Metabolic Syndrome

Metabolic syndrome is a clustering of abnormalities that includes obesity, hyperglycemia, high blood pressure, and atherogenic dyslipidemia. Advances in scientific knowledge, the increasing prevalence of obesity, and the disorder's role in contributing to cardiovascular disease and diabetes are fueling interest in metabolic syndrome.

What is Metabolic Syndrome?

Metabolic syndrome is a condition characterized by the presence diabetes, obesity and high blood pressure. These conditions increase the risk of cardiovascular illnesses such as stroke and heart disease. Individually, diabetes, high blood pressure and obesity can lead to vascular damage, but a combination of these illnesses is particularly dangerous.

Metabolic Syndrome Risk Factors

Metabolic Syndrome Treatment

Metabolic Syndrome Prevention

Polycystic Ovary Syndrome and Metabolic Syndrome

Abdominal Obesity and the Metabolic Syndrome

History of Metabolic Syndrome

Metabolic Syndrome and Bariatric Surgery

Latest Metabolic Syndrome News and Research

Eating oranges daily may shift lipid patterns in fatty liver disease

A 4-week trial on 'Navelina' oranges shows potential effects on lipid metabolism in fatty liver disease, revealing intriguing but non-significant patterns.

20 Apr 2026

Ultra-processed diets may harm muscle health

Ultra-processed food diets may impair muscle health, with MRI findings showing increased fat infiltration in individuals at risk for knee osteoarthritis.

17 Apr 2026

Ultra-processed foods linked to higher obesity risk in adolescents

Adolescents who consume more ultra-processed foods (UPFs) have significantly higher odds of being overweight or obese, according to a new systematic review and meta-analysis published in the open-access journal PLOS One by Mekuriaw Nibret Aweke of the University of Gondar, Ethiopia, and colleagues.

15 Apr 2026

Metabolic syndrome doubles worldwide over two decades

A global study reveals a sharp rise in metabolic syndrome prevalence from 2000 to 2023, highlighting urgent public health challenges and regional disparities.

15 Apr 2026

Obesity health risks differ significantly between men and women

New research being presented at this year's European Congress on Obesity (ECO) in Istanbul, Turkey (12-15 May), reveals distinct patterns of heart, metabolic, and inflammatory health risks between men and women living with obesity, providing an insight into how clinicians may be able to tailor management approaches.

13 Apr 2026

Prickly pear may pack a surprising punch against metabolic syndrome

This narrative review examines how Opuntia ficus-indica fruit, or prickly pear, may help target multiple features of metabolic syndrome through its fiber, betalains, polyphenols, carotenoids, and other bioactive compounds. The authors conclude that the fruit shows promising mechanistic and preclinical potential, but stronger human trials are still needed before firm clinical claims can be made.

6 Apr 2026

American Heart Association's 9 diet rules to lower heart disease risk

The AHA's dietary guidance emphasizes food choices over fad diets to reduce heart disease risk and improve cardiovascular health across all life stages.

2 Apr 2026

Imaging study measures pancreatic fat in children and teens

Higher fat content in the pancreas of children and adolescents with obesity is associated with an increased level of heart and metabolic risk factors, including higher than average body mass index (BMI), elevated diastolic blood pressure, higher levels of abdominal and liver fat, and insulin resistance, according to new research presented at this year's European Congress on Obesity (ECO) in Istanbul, Turkey (12-15 May).

1 Apr 2026

Eating more dairy and calcium may lower metabolic syndrome odds

Research links higher dietary calcium and dairy consumption to reduced odds of metabolic syndrome, highlighting potential dietary interventions for health.

25 Mar 2026

Breast reduction surgery is linked to lower diabetes and heart risk

Findings suggest breast reduction surgery is associated with lower long-term diabetes and cardiovascular risks, enhancing women's metabolic health.

24 Mar 2026

A healthier thymus predicts longer life and lower cancer and heart disease risk in adults

Imaging-based analysis of over 27,000 adults shows that better thymic health is strongly associated with lower all-cause mortality, reduced lung cancer risk, and improved cardiovascular outcomes. The findings suggest the thymus remains biologically relevant in adulthood, linking immune aging, inflammation, and chronic disease risk, although causality cannot be established.

19 Mar 2026

Tailored prediabetes treatment may better prevent Type 2 diabetes

A one-size-fits-all approach to prediabetes treatment may miss the opportunity to implement an early, more intensive, tailored prevention approach for those with the highest risk of developing Type 2 diabetes, according to preliminary research presented at the American Heart Association's EPI|Lifestyle Scientific Sessions 2026.

17 Mar 2026

Expert consensus validates UDFF for noninvasive fatty liver assessment

As the global burden of obesity, type 2 diabetes, and metabolic syndrome continues to rise, fatty liver disease has become one of the most prevalent chronic liver conditions worldwide. Its progressive forms, including metabolic dysfunction‐associated steatohepatitis (MASH), cirrhosis, and hepatocellular carcinoma, now represent a major public health challenge.

17 Mar 2026

Skipping breakfast may raise metabolic syndrome risk

The link between skipping breakfast and metabolic syndrome highlights the need for dietary strategies to improve cardiometabolic health in at-risk populations.

16 Mar 2026

Updated guideline emphasizes earlier treatment for high cholesterol

The American College of Cardiology (ACC), the American Heart Association and nine other leading medical associations, today issued an updated guideline for the management of dyslipidemia-abnormal levels of one or more types of lipids or lipoproteins in the blood, including cholesterol and triglycerides.

13 Mar 2026

New digital shield against metabolic disease in youth psychosis

A new clinic-ready web-based risk prediction tool called PsyMetRiC is now available to forecast the risk of young people with psychosis developing cardiometabolic disorders such as obesity, metabolic syndrome and diabetes.

12 Mar 2026

Weekend lie-ins may boost insulin sensitivity, but too much may backfire

This study explores the relationship between sleep patterns and insulin sensitivity, emphasizing the impact of weekday sleep and weekend catch-up on metabolism.

6 Mar 2026

Puberty reshapes DNA to worsen or reverse insulin resistance

This study uncovers epigenetic changes during puberty that correlate with insulin resistance, offering insights into childhood obesity and metabolic risk.

3 Mar 2026

New review explains how circular RNAs could unlock fat browning therapies

A Cell Death & Disease review synthesizes preclinical evidence that circular RNAs regulate adipose browning and metabolic pathways through microRNA interactions, protein binding, and organelle-linked stress mechanisms. It highlights their biomarker and therapeutic potential in obesity and type 2 diabetes while underscoring key translational challenges, including delivery specificity and human validation.

26 Feb 2026

Heavy alcohol intake is associated with dangerous belly fat accumulation, large UK study shows

In a large UK population cohort, higher weekly alcohol consumption was dose-dependently associated with greater visceral fat mass measured by DXA, independent of total body fat. Heavy drinkers showed over 10% higher proportional visceral fat compared with lower consumption groups, a pattern linked to increased cardiometabolic risk.

26 Feb 2026