Metabolism News and Research

Latest Metabolism News and Research

New discovery could help protect the liver from fructose-induced diseases

A team of international researchers including Monash University academics has discovered that, contrary to previous belief, fructose causes liver toxicity by changing the barrier function of the intestine.

27 Aug 2020

AstraZeneca partners with World Heart Federation to reduce the global burden of heart failure

AstraZeneca today announced a new partnership with the leading voice in cardiovascular (CV) health, the World Heart Federation, to drive global action to prevent, control and reduce the burden of CV disease and its associated risks and complications.

From AstraZeneca 27 Aug 2020

New approach to combination drug design could be applied to disease therapies beyond diabetes

Biomedical engineers at Duke University have shown that the efficacy of a two-pronged type 2 diabetes treatment increases when the drugs are linked by a heat-sensitive tether rather than simply concurrently administered.

27 Aug 2020

New group of Chlamydiae have hydrogen-producing genes that help them survive without oxygen

An international team of researchers has discovered a new group of Chlamydiae - Anoxychlamydiales - living under the ocean floor without oxygen.

27 Aug 2020

Study offers hope for treatment of Krabbe disease

In one out of 100,000 infants, a mutation in the GALC gene causes an incurable, always fatal disorder known as infantile Krabbe disease, or globoid cell leukodystrophy. Most children with the condition die before they turn 2.

26 Aug 2020

Novel cell-based therapy holds promise for obesity and diabetes

Obesity is the main cause of type 2 diabetes and related chronic illnesses that together will kill more people around the globe this year than the Covid-19 coronavirus.

26 Aug 2020

Researchers identify how promising therapy may work to improve adverse effects of NAFLD

A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease (NAFLD), the most common form of chronic liver disease.

26 Aug 2020

Study reveals a troubling connection between coronavirus and obesity

A review of COVID-19 studies reveals a troubling connection between two health crises: coronavirus and obesity.

26 Aug 2020

Advances in Virus Epigenetics

Growing evidence shows viruses exploit epigenetic processes to control their life cycles but epigentic regulation of viral infections is not fully understood.

From Chromatrap® - Porvair Sciences Ltd 25 Aug 2020

Study examines potential therapeutic approach for Alzheimer's disease

Research looking at a possible new therapeutic approach for Alzheimer's disease was recently published in the Journal of Neuroinflammation.

25 Aug 2020

New approach involves "antivitamins" to develop new classes of antibiotics

Antibiotics are among the most important discoveries of modern medicine and have saved millions of lives since the discovery of penicillin almost 100 years ago.

25 Aug 2020

Excessive fructose consumption can result in non-alcoholic fatty liver disease

Excessive consumption of fructose -; a sweetener ubiquitous in the American diet -; can result in non-alcoholic fatty liver disease (NAFLD), which is comparably abundant in the United States.

24 Aug 2020

RNA-targeting compound restarts a healing factor silenced by heart attack

A heart attack can leave parts of the heart permanently scarred and stiff, resulting in prolonged disability and potential progression toward heart failure. Scientists have studied various ways to repair or regenerate such damaged heart tissue, with limited success.

24 Aug 2020

$Prolonged use of bisphosphonates increases risk of atypical femur fractures$

Prolonged use of bisphosphonates increases risk of atypical femur fractures

The risk of atypical femur fractures increases with prolonged use of bisphosphonates, drugs commonly used to treat osteoporosis, according to a new study.

24 Aug 2020

Congenital disorder of fat metabolism can cause chronic hyperreaction of the immune system

Scientists at the University of Bonn identify previously unknown disease mechanism. A congenital disorder of the fat metabolism can apparently cause chronic hyperreaction of the immune system.

24 Aug 2020

Study: Frequent use of antimicrobial drugs impairs bacterial diversity in saliva

The strongest associations were presented with azithromycin that is used for example to middle ear infections, strep throat and pneumonia.

24 Aug 2020

Developing more precise, targeted therapy for a highly aggressive breast cancer

Taking advantage of a cancer cell's altered metabolism that drives its runaway growth, Princess Margaret researchers are zeroing in on these molecular changes to help them develop more precise drug targets for one of the most deadly breast cancers.

21 Aug 2020

Dusp8 protein has regulatory effects on hypothalamic insulin sensitivity

The brain plays a major role in controlling our blood glucose levels. In type 2 diabetics this glucose metabolism brain control is often dysfunctional. Genetic components for this phenomenon have so far remained elusive.

21 Aug 2020

Study could reveal brain cells and circuits that influence human health and metabolism in response to dietary changes

A new federally funded study could reveal the nervous system cells and circuits in our brains that influence our metabolism and health in response to dietary changes.

21 Aug 2020

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

A new study published on the preprint server bioRxiv* in August 2020 presents a cynomolgus macaque model that develops symptomatic SARS-CoV-2 infection in a mild form, with low or no antibody responses, making it suitable to study human responses to vaccines and drugs targeting the virus.

21 Aug 2020

Metabolism News and Research

Latest Metabolism News and Research

New discovery could help protect the liver from fructose-induced diseases

AstraZeneca partners with World Heart Federation to reduce the global burden of heart failure

New approach to combination drug design could be applied to disease therapies beyond diabetes

New group of Chlamydiae have hydrogen-producing genes that help them survive without oxygen

Study offers hope for treatment of Krabbe disease

Novel cell-based therapy holds promise for obesity and diabetes

Researchers identify how promising therapy may work to improve adverse effects of NAFLD

Study reveals a troubling connection between coronavirus and obesity

Advances in Virus Epigenetics

Study examines potential therapeutic approach for Alzheimer's disease

New approach involves "antivitamins" to develop new classes of antibiotics

Excessive fructose consumption can result in non-alcoholic fatty liver disease

RNA-targeting compound restarts a healing factor silenced by heart attack

Prolonged use of bisphosphonates increases risk of atypical femur fractures

Congenital disorder of fat metabolism can cause chronic hyperreaction of the immune system

Study: Frequent use of antimicrobial drugs impairs bacterial diversity in saliva

Developing more precise, targeted therapy for a highly aggressive breast cancer

Dusp8 protein has regulatory effects on hypothalamic insulin sensitivity

Study could reveal brain cells and circuits that influence human health and metabolism in response to dietary changes

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production