Metabolism News and Research

Latest Metabolism News and Research

Ketone body β-hydroxybutyrate restores protein balance and targets Alzheimer’s-linked aggregates

Scientists identify β-hydroxybutyrate as a key regulator of protein solubility, offering a novel pathway to combat neurodegeneration in aging and Alzheimer’s disease.

4 Dec 2024

ACMG sets new lifelong guidelines for managing phenylalanine hydroxylase deficiency

Updated evidence-based clinical guidelines for phenylalanine hydroxylase deficiency diagnosis and management.

4 Dec 2024

Aging reduces cancer risk by limiting cell regeneration

When it comes to cancer, aging is a double-edged sword, researchers are increasingly learning.

4 Dec 2024

College students’ loneliness outweighs screen time in causing insomnia

Being lonely is a bigger hurdle to a good night's sleep for college students than too much time at a computer or other electronic screen, a new study by Oregon State University suggests.

4 Dec 2024

Fructose consumption linked to accelerated tumor growth in cancer models

Fructose consumption has increased considerably over the past five decades, largely due to the widespread use of high-fructose corn syrup as a sweetener in beverages and ultra-processed foods.

4 Dec 2024

Scientists uncover coffee's surprising effect on gut microbiota

Scientists reveal that coffee consumption influences gut microbiota composition, with a strong link to the bacterium Lawsonibacter asaccharolyticus, independent of caffeine.

3 Dec 2024

Study finds no impact of high vitamin D doses on type 2 diabetes prevention

Using significantly higher doses of vitamin D than recommended for five years did not affect the incidence of type 2 diabetes in elderly men and women, according to a new study from the University of Eastern Finland.

3 Dec 2024

Gut microbes may have helped human ancestors develop larger brains

Brain tissue is among the most energetically costly in the body, and as a result, larger-brained mammals require more energy to support brain growth and maintenance.

3 Dec 2024

Ketone metabolism redefines protein quality control in aging brains

Ketone bodies, produced by the body to provide fuel during fasting, have roles in regulating cellular processes and aging mechanisms beyond energy production. Research at the Buck Institute shows that ketone bodies can best be understood as powerful signaling metabolites affecting brain function in aging and Alzheimer's disease.

3 Dec 2024

New insights into anti-seizure medications during pregnancy

Two common antiseizure medications, lamotrigine and levetiracetam, are safe to use during pregnancy, according to a Stanford Medicine-led study.

3 Dec 2024

Fas-p53 pathway drives metabolic dysfunction and obesity-linked insulin resistance

Researchers unveil Fas-p53 axis as a key regulator in adipocyte metabolism, linking it to obesity and insulin sensitivity through energy expenditure and inflammation pathways.

3 Dec 2024

Spatial transcriptomics uncovers new treatment paths for triple-negative breast cancer

Study uses spatial transcriptomics to map intratumoral heterogeneity and microenvironmental dynamics in triple-negative breast cancer (TNBC). The findings identify nine spatial archetypes and gene signatures linked to immunotherapy response and patient outcomes.

2 Dec 2024

Women with premature ovarian insufficiency face higher risk of autoimmune diseases

Research reveals a significant association between premature ovarian insufficiency and autoimmune diseases, highlighting hypothyroidism as a common condition.

2 Dec 2024

IL-15 improves the effectiveness of GPC3 CAR T cells in targeting solid tumors

The study reveals IL-15's role in enhancing GPC3 CAR T cell therapy, improving tumor targeting and T cell survival in patients with solid cancers.

2 Dec 2024

Natural polyphenol boosts mitochondrial function and muscle performance during aging

Oleuropein enhances mitochondrial calcium uptake, reversing age-related declines in muscle function and energy metabolism, with promising clinical potential.

2 Dec 2024

Gut transit time and pH shape microbiome individuality and dietary responses

Scientists reveal gut transit time and pH as key drivers of microbiome and metabolic individuality, paving the way for personalized dietary strategies.

1 Dec 2024

Phase 1 study finds serine- and glycine-free diet boosts immune response in colorectal cancer

Findings indicate a serine/glycine-free diet can reduce colorectal cancer growth and enhance immune response, offering insights for immunotherapy strategies.

29 Nov 2024

RNA enzyme found key to heart cell energy shift after birth

Researchers investigate the influence of Mettl1 on energy metabolism and the maturation of heart cells after birth.

29 Nov 2024

Research sheds light on how fat cells safely enlarge to store energy

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Professor Miguel Ángel del Pozo Barriuso, who heads the Mechanoadaptation and Caveolae Biology group at the CNIC, has identified an essential mechanism in fat cells (adipocytes) that enables them to enlarge safely to store energy.

28 Nov 2024

Flaws in study design may limit detection of cognitive effects in diet trials

Researchers review the role of diet in preventing cognitive decline and dementia.

28 Nov 2024

Metabolism News and Research

Latest Metabolism News and Research

Ketone body β-hydroxybutyrate restores protein balance and targets Alzheimer’s-linked aggregates

ACMG sets new lifelong guidelines for managing phenylalanine hydroxylase deficiency

Aging reduces cancer risk by limiting cell regeneration

College students’ loneliness outweighs screen time in causing insomnia

Fructose consumption linked to accelerated tumor growth in cancer models

Scientists uncover coffee's surprising effect on gut microbiota

Study finds no impact of high vitamin D doses on type 2 diabetes prevention

Gut microbes may have helped human ancestors develop larger brains

Ketone metabolism redefines protein quality control in aging brains

New insights into anti-seizure medications during pregnancy

Fas-p53 pathway drives metabolic dysfunction and obesity-linked insulin resistance

Spatial transcriptomics uncovers new treatment paths for triple-negative breast cancer

Women with premature ovarian insufficiency face higher risk of autoimmune diseases

IL-15 improves the effectiveness of GPC3 CAR T cells in targeting solid tumors

Natural polyphenol boosts mitochondrial function and muscle performance during aging

Gut transit time and pH shape microbiome individuality and dietary responses

Phase 1 study finds serine- and glycine-free diet boosts immune response in colorectal cancer

RNA enzyme found key to heart cell energy shift after birth

Research sheds light on how fat cells safely enlarge to store energy

Flaws in study design may limit detection of cognitive effects in diet trials

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey