Metabolism News and Research

Latest Metabolism News and Research

Scientists produce biodegradable nanocoating with antimicrobial and anti-reflective properties

Scientists from Russia and Switzerland have probed into nanostructures covering the corneas of the eyes of small fruit flies. Investigating them the team learned how to produce the safe biodegradable nanocoating with antimicrobial, anti-reflective, and self-cleaning properties in a cost-effective and eco-friendly way.

14 Oct 2020

Study summarizes treatment and management of glutaric acidemia type 1

A new study summarizes over 30 years of clinical experience in the treatment and management of glutaric acidemia type 1 (GA1), a rare and potentially devastating metabolic disorder caused by variants in the GCDH gene.

14 Oct 2020

Physical activity in the morning could have a beneficial effect against cancer

One potential cause of cancer is circadian disruption, the misalignment of environmental cues (light, food intake, etc.) and our endogenous circadian rhythms.

13 Oct 2020

Study examines the pharmacogenomics of opioid addiction

In one of the first studies of its kind, a University of Cincinnati researcher is using a grant from the Ohio attorney general's office to research the pharmacogenomics of opioid addiction.

13 Oct 2020

Researchers identify a mechanism to prevent hair loss

An international research group headed by Associate Professor Sara Wickström at the University of Helsinki has identified a mechanism that is likely to prevent hair loss.

13 Oct 2020

Regular moderate physical exercise can significantly reduce cancer risk

Disruption to our circadian rhythms due to a mismatch between environmental influences, such as exposure to light or mealtimes, and our internal 24-hour clock (circadian rhythm) is a possible cause of cancer.

13 Oct 2020

Researchers explore molecular factors that drive the severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

13 Oct 2020

In vitro BA-LRA can help detect small molecule drugs for drug-induced liver injury

BioIVT, a leading provider of research models and services for drug and diagnostic development, today announced the publication of research describing the use of HEPATOPAC® cultures with a targeted in vitro assay to identify small molecule drugs with high potential for drug-induced liver injury (DILI).

13 Oct 2020

Scientists explain why some COVID-19 patients develop neurological symptoms

Now, a new study published on the preprint server bioRxiv sheds light on the mechanism behind brain involvement in the COVID-19 pandemic. A team of researchers at the Krembil Research Institute and the University of Toronto in Canada aimed to understand further the potential mechanisms underlying SARS-CoV-2 tropism for brain vasculature to see how infection occurs in the brain.

13 Oct 2020

Why blood type O might lower risk for SARS-CoV-2 infection

The author hypothesizes that people with non-O blood groups may have highest contact with the SARS-CoV-2 virus via the formation of in intermediate structure, resulting in possibly higher infection rates and more severe symptoms.

12 Oct 2020

Study reveals why immobilization after injury helps in healing

By far, the most common injuries seen in emergency rooms in the United States are those affecting extremities. Immobilization is the most common treatment, and yet, until recently, it was unknown exactly why this technique worked to advance healing.

12 Oct 2020

Powerful antimicrobial molecules engineered from toxic proteins in wasp venom

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered powerful new antimicrobial molecules from toxic proteins found in wasp venom.

12 Oct 2020

Analysis of existing comorbidities and COVID-19 mortality

As the COVID-19 pandemic continues to spread, and research related to potential risk factors for COVID-19 mortality continues, it is becoming clear that individuals with underlying comorbidities have a greater risk of death from COVID-19. The exact contribution of different comorbidities is unclear, however. Now, a new study published in the journal PLOS ONE dissects this topic and may help to quantify the risk posed by specific conditions and offer help with the prognosis.

11 Oct 2020

CHLA investigator receives $3.4 million research grant to study rotavirus vaccine

Rotavirus (RV) is an extremely contagious viral infection and the most common cause of diarrhea in infants and children worldwide.

9 Oct 2020

Exome sequencing sheds light on genetic causes of nonimmune hydrops fetalis

A new study by University of California researchers shows the promise of high-throughput DNA-sequencing technologies to improve prenatal diagnosis and pregnancy outcomes for women who have experienced an abnormal prenatal ultrasound.

8 Oct 2020

Diet and folic acid can influence pregnancy outcomes

Healthy dietary choices are not only important for expectant mothers during the early months of pregnancy but equally important in the months prior to conception.

8 Oct 2020

Vitamin D deficiency may predict COVID-19 seroconversion

A recent study published on the preprint server medRxiv* in October 2020 reports the potential contribution of vitamin D deficiency to an increased risk of COVID-19 in a subset of health care workers in the UK.

8 Oct 2020

Intracellular ATP levels in the cortical neurons vary with sleep–wake states, animal study shows

It is assumed that the brain has homeostatic mechanisms to prevent the depletion of cellular energy, required for all cellular activities.

7 Oct 2020

Researchers create p16-Cre ERT2 -tdTomato mouse model to characterize in vivo senescent cells

Cell senescence is a state of permanent cell cycle arrest that was initially defined for cells grown in cell culture. It plays a key role in age-associated organ dysfunction and age-related diseases such as cancer, but the in vivo pathogenesis is largely unclear.

7 Oct 2020

Researcher receives NIA grant to study traumatic stress-related accelerated cellular aging in the brain

Erika Wolf, PhD, clinical research psychologist for the National Center for PTSD at the VA Boston Healthcare System and associate professor of psychiatry at Boston University School of Medicine, is the recipient of a four-year, $1.7 million R01 award from the National Institute on Aging to study traumatic stress related accelerated cellular aging in the brain.

7 Oct 2020