Metabolism News and Research

Latest Metabolism News and Research

Functional connectivity loss may underlie Parkinson’s cognitive decline

Patients with Parkinson’s disease have deceases in functional connectivity over time and these correlate closely with cognitive decline, research shows.

27 Nov 2014

External artificial pancreas improves glucose control, reduces hypoglycemia risk

The world's first clinical trial comparing three alternative treatments for type 1 diabetes was conducted in Montréal by researchers at the IRCM and the University of Montreal, led by endocrinologist Dr. Rémi Rabasa-Lhoret.

27 Nov 2014

Researchers investigate role of mitochondria in expansion, survival of cancer stem cells

Cancer stem cells are particularly difficult to eradicate and are at the heart of why it is so hard to more effectively treat cancer patients, as the post-treatment survival of cancer stem cells drives tumour recurrence, the systemic spread of cancer and, ultimately, treatment failure.

From The University of Manchester 27 Nov 2014

Proper copper levels essential to health of the brain at rest, new study finds

In recent years it has been established that copper plays an essential role in the health of the human brain. Improper copper oxidation has been linked to several neurological disorders including Alzheimer's, Parkinson's, Menkes' and Wilson's.

27 Nov 2014

Researchers find unusual role of lactate in metabolism of alveolar soft part sarcoma

Researchers from Huntsman Cancer Institute at the University of Utah discovered the unusual role of lactate in the metabolism of alveolar soft part sarcoma (ASPS), a rare, aggressive cancer that primarily affects adolescents and young adults. The study also confirmed that a fusion gene is the cancer-causing agent in this disease.

27 Nov 2014

New microbial analysis has implications for protecting environment, energy recovery and human health

An international team of scientists from the Translational Genomics Research Institute and The Luxembourg Centre for Systems Biomedicine have completed a first-of-its-kind microbial analysis of a biological wastewater treatment plant that has broad implications for protecting the environment, energy recovery and human health.

27 Nov 2014

Presence of certain proteins in HDL can lead to cardiovascular risk

A current study by the MedUni Vienna has shown that changes to the "good cholesterol" HDL (High-Density Lipoprotein) can be associated with cardiovascular diseases: by developing a new laboratory test, scientists at the Institute of Medical Genetics and the Department of Nephrology & Dialysis (University Department of Internal Medicine III) at the MedUni Vienna have demonstrated for the first time that the presence of certain proteins in the HDL can lead to an increased risk of cardiovascular disease and mortality.

26 Nov 2014

Promethera Biosciences completes €25.33 million ($31.4 million) Series C fundraising

Promethera Biosciences, a Belgian biotechnology company developing Promethera HepaStem, a cell-based therapy for the treatment of in-born errors of metabolism and acquired liver diseases, today announces the completion of its Series C fundraising round. The company has raised €25.33 million ($31.4 million), including €20.33 million in capital.

26 Nov 2014

Researchers discover two common genetic variants associated with memory performance

In the largest study of the genetics of memory ever undertaken, an international researcher team including scientists from Boston University School of Medicine, have discovered two common genetic variants that are believed to be associated with memory performance.

25 Nov 2014

Scientists identify potential weakness in cancer's ability to become resistant to treatment

Scientists at the University of Manchester have discovered a potential weakness in cancer's ability to return or become resistant to treatment, by targeting the 'fuel' part of stem cells which allows tumours to grow.

25 Nov 2014

Two researchers receive Naomi Berrie Award for Outstanding Research in Diabetes

Columbia University Medical Center has presented Andrew Hattersley, DM, and Mark McCarthy, MD, with the 16th Naomi Berrie Award for Outstanding Research in Diabetes, for their work on the genetics of the disease. Their research has contributed to the discovery of new forms of the disease, improvements in diagnostic methodology, and the development of more effective treatments.

25 Nov 2014

Two UH scientists named as fellows of AAAS

Two scientists from the University of Houston have been elected as fellows of the American Association for the Advancement of Science.

24 Nov 2014

Dantrolene drug may be effective treatment for rare form of diabetes

A commonly prescribed muscle relaxant may be an effective treatment for a rare but devastating form of diabetes, researchers at Washington University School of Medicine in St. Louis report.

24 Nov 2014

Researchers examine genomic landscapes of humans and mice

Looking across evolutionary time and the genomic landscapes of humans and mice, an international group of researchers has found powerful clues to why certain processes and systems in the mouse - such as the immune system, metabolism and stress response - are so different from those in people. Building on years of mouse and gene regulation studies, they have developed a resource that can help scientists better understand how similarities and differences between mice and humans are written in their genomes.

23 Nov 2014

Endocrine Society issues Clinical Practice Guideline on rare bone condition

The Endocrine Society today issued a Clinical Practice Guideline (CPG) for the diagnosis and treatment of Paget's disease of the bone, a condition where one or more bones in the body become oversized and weak.

23 Nov 2014

2014 Canadian Prix Galien for Innovative Product Award presented to Esbriet (pirfenidone)

This year's prestigious Canadian Prix Galien for Innovative Product Award has been presented to Esbriet (pirfenidone), a medicine used to treat idiopathic pulmonary fibrosis (IPF). It is the only medication approved in Canada with a specific IPF indication and is approved for mild to moderate IPF in adults.

21 Nov 2014

Changes in lipid layer of tear film may contribute to contact lens discomfort

Changes in the lipid layer of the eyes' natural tear film may contribute to the common problem of contact lens discomfort, reports a study in the December issue of Optometry and Vision Science, official journal of the American Academy of Optometry.

21 Nov 2014

Aequus Pharmaceuticals closes $4.2M private placement offering of special warrants

Aequus Pharmaceuticals Inc. (the "Company" or "Aequus") is pleased to announce that it has closed a brokered private placement offering (the "Brokered Offering") of special warrants for approximately C$3.7 million.

21 Nov 2014

Special receptor signalling mediates astrocytic hyperactivity in Alzheimer's disease mouse model

It has long been known that astrocytes change their shapes as a consequence of Alzheimer's. Cells located near the "plaques", as the protein deposits typical for this disease are called, grow in size and form additional extensions.

20 Nov 2014

Gene therapy transforms life for men with severe form of hemophilia B

Gene therapy developed at St. Jude Children's Research Hospital, University College London and the Royal Free Hospital has transformed life for men with a severe form of hemophilia B by providing a safe, reliable source of the blood clotting protein Factor IX that has allowed some to adopt a more active lifestyle, researchers reported.

19 Nov 2014

Metabolism News and Research

Latest Metabolism News and Research

Functional connectivity loss may underlie Parkinson’s cognitive decline

External artificial pancreas improves glucose control, reduces hypoglycemia risk

Researchers investigate role of mitochondria in expansion, survival of cancer stem cells

Proper copper levels essential to health of the brain at rest, new study finds

Researchers find unusual role of lactate in metabolism of alveolar soft part sarcoma

New microbial analysis has implications for protecting environment, energy recovery and human health

Presence of certain proteins in HDL can lead to cardiovascular risk

Promethera Biosciences completes €25.33 million ($31.4 million) Series C fundraising

Researchers discover two common genetic variants associated with memory performance

Scientists identify potential weakness in cancer's ability to become resistant to treatment

Two researchers receive Naomi Berrie Award for Outstanding Research in Diabetes

Two UH scientists named as fellows of AAAS

Dantrolene drug may be effective treatment for rare form of diabetes

Researchers examine genomic landscapes of humans and mice

Endocrine Society issues Clinical Practice Guideline on rare bone condition

2014 Canadian Prix Galien for Innovative Product Award presented to Esbriet (pirfenidone)

Changes in lipid layer of tear film may contribute to contact lens discomfort

Aequus Pharmaceuticals closes $4.2M private placement offering of special warrants

Special receptor signalling mediates astrocytic hyperactivity in Alzheimer's disease mouse model

Gene therapy transforms life for men with severe form of hemophilia B

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog