Metabolism News and Research

Latest Metabolism News and Research

Glucose-control drug sitagliptin does not raise risk of cardiovascular events

A clinical trial of the glucose-control drug sitagliptin among patients with type 2 diabetes and established cardiovascular disease has found it did not raise the risk of major adverse cardiovascular events.

9 Jun 2015

Lactobacillus reuteri may reduce risk of necrotizing enterocolitis in premature infants

A new study finds that supplementing enteral nutrition with Lactobacillus reuteri (L. reuteri) DSM 17938 as a probiotic may reduce the risk of necrotizing enterocolitis (NEC) in premature infants.

9 Jun 2015

Results from Intarcia's two phase 3 clinical trials of ITCA 650 to be presented at ADA's Scientific Session

Intarcia Therapeutics, Inc. today announced the presentation of results from its first two phase 3 clinical trials (FREEDOM-1 and FREEDOM-1 HBL) of its late-stage investigational candidate ITCA 650 (exenatide delivered continuously via a small matchstick-size subcutaneous osmotic mini-pump just once or twice yearly) at the 75th Scientific Sessions of the American Diabetes Association.

8 Jun 2015

People now have powerful new option for relieving dry mouth symptoms

People who suffer from dry mouth, or xerostomia, now have a powerful new option for relieving their symptoms. Building on the success of its antioxidant oral care product line, Dallas-based PerioSciences LLC is launching Dry Mouth AO ProGel and a new MILD formula of its Hydrating AO ProRinse. The new products, along with the established Hydrating AO ProRinse and AO ProToothpaste, provide a complete Hydrating Oral Care System.

8 Jun 2015

University at Albany researcher receives $1.76 million NIH grant to explore role of vitamin D in breast cancer

Each year, about 230,000 new cases of breast cancer are diagnosed in women in the U.S. It remains the third leading cause of death, behind only heart disease and lung cancer. Of the new cases, about 20 percent of women will be diagnosed with "triple negative" breast cancer (TNBC), a deadly form of breast cancer that does not respond to standard treatments such as tamoxifen or aromatase inhibitors.

7 Jun 2015

Medical experts call for accurate, standardized estrogen testing methods

Unreliable estrogen measurements have had a negative impact on the treatment of and research into many hormone-related cancers and chronic conditions. To improve patient care, a panel of medical experts has called for accurate, standardized estrogen testing methods in a statement published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

5 Jun 2015

Profil Institute for Clinical Research forms strategic partnership with Gubra

Profil Institute for Clinical Research, an clinical research organization (CRO) focused on diabetes, obesity and NAFLD/NASH, announced today a strategic collaboration with Gubra ApS, a metabolic preclinical and drug discovery company, to combine expertise and resources to discover and translate into clinical research novel drug targets, compounds and biomarkers addressing metabolic disease.

4 Jun 2015

Understanding link between polycystic ovary syndrome and diabetes

Nearly 50 percent of women with polycystic ovary syndrome (PCOS) develop pre-diabetes or type 2 diabetes before the age of 40, but the reasons for the correlation was unclear. In a new study in the American Journal of Physiology-Endocrinology and Metabolism, researchers report that inflammation is the cause for the increased diabetes risk in women with PCOS.

4 Jun 2015

Blood research could improve treatment for injured soldiers on the battlefield

Blood research conducted by biomedical engineers from The University of Texas at San Antonio College of Engineering, in collaboration with the Blood Research Program of the U.S. Army Institute of Surgical Research, could change the way injured soldiers are treated on the battlefield.

4 Jun 2015

UAB study finds how genetic variation in IIS/TOR molecular network may regulate variation in metabolism

New research from the University of Alabama at Birmingham finds genetic variants that occur in nature and lay the groundwork for future studies of diseases and treatments in humans.

3 Jun 2015

McMaster University researchers identify key protein required to maintain muscle strength during aging

What causes us to lose muscle strength as we age and how exercise can prevent it from happening has never been thoroughly understood, but McMaster University researchers have discovered a key protein required to maintain muscle mass and muscle strength during aging.

3 Jun 2015

National Psoriasis Foundation awards grants to support psoriatic disease research

The National Psoriasis Foundation awarded eight researchers each a one-year, $75,000 Discovery Grant to support the advancement of psoriatic disease research. By gaining a better understanding of the fundamentals of psoriatic disease--what causes psoriasis and psoriatic arthritis and what happens in the body when these diseases are present--scientists can work on better treatments and a cure.

3 Jun 2015

ASCO 2015: Berg presents data from BPM 31510 Phase Ib trial for solid tumors

Berg, a biopharmaceutical company committed to uncovering health solutions through a data-driven, biological approach, presented clinical research from its trials using its cancer drug BPM 31510 on Phase Ib solid tumors and preclinical data on triple negative breast cancer, at the 51st Annual Meeting of the American Society of Clinical Oncology (ASCO), May 29 – June 2 in Chicago.

2 Jun 2015

ERC Advanced Grants awarded to seven ETH researchers

Seven ETH Zurich professors have applied successfully for an ERC Advanced Grant, which is worth about CHF 2.5 million. Two of the seven received the coveted award for the second time.

1 Jun 2015

HarkerBIO, AMRI sign collaborative agreement to market structure-based drug discovery services

Albany Molecular Research Inc. (NASDAQ: AMRI) announced today that it has signed a collaborative agreement with biotechnology company HarkerBIO LLC to co-market their structure-based drug discovery services to global pharmaceutical and biotechnology clients.

1 Jun 2015

New article finds no compelling evidence for withdrawing nitrous oxide from operating theaters

A debate at this year's Euroanaesthesia meeting in Berlin will focus on whether laughing gas (nitrous oxide) should be banned from the operating room.

1 Jun 2015

Updated data from PROCLAIM national patient registry presented at 51st ASCO

Prometheus Laboratories, Inc. announced today the presentation of updated data from the PROCLAIM national patient registry in which first-line Proleukin® (aldesleukin for injection) therapy improved survival in patients with metastatic renal cell carcinoma (mRCC), compared to patients previously treated with targeted therapies.

1 Jun 2015

Researchers identify 763 proteins in human aqueous humor that nourish the cornea and the lens

Researchers conducting a comprehensive proteomics analysis of human aqueous humor samples identified 763 proteins - including 386 proteins detected for the first time - in this clear fluid that helps maintain pressure in the eye and nourishes the cornea and the lens.

30 May 2015

Novel biosensor chip measures pH, temperature, drugs and metabolism-related molecules

The future of medicine lies in ever greater precision, not only when it comes to diagnosis but also drug dosage. The blood work that medical staff rely on is generally a snapshot indicative of the moment the blood is drawn before it undergoes hours - or even days - of analysis.

30 May 2015

Patient characteristics may guide TKI use in CML

The likelihood of complications associated with tyrosine kinase inhibitor therapy in patients with chronic myeloid leukaemia may be reduced by considering patient factors and differences in the toxicity profiles of the different drug options, a review suggests.

29 May 2015

Metabolism News and Research

Latest Metabolism News and Research

Glucose-control drug sitagliptin does not raise risk of cardiovascular events

Lactobacillus reuteri may reduce risk of necrotizing enterocolitis in premature infants

Results from Intarcia's two phase 3 clinical trials of ITCA 650 to be presented at ADA's Scientific Session

People now have powerful new option for relieving dry mouth symptoms

University at Albany researcher receives $1.76 million NIH grant to explore role of vitamin D in breast cancer

Medical experts call for accurate, standardized estrogen testing methods

Profil Institute for Clinical Research forms strategic partnership with Gubra

Understanding link between polycystic ovary syndrome and diabetes

Blood research could improve treatment for injured soldiers on the battlefield

UAB study finds how genetic variation in IIS/TOR molecular network may regulate variation in metabolism

McMaster University researchers identify key protein required to maintain muscle strength during aging

National Psoriasis Foundation awards grants to support psoriatic disease research

ASCO 2015: Berg presents data from BPM 31510 Phase Ib trial for solid tumors

ERC Advanced Grants awarded to seven ETH researchers

HarkerBIO, AMRI sign collaborative agreement to market structure-based drug discovery services

New article finds no compelling evidence for withdrawing nitrous oxide from operating theaters

Updated data from PROCLAIM national patient registry presented at 51st ASCO

Researchers identify 763 proteins in human aqueous humor that nourish the cornea and the lens

Novel biosensor chip measures pH, temperature, drugs and metabolism-related molecules

Patient characteristics may guide TKI use in CML

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications