Metabolism News and Research

Latest Metabolism News and Research

Changes in cellular degradation hubs can lead to cancer

A team of scientists at Uppsala University has revealed that alterations in cells’ lysosomes underly abnormal cell growth.

17 Mar 2020

Scientists use artificial intelligence to create new proteins unseen in nature

Researchers have presented a artificial intelligence method for developing new proteins that have never been seen in nature.

17 Mar 2020

$Vitamin D increases chances of regaining mobility after hip fracture$

Vitamin D increases chances of regaining mobility after hip fracture

Senior citizens who are not vitamin D deficient have a better chance of walking after hip fracture surgery, according to a Rutgers-led study.

17 Mar 2020

Key antibiotic used for treating drug-resistant TB does not work as expected

Crick and Imperial researchers have found that a key antibiotic widely used to treat drug-resistant tuberculosis does not work as expected - a finding which could be used to develop new drugs.

16 Mar 2020

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Preclinical trials indicate that a drug candidate called OxaliTex can stop the growth of cancer cells completely. OxaliTex appears to be more potent than many other common chemotherapy drugs, with less toxicity and less rapidly counteracted by mechanisms of drug resistance. The study was reported in the journal Proceedings of the National Academy of Sciences in March 2020.

16 Mar 2020

Single-drug therapy can attack several cellular targets using different modes of action

Clinicians combat the drug resistances of some cancer types by using a combination of different drugs. To make this approach more effective, chemists have designed a chemical conjugate that can simultaneously attack several cellular targets using different modes of action.

13 Mar 2020

Immunosuppressive therapy does not increase risk of vulvar or vaginal cancer in women with IBD

In a new retrospective study, researchers found that the use of immunosuppressive therapy does not increase the occurrence or recurrence of vulvar or vaginal cancer in women with inflammatory bowel disease (IBD).

11 Mar 2020

Aging and competition for nutrients determine changes in gut bacteria

Two studies with surprising discoveries: in the elderly, the bacterium E. coli evolves in a way that can become potentially pathogenic and increase the risk of disease and, according to data obtained in another study, the metabolism of the same bacterium present in the microbiota evolves differently if it is alone or accompanied by other bacteria.

11 Mar 2020

Characterization of novel L-fucose metabolism pathway in anaerobic bacteria

The genetic context in bacterial genomes and screening for potential substrates can help identify the biochemical functions of bacterial enzymes.

11 Mar 2020

Popular painkiller may have more significant effects on the liver than expected

The popular painkiller ibuprofen may have more significant effects on the liver than previously thought, according to new research from the University of California, Davis.

11 Mar 2020

Researchers visualize first structure of key enzyme that helps make triglycerides

The first structure of a lipin enzyme, which carries out an important step in the production of triglycerides, the main reservoir for long-term energy storage, will help scientists to better understand how lipins regulate the production of triglycerides.

11 Mar 2020

Study uncovers novel relationships between SLCs and cytotoxic drugs in human cells

Solute carriers represent the largest family of transmembrane transporters in the human genome, with over 400 members arranged into 65 families.

9 Mar 2020

Bacteria may be involved in the development of type 2 diabetes, study shows

Bacteria may be involved in the development of type 2 diabetes, according to a study published today in Nature Metabolism by researchers from Université Laval, the Québec Heart and Lung Institute, and McMaster University.

9 Mar 2020

New discovery could lead to better strategies for preventing breast cancer metastasis

New discovery in breast cancer could lead to better strategies for preventing the spread of cancer cells to other organs in the body, effectively reducing mortality in breast cancer patients.

8 Mar 2020

Microbiome research uncovers new form of antibiotic tolerance

Antibiotics can make easy work of infections. But how do they affect the complex ecosystems of friendly bacteria that make up our microbiome?

5 Mar 2020

Fatty nutrients control certain neurons in the reward circuit

Energy-dense food, obesity and compulsive food intake bordering addiction: the scientific literature has been pointing to connections between these for years.

5 Mar 2020

City Of Hope builds cloud-based data commons platform for observational study

A $12 million federal grant enabled City of Hope and collaborators to deploy a novel cloud-computing platform, making an immense amount of data from a historic 25-year study more accessible and user-friendly.

5 Mar 2020

Yale discovery has implications for treatment of diabetes and non-alcoholic fatty liver disease

Many health problems in the developed world stem from the disruption of a delicate metabolic balance between glucose production and energy utilization in the liver.

4 Mar 2020

A new, promising method for developing drugs that target, block macropinocytosis

With drug resistance a major challenge in the fight against cancer, a discovery by University of California, Irvine biologists could offer new approaches to overcoming the obstacle.

3 Mar 2020

UAB research reveals hydrogen sulfide as new culprit for deadly tuberculosis

A new culprit -- hydrogen sulfide -- has been found for the deadly infectious disease tuberculosis. Hydrogen sulfide gas is known for its rotten egg smell, yet it has normal physiological roles in the human body to communicate among cells.

3 Mar 2020

Metabolism News and Research

Latest Metabolism News and Research

Changes in cellular degradation hubs can lead to cancer

Scientists use artificial intelligence to create new proteins unseen in nature

Vitamin D increases chances of regaining mobility after hip fracture

Key antibiotic used for treating drug-resistant TB does not work as expected

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Single-drug therapy can attack several cellular targets using different modes of action

Immunosuppressive therapy does not increase risk of vulvar or vaginal cancer in women with IBD

Aging and competition for nutrients determine changes in gut bacteria

Characterization of novel L-fucose metabolism pathway in anaerobic bacteria

Popular painkiller may have more significant effects on the liver than expected

Researchers visualize first structure of key enzyme that helps make triglycerides

Study uncovers novel relationships between SLCs and cytotoxic drugs in human cells

Bacteria may be involved in the development of type 2 diabetes, study shows

New discovery could lead to better strategies for preventing breast cancer metastasis

Microbiome research uncovers new form of antibiotic tolerance

Fatty nutrients control certain neurons in the reward circuit

City Of Hope builds cloud-based data commons platform for observational study

Yale discovery has implications for treatment of diabetes and non-alcoholic fatty liver disease

A new, promising method for developing drugs that target, block macropinocytosis

UAB research reveals hydrogen sulfide as new culprit for deadly tuberculosis

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production