Metabolism News and Research

Latest Metabolism News and Research

Study points to a new direction for the development of NAMPT-targeted cancer therapies

In this new article publication from Acta Pharmaceutica Sinica B, authors Ying Wu, Congying Pu, Yixian Fu, Guoqiang Dong, Min Huang and Chunquan Sheng from Second Military Medical University, Shanghai, China and University of Chinese Academy of Sciences, Shanghai, China discuss how NAMPT-targeting PROTAC promotes antitumor immunity via suppressing myeloid-derived suppressor cell expansion.

18 Jun 2022

Drug combinations may help to slow the progression of diabetic kidney disease

A mouse study led by Washington University School of Medicine in St. Louis suggests that combining SGLT2 inhibitors — a newer class of diabetes medications that lowers blood sugar — with older diabetes drugs may help to slow the progression of diabetic kidney disease.

15 Jun 2022

Blood levels of ceramides could help predict type 2 diabetes remission after gastric bypass surgery

A newly developed test could help doctors more accurately predict whether individuals who undergo gastric bypass surgery will experience a remission of type 2 diabetes within two years of the procedure, according to University of Utah Health scientists.

15 Jun 2022

Diet supplemented with or deficient in methionine affects gene expression related to liver cell fat metabolism

Having shown that diet can influence gene expression, science is starting to find out more about how this happens.

15 Jun 2022

Study reveals how acculturation affects the dietary patterns of non-U.S.-born adolescents

A new study has revealed how acculturation -; the process of assimilating to a different culture -; can affect the dietary patterns of adolescents who move to the U.S.

14 Jun 2022

Study shows how consumption of ultraprocessed foods affects children

A new study found that children ages 3 to 5 who consumed more ultraprocessed foods had poorer locomotor skills than children who consumed less of these foods. It also showed lower cardiovascular fitness in 12- to 15-year-olds who consumed more ultraprocessed foods.

14 Jun 2022

New studies examine the causes and effects of COVID-19-related food insecurity

The COVID-19 pandemic affected people at all stages of life from seniors to newborns. New studies presented at NUTRITION 2022 LIVE ONLINE examine the causes and effects of COVID-19-related food insecurity, how the pandemic affected breastfeeding practices and more.

14 Jun 2022

Lifestyle factors play a beneficial role in the prevention of Alzheimer's and related dementias

As rates of Alzheimer's disease and other forms of dementia continue to rise in the U.S., new evidence suggests that lifestyle factors such as diet, exercise and sleep play an important role in reducing the risk of developing dementia.

14 Jun 2022

Understanding how diet and the microbiome impact colorectal cancer rates

While recommended screenings beginning at age 45 have helped decrease colorectal cancer cases in older adults, cancer rates are continuing to increase in younger populations.

14 Jun 2022

Taste-related genes may play a role in determining food choices, finds study

Preliminary findings from a new study involving more than 6,000 adults found that taste-related genes may play a role in determining food choices and could, in turn, influence cardiometabolic health.

14 Jun 2022

Center-based childcare may improve health and developmental outcomes in children

A new study conducted in Canada found that children who attended center-based childcare between 1 and 4 years of age had a lower body mass index (BMI) and were less likely to be overweight or obese in later childhood than children who had non-parental childcare that was home-based or provided by relatives or nannies.

14 Jun 2022

New potato processing technique slows starch digestion to avoid blood sugar spikes

Researchers announced early tests of a new potato processing technique designed to make our bodies digest potato starch more slowly.

14 Jun 2022

Most U.S. adults lack an accurate understanding of the healthfulness of their diet

How healthy is your diet? It seems like a simple question, but according to a new study, it's one that most Americans struggle to get right.

14 Jun 2022

Five new studies shed light on the eating behaviors and diets of teens, young adults

The developmental changes and growing independence that characterize adolescence and young adulthood can make these stages of life both exciting and challenging.

14 Jun 2022

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

Researchers from the Department of Pathology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) have identified a new metabolic mechanism in liver cancer cells, by which macropinocytosis, an endocytic process, is used to engulf extracellular proteins as fuels to support the unlimited growth of hepatocellular carcinoma (HCC) in hypoxia (oxygen deprivation).

14 Jun 2022

Researchers demonstrate the feasibility of pancreatic beta-cell, target-specific CAR-Treg treatment for T1D

Researchers have successfully treated type 1 diabetes in mice using pancreatic beta-cell, target-specific, chimeric antigen-receptor (CAR) regulatory T cells (Tregs), and demonstrated the feasibility of their approach to treat the human condition according to data being presented Monday, June 13 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

'Forever chemicals' associated with greater risk of high blood pressure in middle-aged women

Middle-aged women with higher blood concentrations of common synthetic chemicals called per- and polyfluoroalkyl substances (PFAS), also called "forever chemicals" and found in water, soil, air and food, were at greater risk of developing high blood pressure, compared to their peers who had lower levels of these substances, according to new research published today in Hypertension, an American Heart Association journal.

13 Jun 2022

Scientists find new link between high-fat, high-fructose diets and Type 2 diabetes mellitus

Those who are habitually inclined to consume burgers, fries and soda may think twice about their dietary choices following scientists' latest findings about high-fat, high-fructose diets.

10 Jun 2022

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.

10 Jun 2022

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

A drug used to target IDH1 mutations in select cancers also appears to inhibit the wild-type form of the enzyme, under certain conditions.

9 Jun 2022

Metabolism News and Research

Latest Metabolism News and Research

Study points to a new direction for the development of NAMPT-targeted cancer therapies

Drug combinations may help to slow the progression of diabetic kidney disease

Blood levels of ceramides could help predict type 2 diabetes remission after gastric bypass surgery

Diet supplemented with or deficient in methionine affects gene expression related to liver cell fat metabolism

Study reveals how acculturation affects the dietary patterns of non-U.S.-born adolescents

Study shows how consumption of ultraprocessed foods affects children

New studies examine the causes and effects of COVID-19-related food insecurity

Lifestyle factors play a beneficial role in the prevention of Alzheimer's and related dementias

Understanding how diet and the microbiome impact colorectal cancer rates

Taste-related genes may play a role in determining food choices, finds study

Center-based childcare may improve health and developmental outcomes in children

New potato processing technique slows starch digestion to avoid blood sugar spikes

Most U.S. adults lack an accurate understanding of the healthfulness of their diet

Five new studies shed light on the eating behaviors and diets of teens, young adults

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

Researchers demonstrate the feasibility of pancreatic beta-cell, target-specific CAR-Treg treatment for T1D

'Forever chemicals' associated with greater risk of high blood pressure in middle-aged women

Scientists find new link between high-fat, high-fructose diets and Type 2 diabetes mellitus

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production