused on the development of innovative cancer therapies, today announced that it plans to initiate a Phase 3 pivotal trial of lead product candidate, Plinabulin, in patients with non-small cell lung cancer (NSCLC) in the first quarter of 2015.

4 Dec 2014

New targeted therapy shows promise in patients with ALK-positive advanced NSCLC

An international study involving Manchester researchers has found that for previously untreated lung cancer patients with a particular genetic change, a new targeted therapy is better than standard chemotherapy.

4 Dec 2014

CytRx's clinical trials for aldoxorubicin placed on partial clinical hold

CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, today announced that the Company has received written notice from the United States Food and Drug Administration that its clinical trials for aldoxorubicin have been placed on partial clinical hold.

3 Dec 2014

Exome sequencing refines 46,XY DSD diagnosis

Exome sequencing can identify a likely genetic cause of 46,XY disorders of sex development in about a third of cases, report researchers.

1 Dec 2014

Closed-loop artificial pancreas system improves diabetes management in adolescents

Research shows that the use of an artificial pancreas system helps to compensate for omission and underestimation of insulin boluses in adolescents with Type 1 diabetes.

1 Dec 2014

Congenital hypothyroidism of central origin often requires treatment

Congenital hypothyroidism of central origin should not be dismissed as a mild condition and is worth screening for, say researchers.

1 Dec 2014

Inhibin B plus baseline LH levels aids hypogonadotropic hypogonadism diagnosis in boys

Researchers recommend measuring inhibin B concentration in combination with basal luteinising hormone as a first-line test to discover the underlying cause of delayed puberty in boys.

1 Dec 2014

‘Optimal degree’ of catch-up growth defined for SGA babies

A growth trajectory in which small for gestational age babies achieve catch-up growth to a defined degree within the first few months of life appears to be best for their subsequent health, say researchers.

1 Dec 2014

Philips introduces new lung screening solution at RSNA 2014

Royal Philips today introduced a new lung screening solution designed to offer health care providers a faster and more definitive pathway to lung cancer detection and treatment. Making its debut at the 2014 Radiological Society of North America Annual Meeting in Chicago this week, this total solution is comprised of products and services that enable health care providers to implement and manage a comprehensive computed tomography (CT) lung screening program which tracks and guides patients across the health continuum.

1 Dec 2014

Lung Cancer News and Research

Latest Lung Cancer News and Research

Andor's Komet software used to automatically score modified 3D 'Comet' assay results

Carboplatin and paclitaxel show promise for advanced thymic carcinoma

Myriad Genetics highlights three new studies at SABCS 2014

Heat-shock protein 90 enables ER+ breast cancers to develop resistance to hormonal therapy

Cigarette smoking continues to cause nearly three in ten cancer deaths in the U.S.

Advances in fight against TB, sudden cardiac death

PD-1, PD-L1 differentially expressed in NSCLC

Agent THZ1 shrinks human-like small cell lung tumors in mice

Phase 2 RESONATE-17 study: IMBRUVICA (ibrutinib) improves survival in CLL patients with del 17p

Amgen's XGEVA (denosumab) receives FDA approval for treatment of hypercalcemia of malignancy

Nivolumab drug highly effective for Hodgkin's lymphoma

BeyondSpring Pharmaceuticals plans to initiate Plinabulin Phase 3 pivotal trial in NSCLC patients

New targeted therapy shows promise in patients with ALK-positive advanced NSCLC

CytRx's clinical trials for aldoxorubicin placed on partial clinical hold

Exome sequencing refines 46,XY DSD diagnosis

Closed-loop artificial pancreas system improves diabetes management in adolescents

Congenital hypothyroidism of central origin often requires treatment

Inhibin B plus baseline LH levels aids hypogonadotropic hypogonadism diagnosis in boys

‘Optimal degree’ of catch-up growth defined for SGA babies

Philips introduces new lung screening solution at RSNA 2014

The ultimate guide to lung research tools and protocols eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Lung Cancer News and Research

Latest Lung Cancer News and Research

The ultimate guide to lung research tools and protocols eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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