Metabolism News and Research

Latest Metabolism News and Research

TSRI study points way to potential therapies for hereditary spastic paraplegia

Scientists at The Scripps Research Institute have discovered that a gene mutation linked to hereditary spastic paraplegia, a disabling neurological disorder, interferes with the normal breakdown of triglyceride fat molecules in the brain. The TSRI researchers found large droplets of triglycerides within the neurons of mice modeling the disease.

30 Sep 2014

Research: Gut bacteria may cause animals to gain weight

A species of gut bacteria called Clostridium ramosum, coupled with a high-fat diet, may cause animals to gain weight. The work is published this week in mBio-, the online open-access journal of the American Society for Microbiology.

30 Sep 2014

Antibiotic exposure in infancy linked to childhood obesity

Repeated exposure to broad-spectrum antibiotics in the first two years of life is associated with early childhood obesity, say researchers from The Children's Hospital of Philadelphia in a retrospective study based on data from electronic health records from the extensive CHOP Care Network.

30 Sep 2014

Study provides support for new understanding of the immune system

A study published in the journal Science provides support for a new-and still controversial-understanding of the immune system. The research was conducted by collaborators in the U.S. and Europe, including Robert Cramer, PhD, an assistant professor of microbiology and immunology at the Geisel School of Medicine and member of the Dartmouth Lung Biology Center, and Kelly Shepherdson, PhD, at the time a graduate student in Cramer's lab.

29 Sep 2014

NeuroEM begins study to test Transcranial Electromagnetic Treatment in aged primates

NeuroEM Therapeutics, Inc., a Phoenix-based medical device R&D company, announced today that it has begun a study with a premiere research university to test its Transcranial Electromagnetic Treatment (TEMT) in aged primates.

25 Sep 2014

More reliable cardiorespiratory fitness data can be obtained using lean mass proportional measures

A recent study by the University of Eastern Finland shows that scaling maximal oxygen uptake and maximal workload by body weight confounds measures of cardiorespiratory fitness. It has been a common practice in exercise testing to scale the results by body weight and, according to researchers, this practice should be abandoned. More reliable data on cardiorespiratory fitness can be observed by using lean mass proportional measures.

25 Sep 2014

Pitt researchers awarded new $5.8 million NIH grant to develop microfluidic 3D liver model system

With a new $5.8 million, three-year award from the National Institutes of Health, researchers at the University of Pittsburgh School of Medicine will further develop a state-of-the-art, microfluidic 3D model system that mimics structure and function of the liver to better predict organ physiology, assess drug toxicity and build disease models.

25 Sep 2014

Absence of thyroid hormone during development can cause congenital deafness

Fatigue, weight gain, chills, hair loss, anxiety, excessive perspiration - these symptoms are a few of the signs that the thyroid gland, which regulates the body's heart rate and plays a crucial role in its metabolism, has gone haywire.

23 Sep 2014

Sequencing the Asian liver fluke genome: an interview with Dr Neil Young

Opisthorchis viverrini is a parasitic flatworm (or liver fluke) endemic throughout Thailand, the Lao People’s Democratic Republic, Vietnam and Cambodia. Humans are infected with this parasite when they eat a fluke encysted in inadequately cooked/preserved freshwater fish.

21 Sep 2014

Rosuvastatin promotes bone growth in mice with achondroplasia symptoms

Skeletal dysplasia is a group of rare diseases that afflict skeletal growth through abnormalities in bone and cartilage. Its onset hits at the fetal stage and is caused by genetic mutations.

18 Sep 2014

Researchers discover new molecular mechanism that plays crucial role in age-dependent diabetes

Ageing of insulin-secreting cells is coupled to a progressive decline in signal transduction and insulin release, according to a recent study by researchers at Karolinska Institutet in Sweden.

18 Sep 2014

Disrupting cancer regulator MYC: an interview with Professor Kim Janda

MYC is an oncogenic member of the basic helix-loop-helix-leucine zipper transcription factor family. In its monomeric form, MYC’s tertiary structure is intrinsically disordered and the protein is transcriptionally inactive.

17 Sep 2014

Zebrafish may hold key to unlocking a leading cause of respiratory diseases

A small freshwater fish found in many tropical aquariums may hold the key to unlocking one of the leading causes of respiratory diseases in humans.

17 Sep 2014

Dairy products contribute to overall metabolic health

Dairy is considered part of a healthy diet and dietary guidelines recommend the daily consumption of 2-4 portions of milk-based products such as milk, yogurt, cheese, cream and butter.

16 Sep 2014

Blocking bacteria's access to iron: an interview with Dr. Laxminarayana Devireddy

Iron is a key nutrient for nearly all living organisms, including bacteria. Iron is a cofactor for many enzymes necessary for basic metabolic reactions such as DNA synthesis and electron transport. Iron serves as the conduit for the electron transport chain that generates the energy necessary to drive the bacterial cell.

16 Sep 2014

Postmenopausal women with diverse gut bacteria exhibit more favorable ratio of estrogen metabolites

Postmenopausal women with diverse gut bacteria exhibit a more favorable ratio of estrogen metabolites, which is associated with reduced risk for breast cancer, compared to women with less microbial variation, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

12 Sep 2014

ChromaDex signs NIAGEN supply agreement with Healthy Directions

ChromaDex Corp., an innovative natural products company that provides proprietary ingredients and science-based solutions to the dietary supplement, food and beverage, cosmetic and pharmaceutical industries, announced today that it has entered into an ingredient supply agreement with Healthy Directions, a direct-to-consumer nutritional supplement retailer and wholly-owned subsidiary of Helen of Troy Limited.

11 Sep 2014

Clinical trial of stem cell-derived therapy for patients with Type 1 diabetes

Researchers at the University of California, San Diego School of Medicine, in partnership with ViaCyte, Inc., a San Diego-based biotechnology firm specializing in regenerative medicine, have launched the first-ever human Phase I/II clinical trial of a stem cell-derived therapy for patients with Type 1 diabetes.

11 Sep 2014

New project aims at delivering innovative test to improve safety of chemical products, drugs

The Genotrace project, combining targeted research and technology transfer, aims at delivering an innovative test to improve the safety of chemical products, drugs, human and animal food and the environment.

10 Sep 2014

Study shows importance of adding illness behavior in evaluation of patients with hormone disorders

Nicoletta Sonino and associates, in the current issue of the Journal of Clinical Endocrinology & Metabolism, point to the importance of including illness behavior (the ways in which people experience, perceive, evaluate and respond to their own health status) in the evaluation of patients with hormone disorders.

10 Sep 2014

Metabolism News and Research

Latest Metabolism News and Research

TSRI study points way to potential therapies for hereditary spastic paraplegia

Research: Gut bacteria may cause animals to gain weight

Antibiotic exposure in infancy linked to childhood obesity

Study provides support for new understanding of the immune system

NeuroEM begins study to test Transcranial Electromagnetic Treatment in aged primates

More reliable cardiorespiratory fitness data can be obtained using lean mass proportional measures

Pitt researchers awarded new $5.8 million NIH grant to develop microfluidic 3D liver model system

Absence of thyroid hormone during development can cause congenital deafness

Sequencing the Asian liver fluke genome: an interview with Dr Neil Young

Rosuvastatin promotes bone growth in mice with achondroplasia symptoms

Researchers discover new molecular mechanism that plays crucial role in age-dependent diabetes

Disrupting cancer regulator MYC: an interview with Professor Kim Janda

Zebrafish may hold key to unlocking a leading cause of respiratory diseases

Dairy products contribute to overall metabolic health

Blocking bacteria's access to iron: an interview with Dr. Laxminarayana Devireddy

Postmenopausal women with diverse gut bacteria exhibit more favorable ratio of estrogen metabolites

ChromaDex signs NIAGEN supply agreement with Healthy Directions

Clinical trial of stem cell-derived therapy for patients with Type 1 diabetes

New project aims at delivering innovative test to improve safety of chemical products, drugs

Study shows importance of adding illness behavior in evaluation of patients with hormone disorders

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology