Metabolism News and Research

Latest Metabolism News and Research

Researchers receive NIH grants to develop new treatments for neglected tropical diseases

Researchers at Washington University School of Medicine in St. Louis have received two grants from the National Institutes of Health totaling more than $5.5 million to develop new treatments for two types of devastating parasitic infections common in sub-Saharan Africa and Central and South America: river blindness and intestinal worm infections.

22 Dec 2021

Study points toward an alternative drug strategy to stall Alzheimer’s neurodegeneration

Boosting levels of the neurotransmitter norepinephrine with atomoxetine, a repurposed ADHD medication, may be able to stall neurodegeneration in people with early signs of Alzheimer's disease, a study conducted at Emory Brain Health Center suggests.

22 Dec 2021

Newly discovered species of Enterococcus bacteria named after the John Innes Centre

A newly discovered species of antibiotic-resistant bacteria has been named after the academic institute where it was identified – the John Innes Centre.

22 Dec 2021

Amino acid valine plays a key role in the growth of T cell acute lymphoblastic leukemia

A molecular building block of many animal proteins, the amino acid valine, plays a key role in cancerous growth seen in T cell acute lymphoblastic leukemia, a new study shows.

22 Dec 2021

High-altitude activities may increase the risk of hypoglycemia in people with diabetes

People with diabetes may need to monitor their blood sugar more closely when doing high-altitude activities such as hiking or skiing, according to a small study published in the Society's Journal of Clinical Endocrinology & Metabolism.

22 Dec 2021

Promising new drug target for TB identified

Mycobacterium tuberculosis (Mtb), the hardy bacterial species that causes tuberculosis (TB), has an unexpected vulnerability that future drugs may be able to exploit, according to a study from researchers at Weill Cornell Medicine.

21 Dec 2021

SGLT2 inhibitor empagliflozin can be used to treat insulin resistance in the brain, finds study

Overweight or obesity, an unfavorable distribution of fat in the body and the development of type 2 diabetes are often associated with a reduced effect of the hormone insulin in many organs, including the brain (insulin resistance).

21 Dec 2021

Researchers use machine learning to shed light on genetic mutations linked with spina bifida

Weill Cornell Medicine researchers are using machine learning, a form of artificial intelligence, to shed light on genetic mutations associated with spina bifida.

20 Dec 2021

New study shows how regular exercise protects against fatty liver disease

Exercise not only trains the muscles but can also prevent the development of fatty liver. A new study by the German Center for Diabetes Research, Helmholtz Munich and Tübingen University Hospital shows which molecular adaptations, in particular of the liver mitochondria, can be observed in this process.

20 Dec 2021

UBR7 protein acts as a histone chaperone during DNA replication, study finds

The protein UBR7 acts as a histone chaperone, regulating histone re-deposition at specific sites during DNA replication, according a recent study published in The EMBO Journal.

20 Dec 2021

Study reveals chromosome-level changes that relate to drug resistance in melanoma

Precision therapies targeting melanoma and other cancers have improved patient survival, but tumors often stop responding to drugs, and recent studies point to changes in DNA – both inside and outside chromosomes – as a driving factor in tumor genesis as well as in treatment resistance.

20 Dec 2021

Impact of acute kidney injury associated gene expression in human kidney cells

A new study attempts to perform a comparative single-cell census of human kidneys employing samples from individuals suffering from acute kidney injury and controls without the condition.

20 Dec 2021

Traditional medicinal plant alleviates malaria symptoms in mice

The active plant ingredient anemonin could provide a new approach in the treatment of malaria. It was identified by researchers from Ethiopia and Germany in a buttercup that is traditionally used in some African countries as a medicinal plant to treat malaria.

20 Dec 2021

Succinate receptor can be a potential target for cancer treatment

Cancer cells show unchecked rapid growth beyond tissue boundaries that is no longer stopped by normal control mechanisms. Due to this rapid growth, the metabolism of cancer cells is altered compared to that of cells that grow normally.

18 Dec 2021

Specific diets have less effect on IBS symptoms than expected

Many IBS sufferers avoid certain types of food and often exclude gluten. However, a large new study from Chalmers University of Technology and Uppsala University, Sweden, does not show a relationship between high intake of gluten and increased IBS symptoms.

16 Dec 2021

Gap in the use of insulin pumps, CGMs among Black and white Medicare beneficiaries widened

The gap in the use of insulin pumps and continuous glucose monitors (CGMs) among Black and white Medicare beneficiaries widened from 2017-2019, according to new research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

16 Dec 2021

Novel imaging method used to map glycosylation patterns linked with Alzheimer’s disease

Using new methodology, University of Kentucky researchers have mapped the variations in sugar chains attached to brain proteins from deceased healthy individuals or individuals with Alzheimer's disease.

15 Dec 2021

New stroke treatment imitates the survival strategy of C. elegans

Each year, some 200,000 people in Germany and 1 million people in Europe suffer a stroke. This happens when blood clots obstruct major vessels and there is no longer sufficient supply of blood to the brain.

14 Dec 2021

11 exceptional recipients of the 2021 Lupus Innovation Award announced

The Lupus Research Alliance proudly announced today 11 research grant recipients in the U.S. and around the world of the 2021 Lupus Innovation Award which will fund wide ranging areas from probing the development and progression of lupus to pointing to potential personalized therapies.

14 Dec 2021

New guidelines for heart-healthy eating

We speak to Dr. Alice Lichtenstein about the American Heart Association’s latest guidelines for a heart-healthy diet, and how they can be applied across different lifestyles.

14 Dec 2021

Metabolism News and Research

Latest Metabolism News and Research

Researchers receive NIH grants to develop new treatments for neglected tropical diseases

Study points toward an alternative drug strategy to stall Alzheimer’s neurodegeneration

Newly discovered species of Enterococcus bacteria named after the John Innes Centre

Amino acid valine plays a key role in the growth of T cell acute lymphoblastic leukemia

High-altitude activities may increase the risk of hypoglycemia in people with diabetes

Promising new drug target for TB identified

SGLT2 inhibitor empagliflozin can be used to treat insulin resistance in the brain, finds study

Researchers use machine learning to shed light on genetic mutations linked with spina bifida

New study shows how regular exercise protects against fatty liver disease

UBR7 protein acts as a histone chaperone during DNA replication, study finds

Study reveals chromosome-level changes that relate to drug resistance in melanoma

Impact of acute kidney injury associated gene expression in human kidney cells

Traditional medicinal plant alleviates malaria symptoms in mice

Succinate receptor can be a potential target for cancer treatment

Specific diets have less effect on IBS symptoms than expected

Gap in the use of insulin pumps, CGMs among Black and white Medicare beneficiaries widened

Novel imaging method used to map glycosylation patterns linked with Alzheimer’s disease

New stroke treatment imitates the survival strategy of C. elegans

11 exceptional recipients of the 2021 Lupus Innovation Award announced

New guidelines for heart-healthy eating

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production