Lupus News and Research

Latest Lupus News and Research

Scientists at Oklahoma Medical Research Foundation identify six new Sj-gren-related genes

With the completion of the first genome-wide association study for Sj-gren's syndrome, an international coalition of researchers led by scientists at the Oklahoma Medical Research Foundation has identified six new disease-related genes.

7 Oct 2013

Researchers identify protein that triggers inflammation in patients with hemorrhage, sepsis

Investigators at The Feinstein Institute for Medical Research have discovered a protein in the human body that can trigger and mediate inflammation in patients suffering from hemorrhage and sepsis. The findings were published in the online version of Nature Medicine on October 6, 2013.

7 Oct 2013

AbbVie announces HUMIRA phase II study results for treating hidradenitis suppurativa

AbbVie (NYSE: ABBV) today announced results from a post-hoc analysis of an investigational Phase II study, which evaluated HUMIRA® (adalimumab) in the treatment of patients with moderate-to-severe hidradenitis suppurativa (HS) after 16 weeks of therapy.

7 Oct 2013

FDA approves Cimzia (certolizumab pegol) for active psoriatic arthritis

UCB announced today that the U.S. Food and Drug Administration has approved Cimzia (certolizumab pegol) for the treatment of adult patients with active psoriatic arthritis.

30 Sep 2013

c-Fos oncogene cab be important target for understanding and treatment of cancer

The c-Fos oncogene has traditionally been linked to cellular activities related to cancer, such as cell division, differentiation-conversion from one cell type to another-or survival. Any alteration of these activities can set off the development of tumours, which has made c-Fos an important target for the understanding and treatment of cancer.

29 Sep 2013

Study shows need for improved detection of sepsis for all women in labor

Rates of severe sepsis and deaths from sepsis among U.S. women hospitalized for delivery have risen sharply over the last decade, reports a study in the October issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

24 Sep 2013

Abbvie, Ablynx Ink Up To $840M RA, SLE Collaboration

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23 Sep 2013

Abbvie, Ablynx ink license agreement to develop anti-IL-6R Nanobody against inflammatory diseases

Ablynx and AbbVie today announced that they have entered into a global license agreement to develop and commercialize the anti-IL-6R Nanobody, ALX-0061, to treat inflammatory diseases.

23 Sep 2013

Antibody that binds, neutralizes HIV likely also targets the body's own self proteins

Researchers at The Scripps Research Institute discovered that an antibody that binds and neutralizes HIV likely also targets the body's own "self" proteins. This finding could complicate the development of HIV vaccines designed to elicit this protective antibody, called 4E10, and others like it, as doing so might be dangerous or inefficient.

20 Sep 2013

Parasites could be potential key to treating autoimmune diseases

There is a new weapon in the fight against autoimmune diseases such as Type 1 diabetes, rheumatoid arthritis, Crohn's disease and lupus, the common trait of which is an immune system that attacks its own organs and tissues.

10 Sep 2013

Rigel Cuts 30 Jobs, Refocuses On Three Clinical Programs

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5 Sep 2013

Rigel plans to focus on completing three clinical programs for ITP, DLE and dry eye disease

Rigel Pharmaceuticals, Inc. today announced its plans to focus the Company's resources on the completion of three lead clinical programs. These efforts include commencing a Phase 3 clinical study of fostamatinib, an oral SYK inhibitor, in Immune Thrombocytopenic Purpura pending discussions with regulatory agencies.

5 Sep 2013

Findings could alter ways in which doctors use platelets to treat traumatic injuries

A new finding could lead to novel treatments to reduce bleeding in trauma and severe infections.

2 Sep 2013

Scientists unravel how DNA damage may trigger lupus erythematosus

Summer, sun and the sea - a dream vacation for most - can turn sour for those affected by lupus erythematosus. For them, absorption of the UV-light component in sunlight may cause florid inflammation and redness of the skin. Scientists of the University Hospital Bonn, Germany have now discovered which signaling pathway of the innate immune system promotes autoimmune symptoms following sun-induced DNA damage.

30 Aug 2013

AARDA study reveals mothers antibodies may cause autism in babies

A new, large-scale study of more than 2,700 mothers of children with autism shows that about one in 10 mothers have antibodies in their bloodstream that react with proteins in the brain of their babies.

29 Aug 2013

Pulmonary hypertension may be caused by molecular pathway that damages blood vessels

Pulmonary hypertension, a deadly form of high blood pressure that develops in the lungs, may be caused by an inflammation-producing molecular pathway that damages the inner lining of blood vessels, according to a new study by researchers at the Stanford University School of Medicine.

29 Aug 2013

Study: Gene variants linked with increased risk for kidney complications in patients with lupus

Variants in a particular gene are linked with an increased risk for kidney complications in patients with lupus, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology. The findings could lead to better treatments to protect the kidney health of patients with the disease.

23 Aug 2013

NOXXON completes patient recruitment of NOX-E36 Phase IIa trial for treatment of diabetic nephropathy

NOXXON Pharma today announced the successful completion of patient recruitment of its NOX-E36 Phase IIa clinical trial for the treatment of diabetic nephropathy. NOX-E36 is a Spiegelmer® that binds and neutralizes CCL2/MCP-1 (C-C Chemokine Ligand / Monocyte Chemoattractant Protein-1), a pro-inflammatory chemokine that plays an important role in the progression of diabetic nephropathy, the most common single cause of chronic kidney failure and end-stage renal disease.

25 Jul 2013

Researchers discover mechanism that prevents immune system from spinning out of control

A team led by a University of Arizona researcher has discovered a previously unknown mechanism that prevents the immune system from going into overdrive, shedding light not only on how our body controls its response to pathogens but on conditions such as autoimmune diseases, allergies and chronic inflammation as well.

24 Jul 2013

Researchers provide new model for studying drug targets and therapies for AIH

A gene mutation disrupts the activity of certain immune cells and causes the immune system to erroneously attack the liver, according to a new animal study from the Icahn School of Medicine at Mount Sinai.

24 Jul 2013

Lupus News and Research

Latest Lupus News and Research

Scientists at Oklahoma Medical Research Foundation identify six new Sj-gren-related genes

Researchers identify protein that triggers inflammation in patients with hemorrhage, sepsis

AbbVie announces HUMIRA phase II study results for treating hidradenitis suppurativa

FDA approves Cimzia (certolizumab pegol) for active psoriatic arthritis

c-Fos oncogene cab be important target for understanding and treatment of cancer

Study shows need for improved detection of sepsis for all women in labor

Abbvie, Ablynx Ink Up To $840M RA, SLE Collaboration

Abbvie, Ablynx ink license agreement to develop anti-IL-6R Nanobody against inflammatory diseases

Antibody that binds, neutralizes HIV likely also targets the body's own self proteins

Parasites could be potential key to treating autoimmune diseases

Rigel Cuts 30 Jobs, Refocuses On Three Clinical Programs

Rigel plans to focus on completing three clinical programs for ITP, DLE and dry eye disease

Findings could alter ways in which doctors use platelets to treat traumatic injuries

Scientists unravel how DNA damage may trigger lupus erythematosus

AARDA study reveals mothers antibodies may cause autism in babies

Pulmonary hypertension may be caused by molecular pathway that damages blood vessels

Study: Gene variants linked with increased risk for kidney complications in patients with lupus

NOXXON completes patient recruitment of NOX-E36 Phase IIa trial for treatment of diabetic nephropathy

Researchers discover mechanism that prevents immune system from spinning out of control

Researchers provide new model for studying drug targets and therapies for AIH

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Lupus News and Research

Latest Lupus News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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