Metabolism News and Research

Latest Metabolism News and Research

First-in-class, anti-cancer mitochondrial drug found to be effective against most carcinoma cell lines

A study of the lead agent (CPI-613) in a class of anticancer drugs undergoing Food and Drug Administration (FDA) approved clinical trials reveals that CPI-613 is effective against most carcinoma cell lines, and, used in combination, could have efficacy against reducing some tumors.

9 Jun 2022

Targeting fatty acid metabolism holds promise for Parkinson's disease

The human brain is lipid rich. Lipids and fatty acids contribute to many important cellular processes. Alpha-synuclein -; a protein that plays a critical role in Parkinson's disease (PD) -; is known to interact with and alter the balance of lipids and fatty acids.

9 Jun 2022

Research explores effects of iron status on risk of sepsis and severe COVID-19

In a recent article posted to the medRxiv* preprint server, investigators demonstrated a link between high iron status and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)- and sepsis-linked hospitalizations.

7 Jun 2022

Ketogenic diet promotes muscle stem cell resilience but slows injury repair in mice

Fasting sends muscle stem cells into a deep resting state that slows muscle repair but also makes them more resistant to stress, according to a Stanford Medicine study of laboratory mice.

7 Jun 2022

Experts weigh evidence for and against incorporating ultra-processed foods into dietary guidelines

Dietary guidelines form the basis for nutrition advice and regulations around the world. While there is strong scientific consensus around most existing guidelines, one question has recently stirred debate: Should consumers be warned to avoid ultra-processed foods?

7 Jun 2022

Discovery may lead to new treatments to reduce inflammation in vitiligo disease

A new study, led by researchers from the University of California, Irvine, reveals the unique cell-to-cell communication networks that can perpetuate inflammation and prevent repigmentation in patients with vitiligo disease.

7 Jun 2022

Profound neuroinflammation associated with long COVID

Around 36 to 53% of coronavirus disease 2019 (COVID-19) patients develop persistent chronic symptoms, often referred to as long COVID or PASC.

7 Jun 2022

Etiologies of liver cancer are changing and the prognosis is mixed, study says

The primary causes of liver cancer are well known: viral (hepatitis B and C), alcohol and non-alcoholic steatohepatitis (NASH), a condition in which fat builds up in the liver, resulting in chronic inflammation and damage.

7 Jun 2022

Substances touted to improve athletic performance and high fat diet fuel pancreatic cancer’s development

Researchers at the University of Michigan Rogel Cancer Center have found a cell nuclear receptor activated by high fat diets and synthetic substances in unregulated athletic performance enhancers fuels the progression of precancerous pancreas lesions into pancreatic cancer.

1 Jun 2022

UCI-led study identifies sex-specific circuits of muscle signaling to other tissues

A new University of California, Irvine-led study identifies sex-specific circuits of muscle signaling to other tissues and that the organs and processes muscle impacts are markedly different between males and females.

31 May 2022

Liver4Life research team treated damaged liver in a machine and then implanted the recovered organ

The multidisciplinary Zurich research team Liver4Life has succeeded in doing something during a treatment attempt that had never been achieved in the history of medicine until now: it treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.

31 May 2022

A multi-pronged effort needed to ensure all patients with obesity get better care

When a person with diabetes, high blood pressure, or osteoarthritis goes to their primary care clinic, they expect treatment that's grounded in modern medical evidence.

31 May 2022

Scientists develop new way to attack synovial sarcoma using an investigational drug

Researchers at Washington University School of Medicine in St. Louis have developed a way to attack synovial sarcoma -; a rare tumor of soft tissues, such as ligaments and muscles -; using an investigational drug that triggers cell death.

31 May 2022

Researchers reveal a possible biological mechanism connecting breast cancer and type 2 diabetes

Breast cancer and type 2 diabetes would seem to be distinctly different diseases, with commonality only in their commonality.

30 May 2022

Researchers discover bifunctional lipopeptide antibiotic with a low resistance potential

Through bioinformatic prospecting, researchers discovered and synthesized a novel, naturally inspired bifunctional lipopeptide antibiotic with a low resistance potential.

27 May 2022

Common type 2 diabetes medication could be the key to improving fertility in women with obesity

Researchers may have found a solution to improving fertility in women with obesity, following a successful trial in mice using diabetes medication to reduce blood glucose levels.

26 May 2022

New initiative aims to increase collaboration and accelerate high-impact cancer immunotherapy

The accelerated advancement of cancer immunology and immunotherapy, a type of biological therapy that boosts the immune system's ability to recognize and kill cancer cells, has significantly improved the effectiveness of cancer treatment and patient outcomes.

25 May 2022

Robust biomarker panel could help predict gestational diabetes in early pregnancy

UCLA researchers have taken the initial step in identifying what may be an effective way to detect gestational diabetes mellitus (GDM) earlier in pregnancy, potentially improving diagnosis and treatment for what is the most common disorder of pregnancy.

25 May 2022

Lowering blood glucose levels could improve fertility in females with obesity

Reproductive hormone levels in females with obesity may be partially restored by lowering blood glucose levels, leading to improved fertility, according to a study published in the Journal of Endocrinology.

25 May 2022

Vaccinated people with breakthrough SARS-CoV-2 infection can experience debilitating long COVID

Even vaccinated people with mild breakthrough COVID-19 infections can experience debilitating, lingering symptoms that affect the heart, brain, lungs and other parts of the body, according to new research from Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System.

25 May 2022

Metabolism News and Research

Latest Metabolism News and Research

First-in-class, anti-cancer mitochondrial drug found to be effective against most carcinoma cell lines

Targeting fatty acid metabolism holds promise for Parkinson's disease

Research explores effects of iron status on risk of sepsis and severe COVID-19

Ketogenic diet promotes muscle stem cell resilience but slows injury repair in mice

Experts weigh evidence for and against incorporating ultra-processed foods into dietary guidelines

Discovery may lead to new treatments to reduce inflammation in vitiligo disease

Profound neuroinflammation associated with long COVID

Etiologies of liver cancer are changing and the prognosis is mixed, study says

Substances touted to improve athletic performance and high fat diet fuel pancreatic cancer’s development

UCI-led study identifies sex-specific circuits of muscle signaling to other tissues

Liver4Life research team treated damaged liver in a machine and then implanted the recovered organ

A multi-pronged effort needed to ensure all patients with obesity get better care

Scientists develop new way to attack synovial sarcoma using an investigational drug

Researchers reveal a possible biological mechanism connecting breast cancer and type 2 diabetes

Researchers discover bifunctional lipopeptide antibiotic with a low resistance potential

Common type 2 diabetes medication could be the key to improving fertility in women with obesity

New initiative aims to increase collaboration and accelerate high-impact cancer immunotherapy

Robust biomarker panel could help predict gestational diabetes in early pregnancy

Lowering blood glucose levels could improve fertility in females with obesity

Vaccinated people with breakthrough SARS-CoV-2 infection can experience debilitating long COVID

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production