Metabolism News and Research

Latest Metabolism News and Research

Mice exposed to fungicide tolyfluanid show metabolic changes

Mice exposed to the fungicide tolyfluanid (TF) showed metabolic changes similar to those that signify the development of the metabolic syndrome. The results, which were presented Sunday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

24 Jun 2014

Researchers develop GI microbiome modulators to treat prediabetes and diabetes

In adults with prediabetes, a new drug that alters microbial populations and their environment in the gastrointestinal (GI) tract improves glucose tolerance-the body's response to consuming carbohydrates- after four weeks of treatment and without a change in diet.

24 Jun 2014

Empagliflozin lowers blood pressure in patients with Type 2 diabetes and hypertension

An investigational drug to treat Type 2 diabetes, empagliflozin, lowers blood pressure in patients with Type 2 diabetes and hypertension (high blood pressure), a new study finds.

23 Jun 2014

Long-term mild cold exposure can stimulate brown fat growth

Long-term mild cold exposure can stimulate brown fat growth and activity in humans and may benefit glucose and energy metabolism, a new study finds.

23 Jun 2014

Researchers shown how free radicals contribute to fatty liver disease

An international team of scientists led by Monash University researchers has shown how free radicals contribute to type 2 diabetes, obesity and fatty liver disease.

23 Jun 2014

African American women respond differently to anti-inflammatory effect of aspirin than white women

African American women respond differently to the anti-inflammatory effect of aspirin than do white American women, new research finds.

23 Jun 2014

Experts from 96 countries gather in Chicago to attend ICE/ENDO 2014

ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and the Endocrine Society, has tallied more registrants than any other annual meeting in the Endocrine Society's nearly 100-year history.

23 Jun 2014

Empagliflozin drug reduces blood pressure in patients with Type 2 diabetes, hypertension

An investigational drug to treat Type 2 diabetes, empagliflozin, lowers blood pressure in patients with Type 2 diabetes and hypertension (high blood pressure), a new study finds. The results were presented Sunday in a late-breaking abstract at the joint meeting of the International Society of Endocrinology and The Endocrine Society: ICE/ENDO 2014 in Chicago.

23 Jun 2014

New research reveals gene's role in type 1 diabetes

New research describes details of how a diabetes-related gene functions on a biological pathway that affects the release of insulin. The study authors say that finding drugs that act on that pathway may eventually lead to a new treatment for type 1 diabetes.

20 Jun 2014

Susceptibility gene for type 1 diabetes regulates self-destruction of cell's energy factory

A team led by researchers from the Perelman School of Medicine at the University of Pennsylvania found that a susceptibility gene for type 1 diabetes regulates self-destruction of the cell's energy factory. They report their findings this week in Cell.

20 Jun 2014

New driver of atherosclerosis may prove to be promising therapeutic target

A new driver of atherosclerosis has been identified by researchers at UT Southwestern Medical Center. This molecule, known as 27HC (27-hydroxycholesterol), has been found to exacerbate the development of the condition, and may prove to be a promising therapeutic target.

20 Jun 2014

Healthy inflammation necessary to prevent metabolic diseases, study finds

Chronic tissue inflammation is typically associated with obesity and metabolic disease, but new research from UT-Southwestern Medical Center now finds that a level of "healthy" inflammation is necessary to prevent metabolic diseases, such as fatty liver.

19 Jun 2014

Common mutation in gene with overweight results in elevated ALAT values in children

A study carried out at the Institute of Biomedicine of the University of Eastern Finland shows that a common mutation in the PNPLA3 gene combined with overweight results in elevated ALAT values in children.

18 Jun 2014

Genetic variants linked to race that explains risk of death among patients taking Plavix after heart attack

Researchers have identified the first genetic variations linked to race that begin to explain a higher risk of death among some African American and Caucasian patients taking the anti-clotting drug clopidogrel (Plavix) after a heart attack.

18 Jun 2014

Researchers identify six gene loci associated with pulmonary diseases

In their investigations or so-called genome-wide association studies, the team of researchers compared the genetic profile of study participants to the forced vital capacity (FVC), a volume parameter of lung function.

18 Jun 2014

Researchers identify muscle-building mechanism that could be important in addressing sarcopenia

Sarcopenia - the significant loss of muscle mass and function that can occur as we age - is associated with many chronic conditions such as diabetes, high cholesterol and obesity.

18 Jun 2014

Scottsdale Healthcare, TGen initiate AG-120 clinical trial in patients with solid tumors

The Virginia G. Piper Cancer Center at Scottsdale Healthcare and the Translational Genomics Research Institute are studying the safety and effectiveness of a new drug, AG-120, for treatment of patients with solid tumors, especially those with brain tumors and gallbladder bile duct cancer.

18 Jun 2014

Single dose restores normal cellular signaling in mouse model of autism

In a further test of a novel theory that suggests autism is the consequence of abnormal cell communication, researchers at the University of California, San Diego School of Medicine report that an almost century-old drug approved for treating sleeping sickness also restores normal cellular signaling in a mouse model of autism, reversing symptoms of the neurological disorder in animals that were the human biological age equivalent of 30 years old.

18 Jun 2014

New hope for people suffering from depression

There is new hope for people suffering from depression. Researchers have identified a compound, hydroxynorketamine (HNK), that may treat symptoms of depression just as effectively and rapidly as ketamine, without the unwanted side effects associated with the psychoactive drug, according to a study in the July issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists- (ASA-).

17 Jun 2014

Fecal microbiota transplantation works by restoring healthy bacteria and functioning to recipient's gut

Fecal microbiota transplantation --- the process of delivering stool bacteria from a healthy donor to a patient suffering from intestinal infection with the bacterium Clostridium difficile --- works by restoring healthy bacteria and functioning to the recipient's gut, according to a study published this week in mBio-, the online open-access journal of the American Society for Microbiology.

17 Jun 2014

Metabolism News and Research

Latest Metabolism News and Research

Mice exposed to fungicide tolyfluanid show metabolic changes

Researchers develop GI microbiome modulators to treat prediabetes and diabetes

Empagliflozin lowers blood pressure in patients with Type 2 diabetes and hypertension

Long-term mild cold exposure can stimulate brown fat growth

Researchers shown how free radicals contribute to fatty liver disease

African American women respond differently to anti-inflammatory effect of aspirin than white women

Experts from 96 countries gather in Chicago to attend ICE/ENDO 2014

Empagliflozin drug reduces blood pressure in patients with Type 2 diabetes, hypertension

New research reveals gene's role in type 1 diabetes

Susceptibility gene for type 1 diabetes regulates self-destruction of cell's energy factory

New driver of atherosclerosis may prove to be promising therapeutic target

Healthy inflammation necessary to prevent metabolic diseases, study finds

Common mutation in gene with overweight results in elevated ALAT values in children

Genetic variants linked to race that explains risk of death among patients taking Plavix after heart attack

Researchers identify six gene loci associated with pulmonary diseases

Researchers identify muscle-building mechanism that could be important in addressing sarcopenia

Scottsdale Healthcare, TGen initiate AG-120 clinical trial in patients with solid tumors

Single dose restores normal cellular signaling in mouse model of autism

New hope for people suffering from depression

Fecal microbiota transplantation works by restoring healthy bacteria and functioning to recipient's gut

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