Metabolism News and Research

Latest Metabolism News and Research

Researchers find way to prevent noise-induced hearing loss

Researchers from Weill Cornell Medical College and the Gladstone Institutes have found a way to prevent noise-induced hearing loss in a mouse using a simple chemical compound that is a precursor to vitamin B3. This discovery has important implications not only for preventing hearing loss, but also potentially for treating some aging-related conditions that are linked to the same protein.

3 Dec 2014

New FDA data shows disparities still exist in medical research

The U.S. Food and Drug Administration (FDA) released data today on a dedicated website from six studies reflecting a two-month period in response to a requirement under the "FDA Action Plan to Enhance the Collection and Availability of Demographic Subgroup Data" to make transparent the percentage of female and minority participation in clinical trials for medications intended for all populations.

2 Dec 2014

Pain medicine specialist receives award for new advances in oral fluid testing

This year's Eastern Pain Society Scientific meeting was held at Mount Sinai Beth Israel Medical Center in New York City in late October and is one of the largest meetings of pain physicians and fellows in the tri-state area.

2 Dec 2014

Alport syndrome: an interview with Dr Paul Grint, CMO, Regulus

Alport Syndrome was first described by a physician called Cecil Alport, back in the late 1920s. It's a genetic disease that affects a certain type of collagen involved in the functioning of the kidney, the ear, and the eye.

1 Dec 2014

Exome sequencing refines 46,XY DSD diagnosis

Exome sequencing can identify a likely genetic cause of 46,XY disorders of sex development in about a third of cases, report researchers.

1 Dec 2014

Congenital hypothyroidism of central origin often requires treatment

Congenital hypothyroidism of central origin should not be dismissed as a mild condition and is worth screening for, say researchers.

1 Dec 2014

Inhibin B plus baseline LH levels aids hypogonadotropic hypogonadism diagnosis in boys

Researchers recommend measuring inhibin B concentration in combination with basal luteinising hormone as a first-line test to discover the underlying cause of delayed puberty in boys.

1 Dec 2014

Promising new therapeutic strategy for chronic kidney disease

Chronic kidney disease (CKD) affects at least one in four Americans who are older than 60 and can significantly shorten lifespan. Yet the few available drugs for CKD can only modestly delay the disease's progress towards kidney failure. Now, however, a team led by researchers at the Perelman School of Medicine at the University of Pennsylvania, has found an aspect of CKD's development that points to a promising new therapeutic strategy.

1 Dec 2014

PET/CT may improve differentiation of PTSD from MTBI

Hybrid imaging with positron emission tomography and computed tomography (PET/CT) in the pituitary region of the brain is a promising tool for differentiating military veterans with post-traumatic stress disorder (PTSD) from those with mild traumatic brain injury (MTBI), according to a new study presented at the annual meeting of the Radiological Society of North America (RSNA).

1 Dec 2014

New study explores how genes interact in relation to the behavior of muscles

How do the genes in the cells inside the body's muscles respond when the muscles are put to work? And how are these genes affected when muscles are not used? What importance do activity and, on the other hand, lack of activity have for the organism's metabolism, and thus also for diseases such as diabetes and obesity? These questions form the basis for a new study from the Department of Public Health at Aarhus University and the Institute of Sports Medicine at Bispebjerg Hospital.

28 Nov 2014

Functional connectivity loss may underlie Parkinson’s cognitive decline

Patients with Parkinson’s disease have deceases in functional connectivity over time and these correlate closely with cognitive decline, research shows.

27 Nov 2014

External artificial pancreas improves glucose control, reduces hypoglycemia risk

The world's first clinical trial comparing three alternative treatments for type 1 diabetes was conducted in Montréal by researchers at the IRCM and the University of Montreal, led by endocrinologist Dr. Rémi Rabasa-Lhoret.

27 Nov 2014

Researchers investigate role of mitochondria in expansion, survival of cancer stem cells

Cancer stem cells are particularly difficult to eradicate and are at the heart of why it is so hard to more effectively treat cancer patients, as the post-treatment survival of cancer stem cells drives tumour recurrence, the systemic spread of cancer and, ultimately, treatment failure.

From The University of Manchester 27 Nov 2014

Proper copper levels essential to health of the brain at rest, new study finds

In recent years it has been established that copper plays an essential role in the health of the human brain. Improper copper oxidation has been linked to several neurological disorders including Alzheimer's, Parkinson's, Menkes' and Wilson's.

27 Nov 2014

Researchers find unusual role of lactate in metabolism of alveolar soft part sarcoma

Researchers from Huntsman Cancer Institute at the University of Utah discovered the unusual role of lactate in the metabolism of alveolar soft part sarcoma (ASPS), a rare, aggressive cancer that primarily affects adolescents and young adults. The study also confirmed that a fusion gene is the cancer-causing agent in this disease.

27 Nov 2014

New microbial analysis has implications for protecting environment, energy recovery and human health

An international team of scientists from the Translational Genomics Research Institute and The Luxembourg Centre for Systems Biomedicine have completed a first-of-its-kind microbial analysis of a biological wastewater treatment plant that has broad implications for protecting the environment, energy recovery and human health.

27 Nov 2014

Presence of certain proteins in HDL can lead to cardiovascular risk

A current study by the MedUni Vienna has shown that changes to the "good cholesterol" HDL (High-Density Lipoprotein) can be associated with cardiovascular diseases: by developing a new laboratory test, scientists at the Institute of Medical Genetics and the Department of Nephrology & Dialysis (University Department of Internal Medicine III) at the MedUni Vienna have demonstrated for the first time that the presence of certain proteins in the HDL can lead to an increased risk of cardiovascular disease and mortality.

26 Nov 2014

Promethera Biosciences completes €25.33 million ($31.4 million) Series C fundraising

Promethera Biosciences, a Belgian biotechnology company developing Promethera HepaStem, a cell-based therapy for the treatment of in-born errors of metabolism and acquired liver diseases, today announces the completion of its Series C fundraising round. The company has raised €25.33 million ($31.4 million), including €20.33 million in capital.

26 Nov 2014

Researchers discover two common genetic variants associated with memory performance

In the largest study of the genetics of memory ever undertaken, an international researcher team including scientists from Boston University School of Medicine, have discovered two common genetic variants that are believed to be associated with memory performance.

25 Nov 2014

Scientists identify potential weakness in cancer's ability to become resistant to treatment

Scientists at the University of Manchester have discovered a potential weakness in cancer's ability to return or become resistant to treatment, by targeting the 'fuel' part of stem cells which allows tumours to grow.

25 Nov 2014

Metabolism News and Research

Latest Metabolism News and Research

Researchers find way to prevent noise-induced hearing loss

New FDA data shows disparities still exist in medical research

Pain medicine specialist receives award for new advances in oral fluid testing

Alport syndrome: an interview with Dr Paul Grint, CMO, Regulus

Exome sequencing refines 46,XY DSD diagnosis

Congenital hypothyroidism of central origin often requires treatment

Inhibin B plus baseline LH levels aids hypogonadotropic hypogonadism diagnosis in boys

Promising new therapeutic strategy for chronic kidney disease

PET/CT may improve differentiation of PTSD from MTBI

New study explores how genes interact in relation to the behavior of muscles

Functional connectivity loss may underlie Parkinson’s cognitive decline

External artificial pancreas improves glucose control, reduces hypoglycemia risk

Researchers investigate role of mitochondria in expansion, survival of cancer stem cells

Proper copper levels essential to health of the brain at rest, new study finds

Researchers find unusual role of lactate in metabolism of alveolar soft part sarcoma

New microbial analysis has implications for protecting environment, energy recovery and human health

Presence of certain proteins in HDL can lead to cardiovascular risk

Promethera Biosciences completes €25.33 million ($31.4 million) Series C fundraising

Researchers discover two common genetic variants associated with memory performance

Scientists identify potential weakness in cancer's ability to become resistant to treatment

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications