Metabolism News and Research

Latest Metabolism News and Research

Researchers discover a gene family strongly implicated in the development of liver cancer

In a comprehensive analysis of human gene activation data, researchers from the Centenary Institute have discovered that the dipeptidyl peptidase-4 (DPP4) gene family is strongly implicated in the development of human hepatocellular carcinoma (HCC), the most common type of primary liver cancer.

7 Apr 2021

Gut microbiome communicates with horse’s cells to enhance their athletic performance

A horse’s gut microbiome communicates with its host by sending chemical signals to its cells, which has the effect of helping the horse to extend its energy output, finds a new study published in Frontiers in Molecular Biosciences.

7 Apr 2021

New biomarker of glucocorticoid action could help clinicians to tailor treatments

Researchers have uncovered pathways involved in the body's response to glucocorticoid treatments and identified a novel biomarker that could be used to monitor how these drugs work in patients, according to a clinical study published today in eLife.

6 Apr 2021

$10.8 million grant from NIH helps establish Arkansas Integrative Metabolic Research Center

A $10.8 million grant from the National Institutes of Health will enable an interdisciplinary team of researchers at the University of Arkansas and University of Arkansas for Medical Sciences to address the role of cell and tissue metabolism in rare and common diseases such as cancer, diabetes, obesity and mitochondrial disorders.

6 Apr 2021

Targeting microRNAs makes cancer stem cells more susceptible to chemotherapies

Researchers in Italy have identified a pair of microRNA molecules that help maintain a population of cancerous stem cells that drive the growth of breast cancers and initiate tumor relapse after treatment.

3 Apr 2021

Diet and lifestyle may play a significant role in Alzheimer's disease

For years, research to pin down the underlying cause of Alzheimer's Disease has been focused on plaque found to be building up in the brain in AD patients.

2 Apr 2021

HCAs are a promising risk indicator of type 2 diabetes

A series of studies led by researchers from Hong Kong Baptist University have revealed that hyocholic acid and its derivatives (collectively known as HCAs), a component of bile acids that facilitate fat digestion, are a promising risk indicator of type 2 diabetes.

1 Apr 2021

Researchers reveal novel therapeutic target in the treatment of certain cancers

Mount Sinai Researchers Find "Removal of AKAP11 Protein by Autophagy as a key to Fuel Mitochondrial Metabolism and Tumor Cell Growth through activating protein kinase A (PKA) (Patent pending)"

1 Apr 2021

Exposure to endocrine-disrupting chemicals may increase likelihood of postpartum depression

Endocrine-disrupting chemicals may influence hormonal shifts during pregnancy as well as contribute to postpartum depression, according to a small study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

1 Apr 2021

Metabolic dysfunction found in mouse models of neurodevelopmental disorders

Mouse models of neurodevelopmental disorders possess unique, sex-specific metabolic dysfunctions, according to a new study in eNeuro.

1 Apr 2021

Mice study points to a promising treatment for relieving colitis pain without side effects

A targeted opioid that only treats diseased tissues and spares healthy tissues relieves pain from inflammatory bowel disease without causing side effects, according to new research published in the journal Gut.

31 Mar 2021

Study opens door to new approaches for preventing the development of metabolic diseases

The protein Asc-1 regulates whether fat-burning beige or fat-storing white adipocytes are formed, which can have an impact on the development of metabolic diseases.

31 Mar 2021

Scientists discover how Streptococcus pyogenes can obtain nutrition from the skin surface

Streptococcus pyogenes is one of the most important bacterial causes of human skin infections. If S. pyogenes invades deep into the tissue, it can cause life-threatening illnesses, such as sepsis and toxic shock.

31 Mar 2021

Male fetuses impair the maternal and placental immune response to SARS-CoV-2 infection in pregnancy, finds study

The ongoing COVID-19 pandemic, caused by SARS-CoV-2, is now established to be more likely to lead to symptomatic and serious illness in males relative to females. This may extend as far back as pregnancy, suggests a recent study.

31 Mar 2021

Study reveals how exercise during pregnancy confers metabolic health benefits in offspring

A mechanism has been identified that explains how physical exercise in pregnancy confers metabolic health benefits in offspring.

30 Mar 2021

Research consortium identifies cell stress mechanisms for chronic inflammatory liver disease

Primary sclerosing cholangitis (PSC) is a rare, chronic, inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched.

30 Mar 2021

Study explains the link between psoriasis treatment and cardiovascular diseases

Patients with psoriasis, an autoimmune skin disorder, often have cardiovascular disorders as well. Hence, it is important for patients and clinicians to understand how treatments for psoriasis may influence cardiovascular disease risks.

30 Mar 2021

Study reveals the structure of key enzyme that may advance cancer research

In order to develop more effective drugs against a range of cancers, researchers have been investigating the molecular structure of many diseased-linked enzymes in the body. An intriguing case in point is Taspase 1, a type of enzyme known as a protease.

30 Mar 2021

GlyNAC could improve many age-associated defects in older humans

A pilot human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC - a combination of glycine and N-acetylcysteine as precursors of the natural antioxidant glutathione - could improve many age-associated defects in older humans to improve muscle strength and cognition, and promote healthy aging.

29 Mar 2021

Diabetes drug appears to exploit vulnerability of AIDS-causing retrovirus HIV

A team led by scientists at the UNC School of Medicine discovered an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems able to exploit this vulnerability.

29 Mar 2021

Metabolism News and Research

Latest Metabolism News and Research

Researchers discover a gene family strongly implicated in the development of liver cancer

Gut microbiome communicates with horse’s cells to enhance their athletic performance

New biomarker of glucocorticoid action could help clinicians to tailor treatments

$10.8 million grant from NIH helps establish Arkansas Integrative Metabolic Research Center

Targeting microRNAs makes cancer stem cells more susceptible to chemotherapies

Diet and lifestyle may play a significant role in Alzheimer's disease

HCAs are a promising risk indicator of type 2 diabetes

Researchers reveal novel therapeutic target in the treatment of certain cancers

Exposure to endocrine-disrupting chemicals may increase likelihood of postpartum depression

Metabolic dysfunction found in mouse models of neurodevelopmental disorders

Mice study points to a promising treatment for relieving colitis pain without side effects

Study opens door to new approaches for preventing the development of metabolic diseases

Scientists discover how Streptococcus pyogenes can obtain nutrition from the skin surface

Male fetuses impair the maternal and placental immune response to SARS-CoV-2 infection in pregnancy, finds study

Study reveals how exercise during pregnancy confers metabolic health benefits in offspring

Research consortium identifies cell stress mechanisms for chronic inflammatory liver disease

Study explains the link between psoriasis treatment and cardiovascular diseases

Study reveals the structure of key enzyme that may advance cancer research

GlyNAC could improve many age-associated defects in older humans

Diabetes drug appears to exploit vulnerability of AIDS-causing retrovirus HIV

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production