Metabolic Syndrome

Metabolic syndrome is a clustering of abnormalities that includes obesity, hyperglycemia, high blood pressure, and atherogenic dyslipidemia. Advances in scientific knowledge, the increasing prevalence of obesity, and the disorder's role in contributing to cardiovascular disease and diabetes are fueling interest in metabolic syndrome.

What is Metabolic Syndrome?

Metabolic syndrome is a condition characterized by the presence diabetes, obesity and high blood pressure. These conditions increase the risk of cardiovascular illnesses such as stroke and heart disease. Individually, diabetes, high blood pressure and obesity can lead to vascular damage, but a combination of these illnesses is particularly dangerous.

History of Metabolic Syndrome

Metabolic Syndrome Risk Factors

Metabolic Syndrome Prevention

Metabolic Syndrome Treatment

Metabolic Syndrome and Bariatric Surgery

Polycystic Ovary Syndrome and Metabolic Syndrome

Abdominal Obesity and the Metabolic Syndrome

Latest Metabolic Syndrome News and Research

Metabolic syndrome in midlife linked to higher dementia risk

Having a larger waistline, high blood pressure and other risk factors that make up metabolic syndrome is associated with an increased risk of young-onset dementia, according to a study published on April 23, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

23 Apr 2025

Interferon regulatory factor 8 identified as key driver of liver fat buildup in NAFLD

Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance. Interferon regulatory factor 8 (IRF8) is well known for its roles in immune cell differentiation and tumor pathogenesis; however, its role in regulating glucose homeostasis and lipid metabolism remains unclear.

22 Apr 2025

New $15 million study aims to understand cardiovascular and kidney disease risk factors in women

Research teams from Augusta University, Massachusetts General Hospital and The Ohio State University will lead a $15 million project dedicated to studying the various ways that risk factors for cardiovascular and kidney diseases impact women.

22 Apr 2025

Metabolic syndrome found to increase risk of breast cancer recurrence and death

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) and published in The Journal of Internal Medicine shows that, in survivors of breast cancer, having an unhealthy metabolic profile or so called 'metabolic syndrome' increases the risk of breast cancer recurrence by 69%, and subsequent breast cancer mortality by 83%.

16 Apr 2025

Weight-loss lifestyle changes slow bone loss in older adults

Researchers evaluate the effects of a weight-loss lifestyle intervention on age-related bone deterioration.

14 Apr 2025

Two plant-based diets linked to similar survival benefits and low environmental impact

Two plant-based diets were associated with similar survival benefits and low environmental impact, according to research presented today at ESC Preventive Cardiology 2025, a scientific congress of the European Society of Cardiology (ESC).

4 Apr 2025

Smoothies with seeds may improve glycemic control, study shows

Blending whole fruits into smoothies may reduce glycemic spikes compared to eating fruit whole or drinking juice, especially when seeds are included. Researchers urge a re-evaluation of public health guidelines that currently limit smoothie intake.

3 Apr 2025

American College of Physicians announces $260,000 in grants to advance equitable obesity care

Today, the American College of Physicians (ACP) announced that it has awarded a total of $260,000 in grants to support regional programs that address equity challenges in obesity care.

3 Apr 2025

Exploring the relationship between testosterone and men's health

The review article titled"Testosterone and men's health: An in-depth exploration of their relationship", was published on February 18, 2025 in UroPrecision.

2 Apr 2025

Scientists link emulsifiers in processed foods to allergy and immune disorders

Review identifies common food additives in ultra-processed foods—particularly emulsifiers like carrageenan and polysorbate 80—as key drivers of gut dysbiosis, inflammation, and allergic diseases by disrupting intestinal barriers and activating proinflammatory pathways.

26 Mar 2025

A pecan a day keeps bad cholesterol away

Daily consumption of 57g of pecans for 12 weeks improved cholesterol profiles and diet quality in adults at risk of cardiometabolic disease, without affecting vascular health. Replacing typical snacks with pecans led to higher intake of healthy fats and fiber, and reduced carbohydrate consumption.

24 Mar 2025

Skipping exercise? Just sitting less may still improve your metabolic health

Older adults who limit their sedentary time have lower metabolic syndrome risk, regardless of how active they are or how healthy they eat. Even light movement can support better metabolic health when replacing prolonged sitting.

24 Mar 2025

Mediterranean diet shows promise in easing psoriasis, acne, and hidradenitis suppurativa

A recent review highlights how the Mediterranean diet can reduce inflammation and improve outcomes for chronic skin conditions like psoriasis, acne, and hidradenitis suppurativa by modulating key inflammatory pathways and supporting metabolic health.

19 Mar 2025

Better heart health slows brain aging and lowers dementia risk, study finds

A JAMA Network Open study finds that better cardiovascular health (CVH) in older adults is linked to lower levels of neurodegenerative biomarkers, particularly neurofilament light chain (NfL). These benefits are consistent across races and especially impactful for individuals carrying Alzheimer's-related genetic risks.

16 Mar 2025

Breast cancer deaths expected to fall in the EU and UK by 2025 across most age groups

Death rates from breast cancer will fall in 2025 in every age group in the EU and the UK apart from in EU patients aged 80 years and older. In these older patients, overall mortality rates from the disease are predicted to rise by nearly 10% in 2025.

12 Mar 2025

Tirzepatide helps people without diabetes lose 13% body weight in real-world study

A real-world study of over 4,000 US patients without type 2 diabetes found that those who persisted with Tirzepatide for at least six months lost an average of 12.9% of their body weight. The study highlights Tirzepatide’s potential as an effective off-label obesity treatment before its formal FDA approval for weight loss.

11 Mar 2025

Daily mango consumption may improve insulin sensitivity in overweight or obese adults

New research has uncovered a potential gamechanger for improving cardiometabolic health: fresh mangos.

5 Mar 2025

How much plastic are you eating? This new tool finds out

Researchers developed the 24-hour dietary recall–plastic exposure (24DR-PE) tool to assess and quantify dietary plastic exposure, aiming to link it with real-world health impacts.

4 Mar 2025

Surprising study reveals dads’ weight and diet don’t impact baby’s size

A study shows paternal health factors like BMI and diet do not influence birth weight or length, emphasizing maternal diet's critical role in pregnancy.

4 Mar 2025

MEDI method unlocks new way to decode dietary habits

"Tell me what you eat and I will tell you who you are"—this well-known saying accurately describes the new MEDI method for decoding dietary habits from DNA fragments that was developed at Med Uni Graz in cooperation with an international research team.

2 Mar 2025