Metabolism News and Research

Latest Metabolism News and Research

'Human knockouts': Genetics in families reveals basic biology and possible therapeutics for disorders

More than 1,800 individuals carrying loss-of-function mutations in both copies of their genes, so-called "human knockouts," are described in the first major study to be published in Nature this week by an international collaboration led by the Perelman School of Medicine at the University of Pennsylvania and colleagues.

12 Apr 2017

Scientists discover how insulin-producing cells show differences in age

Diabetes researchers have puzzled for decades about why insulin-producing beta cells in one pancreatic islet often look and behave quite differently than their counterparts in the same islet or in nearby islets.

12 Apr 2017

Study may provide insight into how R-LA promotes death of hepatoma cells

A new study that measured metabolite levels over time in starved rat liver cancer cells showed that treatment with a form of alpha-lipoic acid (LA) inhibited glucose uptake and glycolysis, and led to decreased cellular glucose production from non-carbohydrate sources, which may help explain how the naturally occurring R enantiomeric form of LA (R-LA) promotes the death of hepatoma cells.

12 Apr 2017

TSRI scientists find new way to make cell population resistant to HIV

Scientists at The Scripps Research Institute have found a way to tether HIV-fighting antibodies to immune cells, creating a cell population resistant to the virus.

11 Apr 2017

Metabolite produced by intestinal bacteria protects against type 2 diabetes, study shows

A high concentration of indolepropionic acid in the serum protects against type 2 diabetes, shows a new study from the University of Eastern Finland. Indolepropionic acid is a metabolite produced by intestinal bacteria, and its production is boosted by a fibre-rich diet.

11 Apr 2017

Feeding status alters the human adipose tissue response to exercise, study reveals

Time and again, fitness enthusiasts have a question–to exercise before or after breakfast. A new study published online in the American Journal of Physiology—Endocrinology and Metabolism has highlighted the role of fat toward metabolism. This is the first study that reveals the effects of fasting and feed status on human adipose tissue responses to exercise.

11 Apr 2017

Salk Institute receives additional $3 million Glenn Foundation gift to continue aging research

The Salk Institute has received a $3 million gift from the Glenn Foundation for Medical Research for the second time in 4 years, enabling the Institute to continue investigating the biology of normal human aging and age-related diseases.

10 Apr 2017

Gene CRY1 variant alters circadian clock contributing to delayed sleep phase disorder, study finds

If all your life, you have been functioning best in the evening and night compared to the mornings, a gene mutation may be a reason.

10 Apr 2017

Study highlights different roles of fat in powering and responding to exercise

Exercise enthusiasts often wonder whether it's better to eat or fast before a workout. A new study is the first of its kind to show the effects of eating versus fasting on gene expression in adipose (fat) tissue in response to exercise.

7 Apr 2017

Bielefeld University launches five new medical research projects

Bielefeld University is strengthening its cooperations in medical research. In five new projects, scientists at the university are cooperating with the University hospitals of the Ruhr University of Bochum in the Ostwestfalen-Lippe region.

7 Apr 2017

Endocrine Society’s new Scientific Statement offers guidance to spot hormonal causes of hypertension

A new Scientific Statement issued by the Endocrine Society advises healthcare providers on ways to spot hormonal causes of high blood pressure that can be cured with surgery or treated effectively with medication.

6 Apr 2017

Synthetic biologists engineer gut bacteria capable of sensing colitis

Synthetic biologists at Rice University have engineered gut bacteria capable of sensing colitis, an inflammation of the colon, in mice.

6 Apr 2017

HIIT increases glucose metabolism and insulin sensitivity in diabetics, research reveals

New research reveals that high-intensity interval training (HIIT) increases glucose metabolism in muscles as well as insulin sensitivity in type 2 diabetes. Already after a two-week training period, the glucose uptake in thigh muscles returned to a normal level.

6 Apr 2017

Are we sleeping less than we used to?

There's no solid evidence that we sleep fewer hours today than we ever did, this is something I have gone into large amounts of detail in my book, in my published papers and at a recent meeting at the Royal Society of Medicine.

6 Apr 2017

Overall balance of bacteria on skin may be key factor for acne development

Researchers, led by Dr Huiying Li, an associate professor of molecular and medical pharmacology at the David Geffen School of Medicine at UCLA, used over-the-counter pore cleansing strips to obtain skin follicle samples from 72 individuals: 38 with acne and 34 who didn't have the disease.

6 Apr 2017

Metabolism News and Research

Latest Metabolism News and Research

'Human knockouts': Genetics in families reveals basic biology and possible therapeutics for disorders

Scientists discover how insulin-producing cells show differences in age

Study may provide insight into how R-LA promotes death of hepatoma cells

TSRI scientists find new way to make cell population resistant to HIV

Metabolite produced by intestinal bacteria protects against type 2 diabetes, study shows

Feeding status alters the human adipose tissue response to exercise, study reveals

Salk Institute receives additional $3 million Glenn Foundation gift to continue aging research

Gene CRY1 variant alters circadian clock contributing to delayed sleep phase disorder, study finds

Study highlights different roles of fat in powering and responding to exercise

Bielefeld University launches five new medical research projects

Endocrine Society’s new Scientific Statement offers guidance to spot hormonal causes of hypertension

Synthetic biologists engineer gut bacteria capable of sensing colitis

HIIT increases glucose metabolism and insulin sensitivity in diabetics, research reveals

Are we sleeping less than we used to?

Overall balance of bacteria on skin may be key factor for acne development

ULCA scientists discover how autoantibodies cause some cases of severe hypertriglyceridemia

BWH researchers develop ‘age-predicting clock’ for studying how to extend lifespan

Cellular markers of aging could reveal how insulin-producing cells begin to fail in type 2 diabetes

New initiative aims to study relationship between brain and obesity

Newly-discovered mechanism for compound may help prevent neurologic damage

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications