Metabolism News and Research

Latest Metabolism News and Research

PHD2-knockdown overcomes breast cancer cell death in response to glucose starvation

B55α is one of the regulatory subunits of the PP2A phosphatase. This phosphatases has been associated to the control of many biological functions but the multiplicity of complexes that can be formed by the combination of different subunits renders this protein hard in its understanding.

22 Mar 2017

Genotype-guided warfarin dosing linked to reduced risk of adverse events

Using genetic testing to help personalize doses of warfarin therapy given to patients undergoing elective orthopedic surgery appears to lower the risk of combined adverse events compared with clinically guided dosing, according to research presented at the American College of Cardiology's 66th Annual Scientific Session.

21 Mar 2017

Circadian misalignments may favor diabetes development

Like almost all light-sensitive living beings, human beings follow biological rhythms set on a period of about 24 hours.

20 Mar 2017

Fat cells take over production of uridine from liver during fasting

How do mammals keep two biologically crucial metabolites in balance during times when they are feeding, sleeping, and fasting? The answer may require rewriting some textbooks.

17 Mar 2017

Why don’t patients always discuss hyperglycemia with their doctor?

Hyperglycemia occurs when a patient has higher than normal blood sugar levels. If the levels are very high, consistently 13-14 or above, the patient will start to feel tired, thirsty and feel the urge to go to the toilet frequently to pass urine (micturition).

17 Mar 2017

Study: Phthalate exposure during early pregnancy can alter hormone levels in developing fetuses

Exposure during early pregnancy to some phthalates—man-made chemicals commonly found in household plastics, food and personal care products—can have adverse impacts on developing fetuses, according to a new study led by Dr. Sheela Sathyanarayana, a pediatric environmental health specialist at Seattle Children's Research Institute and associate professor at the University of Washington.

16 Mar 2017

Type 2 diabetes can be reversed with intensive medical treatment, study shows

Type 2 diabetes can be reversed with intensive medical treatment using oral medications, insulin and lifestyle therapies, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

15 Mar 2017

VUMC’s Undiagnosed Diseases Network solves medical mysteries using advanced technologies

It's human nature to need answers. Patients with debilitating symptoms need a diagnosis — somewhere to place the blame, a starting point to search for answers.

14 Mar 2017

Novel androgens play major role in development of PCOS, research shows

Scientists led by the University of Birmingham have discovered that a new class of male sex hormones known as androgens plays a key role in the development of polycystic ovary syndrome (PCOS).

13 Mar 2017

New approach shows promise to prevent, treat cholesterol gallstone disease

According to current estimates, 20 to 25 million Americans have or will develop gallstones, representing almost 15% of adults. Although only a small percentage of individuals with gallstones develop symptoms, more than 700,000 individuals annually undergo surgical gallbladder removal and many more take medications to manage the condition or undergo stone-dissolving procedures.

13 Mar 2017

Seven facts about malignant hyperthermia that can help avoid dangerous consequences during surgery

When general anesthesia is required for surgery or another procedure, a patient's care team must be ready for anything—especially the rare, life-threatening syndrome known as malignant hyperthermia.

13 Mar 2017

New study aims to better define which type 2 diabetes patients benefit most from gastric surgery

Bariatric surgery can reverse type 2 diabetes in severely obese people, reducing or eliminating the need for medications, and improve other serious health problems such as high blood pressure and sleep apnea, but it still remains to be determined which patients with type 2 diabetes will benefit most from surgery.

13 Mar 2017

Endostatin can decrease proliferation of castration-resistant prostate cancer cells

Failure of hormone deprivation therapy, which is used to slow prostate cancer in patients, leads to castration-resistant prostate cancer, a lethal form of advanced disease with limited treatment options.

10 Mar 2017

Mayo Clinic study: High-intensity aerobic exercise can reverse cellular aspects of aging

Everyone knows that exercise is good for you, but what type of training helps most, especially when you're older -- say over 65? A Mayo Clinic study says it's high-intensity aerobic exercise, which can reverse some cellular aspects of aging. The findings appear in Cell Metabolism.

10 Mar 2017

Stony Brook researchers discover novel metabolic pathway of lipid ceramide involved in cell death

A collaborative Stony Brook University research team has discovered a novel metabolic pathway of the lipid ceramide, which is involved in cell death.

10 Mar 2017

Scientists uncover Achilles' heel in unique kind of immune memory cells

The capacity for memory isn't exclusive to the brain. The immune system, with its sprawling network of diverse cell types, can recall the pathogens it meets, helping it to swiftly neutralize those intruders upon future encounters.

10 Mar 2017

Scientists pinpoint key biological mechanism that can prevent proliferation of insulin-producing cells

If you become resistant to insulin, a condition that is a precursor to type 2 diabetes, your body tries to compensate by producing more of the "beta" cells in the pancreas that produce the critical hormone.

9 Mar 2017

Timing of carbohydrate intake plays role in blood glucose regulation for men with prediabetes

According to a nutrition study led by the German Institute of Human Nutrition, a partner of the German Center for Diabetes Research, the so-called internal clock also influences how people with impaired glucose metabolism react to carbohydrate-rich food.

9 Mar 2017

Hormone secreted by bone cells can suppress appetite, mice study reveals

A hormone secreted by bone cells can suppress appetite, according to mouse studies conducted by Columbia University Medical Center researchers.

8 Mar 2017

Vitamin C can be used to target and kill cancer stem cells, research finds

Researchers measure the impact on cancer stem cell metabolism of 3 natural substances, 3 experimental pharmaceuticals and 1 clinical drug.

8 Mar 2017

Metabolism News and Research

Latest Metabolism News and Research

PHD2-knockdown overcomes breast cancer cell death in response to glucose starvation

Genotype-guided warfarin dosing linked to reduced risk of adverse events

Circadian misalignments may favor diabetes development

Fat cells take over production of uridine from liver during fasting

Why don’t patients always discuss hyperglycemia with their doctor?

Study: Phthalate exposure during early pregnancy can alter hormone levels in developing fetuses

Type 2 diabetes can be reversed with intensive medical treatment, study shows

VUMC’s Undiagnosed Diseases Network solves medical mysteries using advanced technologies

Novel androgens play major role in development of PCOS, research shows

New approach shows promise to prevent, treat cholesterol gallstone disease

Seven facts about malignant hyperthermia that can help avoid dangerous consequences during surgery

New study aims to better define which type 2 diabetes patients benefit most from gastric surgery

Endostatin can decrease proliferation of castration-resistant prostate cancer cells

Mayo Clinic study: High-intensity aerobic exercise can reverse cellular aspects of aging

Stony Brook researchers discover novel metabolic pathway of lipid ceramide involved in cell death

Scientists uncover Achilles' heel in unique kind of immune memory cells

Scientists pinpoint key biological mechanism that can prevent proliferation of insulin-producing cells

Timing of carbohydrate intake plays role in blood glucose regulation for men with prediabetes

Hormone secreted by bone cells can suppress appetite, mice study reveals

Vitamin C can be used to target and kill cancer stem cells, research finds

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications