Metabolism News and Research

Latest Metabolism News and Research

New study discovers master switch that drives heart cell maturation process

A molecular switch that seems to be essential for embryonic heart cells to grow into more mature, adult-like heart cells has been discovered.

13 May 2015

Obese people at greater risk of developing cancer

Cancer is more likely to develop in people who are very overweight (obese), because surplus body fat interferes with various hormone cycles and with glucose and fat metabolism. On the occasion of European Obesity Day this coming Saturday (16 May), metabolic expert Alexandra Kautzky-Willer, Comprehensive Cancer Center at MedUni Vienna and Vienna General Hospital, draws attention to the fact that, even in Austria, more and more people are suffering from obesity.

12 May 2015

Brain protein plays key role in controlling binge drinking

Scientists at The Scripps Research Institute have discovered that a brain protein has a key role in controlling binge drinking in animal models. They found that deleting the gene for this protein in mice ramped up alcohol consumption and prevented the brain from signaling the rewarding properties of alcohol.

12 May 2015

β-amyloid deposition highly variable in synucleinopathy

A meta-analysis suggests large variability in the prevalence of β-amyloid deposition in patients with synucleinopathies.

8 May 2015

Removing bacterial biofilms could help prevent and treat colon cancers, study suggests

A team led by scientists at The Scripps Research Institute and Johns Hopkins University School of Medicine has uncovered a big clue to how bacteria may promote some colon cancers.

8 May 2015

Gene therapy is key to addressing Sanfilippo Syndrome, say Ohio scientists and clinicians

Gene therapy is the delivery of DNA into a patient's cells to replace faulty or missing genes—or adds new genes—in an attempt to cure cancer or make changes so the body is better able to fight off disease. Scientists and clinicians have identified a number of different ways to do this, in an effort to correct malfunctioning or mutated genes. Many gene therapy clinical trials are ongoing to assess the safety and potential benefits in patients with rare diseases.

8 May 2015

Researchers reveal mechanisms involved in development of metabolic complications linked to obesity

Metabolic complications of obesity and overweight, such as type 2 diabetes, are an important challenge to public health. Teams led by Nicolas Venteclef, Inserm Research Fellow (Cordeliers Research Centre, Inserm/Pierre and Marie Curie University Joint Research Unit 1138, Paris, France) and Irina Udalova (Kennedy Institute of Rheumatology, University of Oxford, UK) in collaboration with several teams, have succeeded in elucidating part of the mechanisms involved in the development of these metabolic complications associated with obesity.

8 May 2015

Phosphate Therapeutics reports positive results from PT20 trial in people with hyperphosphataemia

Phosphate Therapeutics Limited, a development-stage specialty pharmaceuticals company, today announces positive results from the PEACH pivotal study of PT20 in subjects with hyperphosphataemia related to dialysis dependent chronic kidney disease (DD-CKD).

7 May 2015

Certain metabolites in the blood could predict clinical outcome in children undergoing heart surgery

The study, published today in the journal Critical Care Medicine and carried out at Royal Brompton Hospital, followed children undergoing surgery for congenital heart disease, and found that by analysing metabolites in the blood -- molecules created as a result of metabolism -- it was possible to predict a child's clinical outcome.

6 May 2015

Scientists uncover new pharmaceutical strategy for treating melanoma

Scientists looking to better understand the mechanisms behind the origin and spread of melanoma tumors have uncovered a possible role for a decades-old antibacterial agent in treating these aggressive and increasingly common cancers.

6 May 2015

Relaxation response has significant impact on patients with gastrointestinal disorders

A pilot study has found that participating in a nine-week training program including elicitation of the relaxation response had a significant impact on clinical symptoms of the gastrointestinal disorders irritable bowel syndrome and inflammatory bowel disease and on the expression of genes related to inflammation and the body's response to stress.

6 May 2015

Metal oxide nanoparticles induce changes in human colon

Exposure of a model human colon to metal oxide nanoparticles, at levels that could be present in foods, consumer goods, or treated drinking water, led to multiple, measurable differences in the normal microbial community that inhabits the human gut.

5 May 2015

Novel method predicts risk of sudden cardiac death in hemodialysis patients

A new test has been developed to predict sudden cardiac death in hemodialysis patients in whom such forecasts were previously impossible. The novel method was presented at ICNC 12 by Dr Akiyoshi Hashimoto, a cardiologist at Sapporo Medical University in Japan. The test uses a combination of nuclear medicine, C-reactive protein and electrocardiogram (ECG).

5 May 2015

No evidence for cancer risk with growth hormone therapy

There is no evidence that growth hormone (GH) therapy increases the likelihood of neoplasms in children with no additional risk factors, says the Pediatric Endocrine Society Drug and Therapeutics Committee.

1 May 2015

Long-term histrelin implant shows promise for central precocious puberty

Long-term subcutaneous histrelin implant therapy is a viable option for patients with central precocious puberty who require continuous gonadotropin-releasing hormone analogue therapy, say researchers.

1 May 2015

Dr. Philipp Scherer to receive prestigious Banting Medal for Scientific Achievement from ADA

Dr. Philipp Scherer, Director of the Touchstone Center for Diabetes Research at UT Southwestern Medical Center, will receive the prestigious Banting Medal for Scientific Achievement, the highest honor bestowed by the American Diabetes Association.

30 Apr 2015

Adjustable gastric band surgery, weight management program offer similar benefits in diabetes patients

Weight loss is never easy, but it's important for overweight people with type 2 diabetes seeking to control their blood sugar levels and optimize their health. A small clinical trial among such patients led by Joslin Diabetes Center and Brigham and Women's Hospital researchers now has shown that two approaches--adjustable gastric band surgery and an intensive group-based medical diabetes and weight management program--achieved similar improvements in controlling blood sugar levels after one year.

29 Apr 2015

New genetic mutation appears to protect people from Type 2 diabetes

An international team of scientists led by a Cedars-Sinai researcher has identified a new genetic mutation that appears to protect people from developing Type 2 diabetes.

29 Apr 2015

Dramatic effects on colon cancer risk for Americans and Africans when diet swapped

Scientists have found dramatic effects on risk factors for colon cancer when American and African volunteers swapped diets for just two weeks.

28 Apr 2015

Simple device to treat sleep apnea may reduce diabetes risk

Using a simple device for eight hours a night to treat sleep apnea can help people with prediabetes improve their blood sugar levels and may reduce the risk of progressing to diabetes, according to a new study published online in the April 21, 2015, issue of the American Journal of Respiratory and Critical Care Medicine.

28 Apr 2015

Metabolism News and Research

Latest Metabolism News and Research

New study discovers master switch that drives heart cell maturation process

Obese people at greater risk of developing cancer

Brain protein plays key role in controlling binge drinking

β-amyloid deposition highly variable in synucleinopathy

Removing bacterial biofilms could help prevent and treat colon cancers, study suggests

Gene therapy is key to addressing Sanfilippo Syndrome, say Ohio scientists and clinicians

Researchers reveal mechanisms involved in development of metabolic complications linked to obesity

Phosphate Therapeutics reports positive results from PT20 trial in people with hyperphosphataemia

Certain metabolites in the blood could predict clinical outcome in children undergoing heart surgery

Scientists uncover new pharmaceutical strategy for treating melanoma

Relaxation response has significant impact on patients with gastrointestinal disorders

Metal oxide nanoparticles induce changes in human colon

Novel method predicts risk of sudden cardiac death in hemodialysis patients

No evidence for cancer risk with growth hormone therapy

Long-term histrelin implant shows promise for central precocious puberty

Dr. Philipp Scherer to receive prestigious Banting Medal for Scientific Achievement from ADA

Adjustable gastric band surgery, weight management program offer similar benefits in diabetes patients

New genetic mutation appears to protect people from Type 2 diabetes

Dramatic effects on colon cancer risk for Americans and Africans when diet swapped

Simple device to treat sleep apnea may reduce diabetes risk

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications