Metabolism News and Research

Latest Metabolism News and Research

Medical teams need to be extra vigilant when dealing with diabetics during COVID-19 pandemic

Doctors need to pay particular attention to patients with endocrine disorders and diabetes mellitus in relation to COVID-19 infections, say leading endocrinologists.

2 Apr 2020

Hereditary genetic defect linked to medulloblastoma destabilizes protein regulation

The causes of 40 percent of all cases of certain medulloblastoma - dangerous brain tumors affecting children - are hereditary.

1 Apr 2020

Understanding hereditary medulloblastomas in children

This is a combined press release between EMBL, the Hopp Children's Cancer Center Heidelberg and the German Cancer Consortium.

1 Apr 2020

Study reveals how hormone leptin contributes to weight loss

Some call it baby fat. But recent research has shown that adults have it too--which is a good thing. Brown fat, the so-called good fat that can protect against obesity and associated health risks, like cardiovascular disease and diabetes, is located in small pockets throughout the body.

31 Mar 2020

Individuals taking glucocorticoids are at high risk if infected with COVID-19

Individuals taking a class of steroid hormones called glucocorticoids for conditions such as asthma, allergies and arthritis on a routine basis may be unable to mount a normal stress response and are at high risk if they are infected with the virus causing COVID-19, according to a new editorial published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

31 Mar 2020

Working too many hours may lead to an underactive thyroid

A new study has found that people who work longer hours are more likely to have an underactive thyroid or hypothyroidism.

31 Mar 2020

Evinacumab drug reduces cholesterol levels in patients with rare cholesterol disorder

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol to near-normal levels among patients with a rare cholesterol disorder, meeting the primary endpoint in the first randomized placebo-controlled trial of the drug, which is being presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC).

31 Mar 2020

Clinical trial using genetic testing to guide antiplatelet therapy post-PCI falls short of stated goal

An international clinical trial that used genetic testing to guide which antiplatelet medication was given to patients following percutaneous coronary intervention (PCI) did not meet its stated goal for cutting in half the incidence of serious adverse cardiovascular events, such as heart attack and stroke, in the year following the procedure.

30 Mar 2020

TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

Results from two subgroup analyses of the Phase IV independent TWILIGHT trial funded by AstraZeneca showed Brilinta (ticagrelor) monotherapy reduced the risk of clinically relevant bleeding over 12 months compared to aspirin plus Brilinta in high-risk coronary patients.

From AstraZeneca 30 Mar 2020

Research could open up new therapeutic strategies for some lung and kidney cancers

New findings from researchers at The University of Texas MD Anderson Cancer Center about how some cancer cells become "addicted" to glucose could open up fresh approaches to therapy strategies for cancers with high levels of an amino acid transporter called solute carrier family 7 member 11 (SLC7A11).

30 Mar 2020

Scientists model human CMV-induced microcephaly using brain organoids

A City of Hope scientist is one step closer to discovering what weakens a pathogen that appears to cause babies to be born with abnormally small heads.

30 Mar 2020

Weakness in lung and kidney cancer cells could serve as therapeutic target

An important discovery about how some cancers rely on glucose to survive could lead to development of tumor-specific treatments.

30 Mar 2020

Study shows how copper boosts pig growth

Pigs have better feed conversion rates with copper in their diets, but until now, scientists didn't fully understand why.

27 Mar 2020

Rheumatism: New clues about the prevalence of certain genetic profile in Europeans

A piece of research by the Human Evolutionary Biology Group at the UPV/EHU-University of the Basque Country provides clues about the prevalence of a certain genetic profile in the European population.

27 Mar 2020

Fast-acting anti-malarial compound shows promise in first clinical trial

A fast-acting anti-malarial compound discovered at St. Jude Children's Research Hospital was well tolerated and showed promising anti-malarial effects in the first study in humans.

27 Mar 2020

Factors causing childhood obesity differ for wealthier and poorer countries

Childhood obesity is not just a public health concern in western countries; it is rising across the world, particularly in poor and low-income countries.

26 Mar 2020

Roscovitine enhances nuclear enrichment of traditionally cytoplasmic signaling molecules

Oncotarget Volume 11, Issue 12 reported that using the HL-60 human non-APL AML model where ATRA causes nuclear enrichment of c-Raf that drives differentiation/G0-arrest, the research team now observe that roscovitine enhanced nuclear enrichment of certain traditionally cytoplasmic signaling molecules and enhanced differentiation and cell cycle arrest.

26 Mar 2020

Metabolism News and Research

Latest Metabolism News and Research

Medical teams need to be extra vigilant when dealing with diabetics during COVID-19 pandemic

Hereditary genetic defect linked to medulloblastoma destabilizes protein regulation

Understanding hereditary medulloblastomas in children

Study reveals how hormone leptin contributes to weight loss

Individuals taking glucocorticoids are at high risk if infected with COVID-19

Working too many hours may lead to an underactive thyroid

Evinacumab drug reduces cholesterol levels in patients with rare cholesterol disorder

Clinical trial using genetic testing to guide antiplatelet therapy post-PCI falls short of stated goal

TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

Research could open up new therapeutic strategies for some lung and kidney cancers

Scientists model human CMV-induced microcephaly using brain organoids

Weakness in lung and kidney cancer cells could serve as therapeutic target

Study shows how copper boosts pig growth

Rheumatism: New clues about the prevalence of certain genetic profile in Europeans

Fast-acting anti-malarial compound shows promise in first clinical trial

Factors causing childhood obesity differ for wealthier and poorer countries

Roscovitine enhances nuclear enrichment of traditionally cytoplasmic signaling molecules

Removing a gene prevents Type 1 diabetes in mice by disguising beta cells

Deleting a gene prevents Type 1 diabetes in mice by disguising insulin-producing cells

Why Primary Cells Are Important for In Vitro ADME-Tox Studies

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production