Metabolism News and Research

Latest Metabolism News and Research

Long-held theory of cancer-induced immune suppression requires revision, study says

Many cancers produce an enzyme called IDO that suppresses immune system activity, but the long-held hypothesis of how this mechanism operates requires revision, according to a study published in Clinical Cancer Research.

29 Sep 2021

Artificial sweeteners in drinks may increase food cravings and appetite, study reveals

A synthetic aftertaste might not be the only side effect of switching to diet soda, especially if you're trying to lose weight.

28 Sep 2021

People over 40 with type 1 diabetes have worse outcomes from COVID-19, shows study

Adults with type 1 diabetes need to be extra cautious of COVID-19 as they are more likely to be hospitalized and die, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

28 Sep 2021

Research reveals nucleolar RNA interference based on C. elegans as a model organism

A research group led by Prof. GUANG Shouhong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, collaborating with Prof. FENG Xuezhu from the First Affiliated Hospital of USTC, revealed the nucleolar RNA interference based on Caenorhabditis elegans (C. elegans) as a model organism. The study was published in Nuclear Acids Research.

28 Sep 2021

SARS-CoV-2 entry inhibitors show antiviral activity

A new study used a combination of a computer-aided drug design approach and cell-based in vitro assays to identify five potential SARS-CoV-2 inhibitors.

27 Sep 2021

Researchers explore serious impact of obesogens on childhood and adult obesity

Everyday exposure to obesity-promoting chemicals (obesogens) represents a significant risk to public health, and needs stronger regulation to minimize exposure and protect people's health, according to evidence presented today at the 59th Annual European Society for Paediatric Endocrinology Meeting.

25 Sep 2021

Peter Adams and Gerald Shadel receive NIH grant to explore the link between aging and liver cancer

Sanford Burnham Prebys professor Peter D. Adams, Ph.D., who directs the Aging, Cancer and Immuno-oncology Program and Salk Institute professor Gerald Shadel, Ph.D., who directs the San Diego Nathan Shock Center of Excellence in the Basic Biology of Aging, have been awarded a grant from the NIH's National Institute on Aging for $13 million, funding a five-year project to explore the connection between aging and liver cancer.

24 Sep 2021

Researchers discover how Rift Valley fever virus enters cells

Rift Valley fever virus causes economically devastating outbreaks of hemorrhagic fever in livestock such as sheep, goats and cattle.

24 Sep 2021

Early weight loss may protect future fertility of young boys with obesity

Reproductive function in boys with obesity may be improved through weight loss, which could protect their fertility in adulthood, according to research presented today at the 59th Annual European Society for Paediatric Endocrinology Meeting.

23 Sep 2021

Skeletal muscle activity regulates circadian rhythm of the liver

The biological clock/circadian rhythm is the mechanism that ensures that a certain physiological process takes place at a specific time of the day or night.

23 Sep 2021

New analysis reveals the economic burden of polycystic ovary syndrome in the U.S.

The most common hormone disorder affecting women of reproductive age-;polycystic ovary syndrome (PCOS)-;cost an estimated $8 billion to diagnose and treat nationwide in 2020, according to a new economic analysis published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

21 Sep 2021

Researchers uncover a molecular mechanism to inhibit aggravation of colitis

The intestinal microbial ecosystem includes diverse species of bacteria. These bacteria can produce bioactive metabolites that directly affect the host's immune system.

21 Sep 2021

Sunitinib extends progression-free survival in patients with rare neuroendocrine tumor, study shows

The first randomized study in malignant pheochromocytoma and paraganglioma (MPP) has found that sunitinib prolongs progression-free survival (PFS) by more than five months.

20 Sep 2021

Women exposed to high levels of PFAS more likely to stop breastfeeding early

Women with higher levels of PFAS in their system may be 20% more likely to stop breastfeeding early, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

16 Sep 2021

COVID-19 and the gut-lung axis

A new study explores the hypothesis that stimulation of the gut could be responsible for the lung inflammation seen in COVID-19, triggered by SARS-CoV-2.

16 Sep 2021

Study discovers biological mechanism linking long-term arsenic exposure to cancer, diabetes

A University of Arizona Health Sciences study has identified the biological mechanism linking long-term arsenic exposure to diseases such as cancer and Type 2 diabetes.

15 Sep 2021

Scientists investigate if the APOE4 gene in astrocytes relates to Alzheimer's disease

AD, the most frequent cause of dementia, affects an estimated 24 million people worldwide. With very limited treatment options, scientists are looking for ways to understand the disease better.

15 Sep 2021

Drug accumulation alters gut bacterial metabolism and composition

In a research paper recently published in the journal Nature by Klünemann et al. (September 8th, 2021), the interaction of 15 diverse drugs with 25 common strains of gut bacteria is investigated, revealing 70 bacteria-drug interactions that include 29 entirely novel mechanisms not yet reported.

15 Sep 2021

Cholesterol appears to play a key role in the development of Alzheimer’s disease

Cholesterol manufactured in the brain appears to play a key role in the development of Alzheimer's disease, new research indicates.

14 Sep 2021

New method for profiling tissue-specific secretory proteins in live mice

Researchers have presented a method for profiling tissue-specific secretory proteins in live mice. This method is expected to be applicable to various tissues or disease models for investigating biomarkers or therapeutic targets involved in disease progression.

14 Sep 2021

Metabolism News and Research

Latest Metabolism News and Research

Long-held theory of cancer-induced immune suppression requires revision, study says

Artificial sweeteners in drinks may increase food cravings and appetite, study reveals

People over 40 with type 1 diabetes have worse outcomes from COVID-19, shows study

Research reveals nucleolar RNA interference based on C. elegans as a model organism

SARS-CoV-2 entry inhibitors show antiviral activity

Researchers explore serious impact of obesogens on childhood and adult obesity

Peter Adams and Gerald Shadel receive NIH grant to explore the link between aging and liver cancer

Researchers discover how Rift Valley fever virus enters cells

Early weight loss may protect future fertility of young boys with obesity

Skeletal muscle activity regulates circadian rhythm of the liver

New analysis reveals the economic burden of polycystic ovary syndrome in the U.S.

Researchers uncover a molecular mechanism to inhibit aggravation of colitis

Sunitinib extends progression-free survival in patients with rare neuroendocrine tumor, study shows

Women exposed to high levels of PFAS more likely to stop breastfeeding early

COVID-19 and the gut-lung axis

Study discovers biological mechanism linking long-term arsenic exposure to cancer, diabetes

Scientists investigate if the APOE4 gene in astrocytes relates to Alzheimer's disease

Drug accumulation alters gut bacterial metabolism and composition

Cholesterol appears to play a key role in the development of Alzheimer’s disease

New method for profiling tissue-specific secretory proteins in live mice

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production