Metabolism News and Research

Latest Metabolism News and Research

TSRI scientists identify novel synthetic compound that reduces activity of a cancer-related protein

Scientists from the Florida campus of The Scripps Research Institute have identified a novel synthetic compound that sharply inhibits the activity of a protein that plays an important role in in the progression of breast and pancreatic cancers.

15 Jan 2015

Lung cancer rates are lower in higher-elevation counties, new study finds

Here's another potential reason to live up in the mountains. Lung cancer rates in both smokers and non-smokers are lower in higher-elevation counties in the western part of the United States, suggesting that oxygen may promote the incidence of lung cancer, according to a new study co-authored by a student at the Perelman School of Medicine at the University of Pennsylvania.

15 Jan 2015

Life satisfaction associated with higher bone density in older women

Women aged 60-70 who are satisfied with their lives have a higher bone density and they suffer from osteoporosis less frequently than their unsatisfied peers, according to a recent study completed at the University of Eastern Finland.

14 Jan 2015

Research findings may lead to new treatment for hypothyroidism

An international research team led by physician-scientists at Rush University Medical Center have gained new insights into hypothyroidism - a condition affecting about 10 million people in the U.S. - that may lead to new treatment protocols for the disease, particularly among the approximately 15 percent of patients for whom standard treatments are less effective.

14 Jan 2015

Atmospheric oxygen may play role in lung carcinogenesis, new study suggests

The ancient physician/alchemist, Paracelsus, said: "The dose makes the poison." According to a new study published in PeerJ, even oxygen may fall prey to the above adage. While essential to human life, aspects of oxygen metabolism may promote cancer. Capitalizing on the inverse relationship of oxygen concentration with elevation, researchers found lower rates of lung cancer at higher elevations, a trend that did not extend to non-respiratory cancers, suggesting that carcinogen exposure occurs via inhalation.

14 Jan 2015

Genetic finding could lead to new treatments for people living with blindness, vision loss

Finding genes for retinal degenerations has immediate benefits for people living with blindness and vision loss, their families, and their physicians. Establishing a genetic cause confirms the clinical diagnosis at the molecular level, helps predict the future visual prognosis, suggests therapies, and allows some patients to join clinical trials. While more than 200 genes for retinal degenerations have been identified, approximately 40-50% of cases remain a mystery.

13 Jan 2015

U-M researchers identify how amlexanox drug improves metabolism of sugar

Researchers at the University of Michigan have identified how a promising drug in clinical trials for the treatment of obesity and related metabolic disorders improves the metabolism of sugar by generating a new signal between fat cells and the liver.

13 Jan 2015

How quickly smokers metabolise nicotine may point to best quitting method

The success of different smoking cessation treatments could be predicted by how quickly smokers break down (metabolise) nicotine in their bodies, according to new research published in The Lancet Respiratory Medicine journal.

13 Jan 2015

New project explores role of gut microbiota in preventing diet- and brain-related diseases

A new project comprising thirty organisations from fifteen countries has started working together to study the microorganisms in our intestines and the role they play in health, well-being, and how they can help prevent diet- and brain-related diseases.

12 Jan 2015

Enzymes linked to diabetes, obesity play major roles in arthritis and leukemia

Enzymes linked to diabetes and obesity appear to play key roles in arthritis and leukemia, potentially opening up new avenues for treating these diverse diseases, according to new research at Washington University School of Medicine in St. Louis.

8 Jan 2015

Study: Synthetic triglyceride oil may provide hope for people with Huntington's disease

An early study suggests that a synthetic triglyceride oil called triheptanoin may provide hope for people with Huntington's disease. The study is published in the January 7, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Jan 2015

Research may provide new route to prevention and treatment of diabetes

An analysis of the genomes and epigenomes of lean and obese mice and humans has turned up a wealth of clues about how genes and the environment conspire to trigger diabetes, Johns Hopkins researchers say.

6 Jan 2015

New findings may lay groundwork of novel treatment for people with Huntington's disease

By adjusting the levels of a key signaling protein, researchers improved motor function and brain abnormalities in experimental animals with a form of Huntington's disease, a severe neurodegenerative disorder.

5 Jan 2015

Healthy Nordic diet reduces expression of inflammation-associated genes in adipose tissue

A Nordic study led by the Institute of Public Health and Clinical Nutrition at the University of Eastern Finland discovered that the health-promoting Nordic diet reduces the expression of inflammation-associated genes in subcutaneous adipose tissue. In overweight persons, the expression of these genes reduced without weight loss.

5 Jan 2015

New therapeutic approach shows potential for treating cancer

Case Western Reserve researchers have identified a two-pronged therapeutic approach that shows great potential for weakening and then defeating cancer cells.

31 Dec 2014

Janssen, Gilead to jointly develop darunavir-based, single-tablet regimen for HIV treatment

Janssen R&D Ireland announced today an amendment to its existing agreement with Gilead Sciences, Inc., initially established in 2011, for the development of a once daily, darunavir-based, single-tablet regimen (STR) for the treatment of people living with HIV.

29 Dec 2014

Eating habits and brain chemistry: an interview with Dr Kevin Hall

Several times every day, we choose when, where, what, with whom, and how much to eat. Many of these eating decisions have become automatic and don’t require cognitive effort.

22 Dec 2014

Continued exposure to high blood sugars may impact brain function in young diabetic children

Investigators have found that young children with type 1 diabetes (T1D) have slower brain growth compared to children without diabetes. A new study, published in the December issue of Diabetes, now available ahead of print, suggests that continued exposure to hyperglycemia, or high blood sugars, may be detrimental to the developing brain.

19 Dec 2014

UT Southwestern researchers find new potential target for halting tumor growth

UT Southwestern Medical Center researchers have discovered that brain tumors are capable of burning acetate for fuel, providing a new potential target for halting tumor growth.

19 Dec 2014

Findings show effective treatment for type 1 diabetes patients with severe hypoglycemia

Type 1 diabetes (T1D) patients who have developed low blood sugar (hypoglycemia) as a complication of insulin treatments over time are able to regain normal internal recognition of the condition after receiving pancreatic islet cell transplantation, according to a new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania, published online in Diabetes.

18 Dec 2014

Metabolism News and Research

Latest Metabolism News and Research

TSRI scientists identify novel synthetic compound that reduces activity of a cancer-related protein

Lung cancer rates are lower in higher-elevation counties, new study finds

Life satisfaction associated with higher bone density in older women

Research findings may lead to new treatment for hypothyroidism

Atmospheric oxygen may play role in lung carcinogenesis, new study suggests

Genetic finding could lead to new treatments for people living with blindness, vision loss

U-M researchers identify how amlexanox drug improves metabolism of sugar

How quickly smokers metabolise nicotine may point to best quitting method

New project explores role of gut microbiota in preventing diet- and brain-related diseases

Enzymes linked to diabetes, obesity play major roles in arthritis and leukemia

Study: Synthetic triglyceride oil may provide hope for people with Huntington's disease

Research may provide new route to prevention and treatment of diabetes

New findings may lay groundwork of novel treatment for people with Huntington's disease

Healthy Nordic diet reduces expression of inflammation-associated genes in adipose tissue

New therapeutic approach shows potential for treating cancer

Janssen, Gilead to jointly develop darunavir-based, single-tablet regimen for HIV treatment

Eating habits and brain chemistry: an interview with Dr Kevin Hall

Continued exposure to high blood sugars may impact brain function in young diabetic children

UT Southwestern researchers find new potential target for halting tumor growth

Findings show effective treatment for type 1 diabetes patients with severe hypoglycemia

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