Metabolism News and Research

Latest Metabolism News and Research

Neural network 'hallucinates' proteins with new, stable structures

Just as convincing images of cats can be created using artificial intelligence, new proteins can now be made using similar tools. In a report in Nature, a team including researchers at the University of Washington, Rensselaer Polytechnic Institute, and Harvard University describe the development of a neural network that "hallucinates" proteins with new, stable structures.

1 Dec 2021

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS.

From CN-Bio 1 Dec 2021

Novel anti-inflammatory drug target identified by CRISPR

In this interview, News-Medical speaks to Dr. Jeffrey Rathmell about his recent research into how metabolic pathways impact immune function.

1 Dec 2021

Scientists discover low amounts of cholesterol in tumor-associated macrophages

Significant changes in lipid metabolism are known to occur in cells associated with non-small-cell lung carcinoma – the most common form of lung cancer.

30 Nov 2021

Study uncovers new mechanism to explain how obesity jeopardizes the functions of skeletal muscle

A decline in metabolism and endurance of skeletal muscle is commonly observed in obese patients, but the underlying mechanism is not well-understood.

30 Nov 2021

Experimental compound reduces diabetic complications in mice

An experimental compound reduced complications of type 1 and type 2 diabetes in mice—not by lowering blood sugar—but by countering its consequences of cell death, inflammation, and organ damage.

24 Nov 2021

Exosomes involved in the progression of breast cancer in patients with obesity, diabetes

Obesity, insulin resistance and Type 2 diabetes are risk factors for breast cancer in post-menopausal women. The metabolic and inflammatory complications of obesity have a role in the formation of cancer.

24 Nov 2021

Study reveals distinct gut microbial 'signatures' highly responsive to dietary therapy for IBS

People who respond well to the recommended dietary therapy of restricting intake of fermentable carbs for irritable bowel syndrome, or IBS for short, have an abundance of particular types of bacteria in their gut, reveals research published online in the journal Gut.

23 Nov 2021

Western diet has high levels of blood lipids associated with systemic inflammation, study finds

Mice fed a diet high in fat, cholesterol and calories, akin to the Western diet, had higher measures of blood lipids associated with elevated levels of inflammation, a new UCLA study finds.

22 Nov 2021

Clearing old, dysfunctional cells in fat alleviates diabetes

Eliminating old, dysfunctional cells in human fat also alleviates signs of diabetes, researchers from UConn Health report. The discovery could lead to new treatments for Type 2 diabetes and other metabolic diseases.

22 Nov 2021

Monitoring cellular metabolism for NAFLD/NASH liver disease research

In this interview, Jolanta Vidugiriene, a Senior Research Scientist at Promega Corporation, talks to News-Medical about tools for studying metabolism in NAFLD/NASH research.

From Promega Corporation 22 Nov 2021

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Researchers recently used bioinformatics analysis techniques to explore the diseases caused by SARS-CoV-2 infection in the human digestive tract.

22 Nov 2021

Researchers use embryonic stem cell model to study genetic architecture in the hypothalamus

A study led by researchers at Children's Hospital of Philadelphia has implicated several genes involved in a variety of bodily functions associated with the hypothalamus, a notoriously difficult-to-study region of the brain.

21 Nov 2021

Researchers discover new link between diet, intestinal stem cells and disease

The intestine is essential for maintaining our energy balance and is a master at reacting quickly to changes in nutrition and nutrient balance.

21 Nov 2021

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic disorder affecting children and adolescents, suggests a study in mice by scientists at the National Institutes of Health.

20 Nov 2021

Short-term severe calorie restriction safe, feasible, and well tolerated by cancer patients

A diet involving short-term, severe calorie restriction was safe, feasible, and resulted in a decrease of blood glucose and growth factor concentration, reduction in peripheral blood immunosuppressive cells, and enhanced intratumor T-cell infiltration in cancer patients receiving standard-of-care therapy, according to the results of a clinical trial.

18 Nov 2021

Northwestern awarded grant to advance equity in biomedical sciences

Northwestern University Feinberg School of Medicine has been awarded a grant from the Walder Foundation via the COVID-19 Fund to Retain Clinical Scientists (FRCS) competition, designed to support policies and practices at U.S. medical schools to advance research productivity and retain early-career clinician investigators experiencing family caregiving challenges due to the COVID-19 pandemic.

17 Nov 2021

Metabolism News and Research

Latest Metabolism News and Research

Neural network 'hallucinates' proteins with new, stable structures

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

Novel anti-inflammatory drug target identified by CRISPR

Scientists discover low amounts of cholesterol in tumor-associated macrophages

Study uncovers new mechanism to explain how obesity jeopardizes the functions of skeletal muscle

Experimental compound reduces diabetic complications in mice

Exosomes involved in the progression of breast cancer in patients with obesity, diabetes

Study reveals distinct gut microbial 'signatures' highly responsive to dietary therapy for IBS

Western diet has high levels of blood lipids associated with systemic inflammation, study finds

Clearing old, dysfunctional cells in fat alleviates diabetes

Monitoring cellular metabolism for NAFLD/NASH liver disease research

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Researchers use embryonic stem cell model to study genetic architecture in the hypothalamus

Researchers discover new link between diet, intestinal stem cells and disease

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Short-term severe calorie restriction safe, feasible, and well tolerated by cancer patients

Northwestern awarded grant to advance equity in biomedical sciences

Study may help predict genomic changes that may happen in advanced cancers based on therapy

Scientists predict structures of eukaryotic protein complexes using AI

Model simulations show no need for DEX dose adjustments in COVID-19 patients with liver disease

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production