Metabolism News and Research

Latest Metabolism News and Research

GIST researchers unravel coordination mechanism of base excision repair

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Synthetic molecular code shows promise towards improving immunotherapy response of cancer patients

A synthetic molecular code shows promise towards improving the response of some cancer patients to immunotherapy treatments.

14 Sep 2021

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

In a new study posted to the medRxiv* server scientists from Weil Cornell University and Stony Brook University in New York attempted to identify the metabolic and immune markers associated with severe COVID-19 disease using high-throughput targeted nuclear magnetic resonance (NMR) spectroscopy and high-dimensional flow cytometry. This will facilitate risk stratification, monitoring, and therapeutic interventions in COVID-19 patients.

14 Sep 2021

Carbohydrate-insulin model can better explain obesity and weight gain

Statistics from the Centers for Disease Control and Prevention (CDC) show that obesity affects more than 40% of American adults, placing them at higher risk for heart disease, stroke, type 2 diabetes, and certain types of cancer.

13 Sep 2021

Standing is associated with better insulin sensitivity and metabolic health

Insulin is a key hormone in energy metabolism and blood sugar regulation. Normal insulin function in the body may be disturbed by e.g. overweight, leading to decreased insulin sensitivity and increased risk of developing type 2 diabetes and cardiovascular diseases.

12 Sep 2021

Physical exercise can improve cancer-induced anemia

Many cancer patients suffer from anemia leaving them fatigued, weak, and an impaired ability to perform physical activity.

9 Sep 2021

Optibrium Releases 3D Ligand-based Design Module for StarDrop Drug Discovery Software

Optibrium Ltd today announced the release of the latest version of StarDrop™, its comprehensive software platform for small molecule design.

From Optibrium Ltd. 9 Sep 2021

Restoring beneficial gut microbes to enhance the efficacy of cancer immunotherapy

The gut microbiome-;the collection of bacteria, viruses, fungi, and other microorganisms that reside in our gastrointestinal tracts-;can impact us in a variety of different ways, from our metabolism to our mood.

9 Sep 2021

Study finds accumulation of common therapeutic drugs by gut bacteria

Common medications can accumulate in gut bacteria, a new study has found, altering bacterial function and potentially reducing the effectiveness of the drug.

8 Sep 2021

Understanding platelets in COVID-19 may help identify diagnostic markers and treatments

Researchers in the United States and Japan have provided novel insights into the pathologic mechanisms underlying coronavirus disease 2019 (COVID-19) that may aid the identification of potential diagnostic biomarkers and treatment targets.

8 Sep 2021

Potential pancoronavirus fusion inhibitors that are effective against SARS-CoV-2 variants

A new study successfully identifies a series of inhibitors that possesses pancoronavirus activity against SARS-CoV, SARS-CoV-2, and MERS-CoV.

7 Sep 2021

Researchers find potential new target for treating systemic inflammation in obesity

A study led by researchers at the University of Chicago and Indiana University has determined that a protein called elF5A is necessary for driving inflammation in macrophage cells in obesity.

7 Sep 2021

Newly identified mechanism can accelerate the development of STING-activating drugs using imaging

A new study from scientists at the UCLA Jonsson Comprehensive Cancer Center found that emerging drugs that activate the protein STING, a well-established regulator of immune cell activation, substantially alter the activity of metabolic pathways responsible for generating the nucleotide building blocks for DNA.

7 Sep 2021

New imaging technique uses photonics for early diagnosis of bowel cancer

Early intervention could prevent many of the 160,000 deaths from colon cancer in Europe each year. Colonoscopies, the gold standard for spotting bowel cancer early, can still miss up to 20% of precancerous cells.

7 Sep 2021

Hypopituitarism and COVID-19 – exploring a possible bidirectional relationship?

In a recent study published in Reviews in Endocrine and Metabolic Disorders, the researchers discuss the extra-pulmonary manifestations of COVID-19.

5 Sep 2021

Temperature variations could have driven the division of protocells

A simple mechanism could underlie the growth and self-replication of protocells-;putative ancestors of modern living cells-;suggests a study publishing September 3 in Biophysical Journal.

4 Sep 2021

NIH awards $18.15 million to seven projects focused on interoception

The National Institutes of Health is awarding seven projects a total of $18.15 million over five years to a new effort focused on interoception—the ways in which organisms sense and regulate signals within their bodies.

4 Sep 2021

Growing wheat varieties with biological nitrification inhibition trait could increase yields

An international collaboration has discovered and transferred to elite wheat varieties a wild-grass chromosome segment that causes roots to secrete natural inhibitors of nitrification, offering a way to dial back on heavy fertilizer use for wheat and to reduce the crop's nitrogen leakage into waterways and air, while maintaining or raising its productivity and grain quality, says a new report in the Proceedings of the National Academy of Sciences of the United States of America.

2 Sep 2021

'Forever chemicals' may increase the risk of type 2 diabetes in Latino girls, study finds

A new USC study finds that a class of environmental pollutants known as "forever chemicals" may increase the risk of type 2 diabetes in Latino girls.

1 Sep 2021

Immune cell betrayal makes aging mice less tolerant of cold temperatures

Human evolution has provided us a level of protection from the existential threat of cold temperature with the capacity to produce heat from fat stored in the body.

1 Sep 2021

Metabolism News and Research

Latest Metabolism News and Research

GIST researchers unravel coordination mechanism of base excision repair

Synthetic molecular code shows promise towards improving immunotherapy response of cancer patients

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

Carbohydrate-insulin model can better explain obesity and weight gain

Standing is associated with better insulin sensitivity and metabolic health

Physical exercise can improve cancer-induced anemia

Optibrium Releases 3D Ligand-based Design Module for StarDrop Drug Discovery Software

Restoring beneficial gut microbes to enhance the efficacy of cancer immunotherapy

Study finds accumulation of common therapeutic drugs by gut bacteria

Understanding platelets in COVID-19 may help identify diagnostic markers and treatments

Potential pancoronavirus fusion inhibitors that are effective against SARS-CoV-2 variants

Researchers find potential new target for treating systemic inflammation in obesity

Newly identified mechanism can accelerate the development of STING-activating drugs using imaging

New imaging technique uses photonics for early diagnosis of bowel cancer

Hypopituitarism and COVID-19 – exploring a possible bidirectional relationship?

Temperature variations could have driven the division of protocells

NIH awards $18.15 million to seven projects focused on interoception

Growing wheat varieties with biological nitrification inhibition trait could increase yields

'Forever chemicals' may increase the risk of type 2 diabetes in Latino girls, study finds

Immune cell betrayal makes aging mice less tolerant of cold temperatures

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production