Metabolism News and Research

Latest Metabolism News and Research

Agents targeting mitochondrial metabolism can have activity in leukemia

Results of a Phase I clinical trial showed that a new drug targeting mitochondrial function in human cancer cells was safe and showed some efficacy.

9 Sep 2014

Short-term use of DPP-4 inhibitors does not increase risk for pancreatic cancer

Researchers at the UNC Gillings School of Global Public Health and the UNC School of Medicine have found that a popular class of diabetes medications called DPP-4 inhibitors does not increase the short-term risk of pancreatic cancer, as was previously reported by other researchers.

5 Sep 2014

Positive clinical data for first procedural therapy to treat type 2 diabetes from Fractyl

Fractyl Laboratories Inc. today announced positive clinical data for the first procedural therapy to directly treat the underlying digestive causes of insulin resistance in patients with uncontrolled type 2 diabetes.

4 Sep 2014

Professor receives grant from NIH to test effects of high-intensity functional training

Katie Heinrich, assistant professor of kinesiology at Kansas State University, has been awarded an investigator-initiated grant from the National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases for more than $2.52 million.

4 Sep 2014

Treatment with SSRIs linked with increased failure risk of osseointegrated implants

The International and American Associations for Dental Research (IADR/AADR) have published a paper titled "SSRIs and the Risk of Osseointegrated Implant Failure - A Cohort Study.

4 Sep 2014

New regulatory component in infectious bacterium helps explain ability to survive in human body

The discovery of a new regulatory component in an infectious bacterium could aid efforts to explain its ability to survive in the human body, report microbiologists at The University of Texas Health Science Center at Houston (UTHealth) and University of Maryland, College Park, in the journal Science.

3 Sep 2014

Researchers examine role of blocking vagus nerve in weight loss

Among patients with morbid obesity, blocking the vagus nerve, which plays a role with appetite and metabolism, did not meet pre-specified efficacy objectives compared to a control group, although the intervention did result in greater weight loss, according to a study in the September 3 issue of JAMA.

3 Sep 2014

Researchers discover protein that may open door to new method of treating type 2 diabetes

The STK25 protein contributes to cell growth. Researchers at Sahlgrenska Academy have discovered that the protein also affects metabolism, demonstrating that elevated levels accelerate the progress of diabetes in mice.

3 Sep 2014

Coffee increases risk of prediabetes in young adults with hypertension

Coffee increases the risk of prediabetes in young adults with hypertension who are slow caffeine metabolisers, according to results from the HARVEST study presented at ESC Congress today by Dr Lucio Mos from Italy. People who drank more than three cups of coffee per day doubled their risk of prediabetes.

2 Sep 2014

Risk of obesity higher among adults who had been subjected to abuse as children

Being subjected to abuse during childhood entails a markedly increased risk of developing obesity as an adult.

2 Sep 2014

Researchers see benefit from behavioral weight loss program designed to curb food addiction

It may be possible to train the brain to prefer healthy low-calorie foods over unhealthy higher-calorie foods, according to new research by scientists at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University and at Massachusetts General Hospital.

2 Sep 2014

BIOCRATES launches first-ever bile acids kit based on targeted metabolite quantitation

Austrian BIOCRATES Life Sciences AG, internationally renowned developer and marketer of innovative targeted metabolomics solutions, further expands its range of metabolomics-based kits with the addition of its assay for the determination of endogenous bile acids, allowing a panel of up to 19 analytes to be simultaneously quantitated from a single 10 µL sample of human or mouse plasma.

1 Sep 2014

Bariatric surgery can provide valuable benefits to the brain

At bariatric facilities like Dr. Feiz and Associates, the life-changing benefits of bariatric surgery, including reduced risk of diabetes, cardiovascular disease and endocrine disorders are well established.

30 Aug 2014

Freiburg biochemists discover new mechanisms of brain disease

The failing in the work of nerve cells: An international team of researchers led by Prof. Dr. Chris Meisinger from the Institute of Biochemistry and Molecular Biology of the University of Freiburg has discovered how Alzheimer's disease damages mitochondria, the powerhouses of the cell.

29 Aug 2014

InnoPharma receives FDA approval for generic DACOGEN

InnoPharma, Inc. today announced the approval from the U.S. Food and Drug Administration for its Abbreviated New Drug Application (ANDA) for decitabine for injection, a generic version of Eisai Inc.'s DACOGEN.

29 Aug 2014

New method could help doctors better understand how drug abuse affects the brain

A new method for measuring and imaging how quickly blood flows in the brain could help doctors and researchers better understand how drug abuse affects the brain, which may aid in improving brain-cancer surgery and tissue engineering, and lead to better treatment options for recovering drug addicts.

29 Aug 2014

Amgen seeks FDA approval for evolocumab to treat patients with high cholesterol

Amgen today announced the submission of a Biologics License Application (BLA) to the U.S. Food and Drug Administration for evolocumab seeking approval for the treatment of high cholesterol.

28 Aug 2014

Armetheon raises $7 million in first round of financing

Armetheon, Inc., a biopharmaceutical company focused on developing novel mid- to late-stage cardiovascular drug candidates, today announced that it has raised $7.0 million in its first round of financing.

28 Aug 2014

Study: Many HIV infected African-Americans may not be receiving effective doses of maraviroc drug

Many African-Americans may not be getting effective doses of the HIV drug maraviroc, a new study from Johns Hopkins suggests. The initial dosing studies, completed before the drug was licensed in 2007, included mostly European-Americans, who generally lack a protein that is key to removing maraviroc from the body.

28 Aug 2014

Spanish scientists explore genetic basis of familial extreme longevity

In a recent report in Aging Cell, a multidisciplinary team of Spanish scientists, led by Tim Cash and Manuel Serrano at the Spanish National Cancer Research Centre, identify rare variants in the APOB gene in several families where exceptional longevity (>100 years of age) appears to cluster.

26 Aug 2014

Metabolism News and Research

Latest Metabolism News and Research

Agents targeting mitochondrial metabolism can have activity in leukemia

Short-term use of DPP-4 inhibitors does not increase risk for pancreatic cancer

Positive clinical data for first procedural therapy to treat type 2 diabetes from Fractyl

Professor receives grant from NIH to test effects of high-intensity functional training

Treatment with SSRIs linked with increased failure risk of osseointegrated implants

New regulatory component in infectious bacterium helps explain ability to survive in human body

Researchers examine role of blocking vagus nerve in weight loss

Researchers discover protein that may open door to new method of treating type 2 diabetes

Coffee increases risk of prediabetes in young adults with hypertension

Risk of obesity higher among adults who had been subjected to abuse as children

Researchers see benefit from behavioral weight loss program designed to curb food addiction

BIOCRATES launches first-ever bile acids kit based on targeted metabolite quantitation

Bariatric surgery can provide valuable benefits to the brain

Freiburg biochemists discover new mechanisms of brain disease

InnoPharma receives FDA approval for generic DACOGEN

New method could help doctors better understand how drug abuse affects the brain

Amgen seeks FDA approval for evolocumab to treat patients with high cholesterol

Armetheon raises $7 million in first round of financing

Study: Many HIV infected African-Americans may not be receiving effective doses of maraviroc drug

Spanish scientists explore genetic basis of familial extreme longevity

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology