Metabolism News and Research

Latest Metabolism News and Research

Vascular dysfunction may be the cause of metabolic changes that can lead to diabetes, study suggests

A major risk factor for diabetes, insulin resistance occurs when the cells of the body do not respond to insulin and cannot make use of the glucose (sugar) in the blood stream.

5 Aug 2022

KAIST researchers engineer a bacterial strain capable of producing lutein

A research group at KAIST has engineered a bacterial strain capable of producing lutein. The research team applied systems metabolic engineering strategies, including substrate channeling and electron channeling, to enhance the production of lutein in an engineered Escherichia coli strain.

4 Aug 2022

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

In a potential game changer for patients with type 2 diabetes, a team of researchers at the Diabetes, Obesity, and Metabolism Institute (DOMI) at the Icahn School of Medicine at Mount Sinai has identified a therapeutic target for the preservation and regeneration of beta cells (β cells)-;cells in the pancreas that produce and distribute insulin.

4 Aug 2022

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience.

4 Aug 2022

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

We are increasingly being exposed to endocrine-disrupting chemicals (EDCs) that interfere with the normal functioning of our hormones. Bisphenol A (BPA) and phthalates, which are widely used in consumer products including plastics, aluminum cans, pharmaceuticals, and cosmetics, are well-known EDCs.

4 Aug 2022

Fully reduced form of vitamin K found to efficiently inhibit ferroptotic cell death

A team of researchers at Tohoku University has reported on a novel function of vitamin K, which is generally known for its importance in blood clotting.

4 Aug 2022

Cold exposure could make it harder for cancer cells to grow, mice study shows

Turning down the thermostat seems to make it harder for cancer cells to grow, according to a study in mice by researchers at Karolinska Institutet in Sweden.

3 Aug 2022

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

In this interview, we speak to Tom Kostrzewski, VP of Science and Technology at CN Bio, about their organ-on-a-chip product and the future of drug discovery.

From CN-Bio 3 Aug 2022

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

Liver cancer's rapid growth leads to a vulnerability in its energy-production and cell-building processes that may be potently exploited with a new combination-treatment strategy, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

3 Aug 2022

New research unravels why breastmilk-fed preemies are healthier than formula-fed infants

Human breastmilk has long been considered "liquid gold" among clinicians treating premature infants in a newborn intensive care unit.

2 Aug 2022

Study highlights the urgent need to evaluate deficiencies in the energy balance model for the prevention and treatment of obesity

In a new study, researchers highlighted the urgent need to substitute highly processed carbohydrates with minimally processed carbohydrates or healthy fats to cease the obesity pandemic that continues relentlessly.

2 Aug 2022

Epigenetic changes prevent iron-associated programmed cell death in leukemia, research shows

The article, published in the journal Redox Biology by the group of Dr. Manel Esteller, shows that epigenetic changes prevent iron-associated programmed cell death in leukemia and show a new target for treatment with experimental drugs.

1 Aug 2022

Improving dialogue between healthcare professionals and patients in bladder cancer

In this interview, Dr. Ignacio Duran and Alex Filicevas focus on improving dialogue between healthcare professionals and patients, outlining ways in which we can encourage open discussion to improve the overall patient experience.

From Janssen Pharmaceuticals 1 Aug 2022

Nutritive intervention could be an effective treatment method in maintaining human health

In a new study, researchers assessed the impact of dietary regulation on human health and disease.

1 Aug 2022

Higher insulin dose is positively linked with cancer incidence, study finds

Dr. Yuanjie Mao has led a study published in the Journal of the American Medical Association (JAMA) Oncology looking at the correlation between daily insulin dose and cancer incidence (the number of new cases) among patients with type 1 diabetes, finding that higher insulin dose is positively associated with cancer incidence and that the association is stronger among those with insulin resistance.

29 Jul 2022

Prenatal opioid exposure may cause long-term neurological or behavioral effects later in a child's life

While infants exposed to opioids during their mother's pregnancy have been linked to adverse health outcomes, a new study at the University of Missouri has found prenatal opioid exposure could trigger long-term neurological or behavioral effects later in a child's life.

29 Jul 2022

Study highlights impaired ketogenesis as a potential confounder of severe COVID-19

In severe Covid-19 patients, the metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order to fight the virus effectively.

28 Jul 2022

Metabolism News and Research

Latest Metabolism News and Research

Vascular dysfunction may be the cause of metabolic changes that can lead to diabetes, study suggests

KAIST researchers engineer a bacterial strain capable of producing lutein

Discovery could prevent insulin resistance and have significant benefits for people with type 2 diabetes

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

Fully reduced form of vitamin K found to efficiently inhibit ferroptotic cell death

Cold exposure could make it harder for cancer cells to grow, mice study shows

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

New research unravels why breastmilk-fed preemies are healthier than formula-fed infants

Study highlights the urgent need to evaluate deficiencies in the energy balance model for the prevention and treatment of obesity

Epigenetic changes prevent iron-associated programmed cell death in leukemia, research shows

Improving dialogue between healthcare professionals and patients in bladder cancer

Nutritive intervention could be an effective treatment method in maintaining human health

Higher insulin dose is positively linked with cancer incidence, study finds

Prenatal opioid exposure may cause long-term neurological or behavioral effects later in a child's life

Study highlights impaired ketogenesis as a potential confounder of severe COVID-19

People with unhealthy sleep behaviors could develop fatty liver disease

Everything you need to know about Paxlovid — especially, should you take it?

Researchers unravel how one gut bacterium influences immunity

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production