Metabolism News and Research

Latest Metabolism News and Research

Researchers find decreased energy metabolism in heart cells as significant independent risk factor

Johns Hopkins researchers have identified a new way to predict which heart failure patients are likely to see their condition get worse and which ones have a better prognosis. Their study is one of the first to show that energy metabolism within the heart, measured using a noninvasive magnetic resonance imaging test, is a significant predictor of clinical outcomes, independent of a patient's symptoms or the strength of the heart's ability to pump blood, known as the ejection fraction.

11 Dec 2013

Father's diet before conception plays crucial role in health of offspring

Mothers get all the attention. But a study led by McGill researcher Sarah Kimmins suggests that the father's diet before conception may play an equally important role in the health of their offspring. It also raises concerns about the long-term effects of current Western diets and of food insecurity.

11 Dec 2013

New family of drugs may help combat childhood tumor

St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project study identifies drugs that enhance oxidative stress as possible weapon against most common pediatric soft tissue tumor

11 Dec 2013

Scientists study genetic, social and dietary factors influencing child obesity

Childhood obesity has more than doubled in the past 30 years. Now, an extensive and long-term research project aims at identifying the causes of this dramatic increase. In a study including 16.000 children from across Europe and spanning over several years, scientists are now trying to determine possible genetic and social factors influencing obesity in children.

11 Dec 2013

Drugs that enhance oxidative stress kill rhabdomyosarcoma tumor cells

Drugs that enhance a process called oxidative stress were found to kill rhabdomyosarcoma tumor cells growing in the laboratory and possibly bolstered the effectiveness of chemotherapy against this aggressive tumor of muscle and other soft tissue. The findings are the latest from the St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project and appear in the December 9 edition of the scientific journal Cancer Cell.

10 Dec 2013

NOXXON Pharma reports interim data from two phase IIa studies of anti-CXCL12/SDF-1 Spiegelmer NOX-A12

NOXXON Pharma disclosed interim data from two independent clinical phase IIa studies of the anti-CXCL12/SDF-1 Spiegelmer olaptesed pegol (NOX-A12) at the 55th annual meeting of the American Society of Hematology in New Orleans, LA, USA from 7-10 December 2013.

9 Dec 2013

Researchers uncover biological factor that may contribute to disparities in prostate cancer incidence

Researchers have uncovered a potential biological factor that may contribute to disparities in prostate cancer incidence and mortality between African-American and non-Hispanic white men in the United States, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.

9 Dec 2013

Scientists target protein-detection approach to systematically measure human repertoire of proteins

An international team of scientists led by Fred Hutchinson Cancer Research Center cancer proteomics expert Amanda Paulovich, M.D., has demonstrated the feasibility of large-scale, standardized protein measurements, which are necessary for validation of disease biomarkers and drug targets.

9 Dec 2013

Skin is capable of communicating with liver, say researchers

Researchers from the University of Southern Denmark have discovered that the skin is capable of communicating with the liver. The discovery has surprised the scientists, and they say that it may help our understanding of how skin diseases can affect the rest of the body.

9 Dec 2013

PKM2 protein controls mitosis, saving cancer cells from death and promoting brain tumor growth

Researchers have caught a protein they previously implicated in a variety of cancer-promoting roles performing a vital function in cell division, survival and development of brain tumors.

8 Dec 2013

Hummingbirds able to switch from burning glucose to fructose equally, say researchers

Hummingbird metabolism is a marvel of evolutionary engineering. These tiny birds can power all of their energetic hovering flight by burning the sugar contained in the floral nectar of their diet.

6 Dec 2013

ENC researchers point protein's role in prevention, management of type 2 diabetes

Nearly 26 million Americans have diabetes, costing an economically devastating $245 billion per year in medical costs. Projections suggest one in three Americans will have diabetes in 2050 if present trends continue.

6 Dec 2013

Study results show insulin sensitizers reduce risk of cancer in female patients with type 2 diabetes

A Cleveland Clinic-led study shows that a specific type of diabetes drug can decrease the risk of cancer in female patients with type 2 diabetes by up to 32 percent.

5 Dec 2013

Older people ingest too much magnesium, vitamin E in the form of dietary supplements

Many older people are ingesting too much magnesium and vitamin E in the form of dietary supplements. This was discovered by scientists of the Helmholtz Zentrum München in a population-based study; their results have been published in 'The Journal of Nutrition, Health and Aging'.

5 Dec 2013

Type 2 diabetes management: an interview with Professor Klaus Dugi, Corporate Senior Vice President Medicine, Boehringer Ingelheim

The rate of Type 2 Diabetes is rapidly increasing, particularly in Asian countries which make up more than 60 percent of the world’s diabetes population. So it’s really important physicians feel confident managing this chronic condition in their daily clinical practice.

5 Dec 2013

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

The first study of its kind, led by Melinda Sothern, PhD, CEP, Professor and Director of Behavioral and Community Health Sciences at LSU Health Sciences Center New Orleans School of Public Health, reveals that the same pro-inflammatory proteins linked to obesity and the metabolic syndrome in adults appear to protect children prior to puberty.

4 Dec 2013

BIDMC study shows carbon monoxide may have a role to play in treating cancer

In recent years, research has suggested that carbon monoxide, the highly toxic gas emitted from auto exhausts and faulty heating systems, can be used to treat certain inflammatory medical conditions. Now a study led by a research team at Beth Israel Deaconess Medical Center (BIDMC) shows for the first time that carbon monoxide may also have a role to play in treating cancer.

4 Dec 2013

Roche signs research collaboration and licensing agreement with Molecular Partners

Roche and Molecular Partners AG today announced that they have entered into a research collaboration and licensing agreement to discover, develop and commercialize several proprietary therapeutics incorporating Molecular Partners' DARPin biologics conjugated to toxic agents developed at Roche for the treatment of cancer.

4 Dec 2013

Researchers analyze protective effects of mild hypothermia on CNS injuries

There are few data on the effectiveness and mechanism underlying mild hypothermia in the treatment of central nervous system injuries. Therefore, there is a need to investigate the potentially beneficial effects of mild hypothermia on central nervous system injuries.

4 Dec 2013

Direct radiographic imaging reveals negative impact of adiposity in older men and women

Researchers at the National Institute for Aging are working to improve understanding about obesity and cancer. A study, published today in the journal Applied Physiology, Nutrition, and Metabolism, is the first to use direct radiographic imaging of adipose tissue rather than estimates like body mass index (BMI) or waist circumference, and focuses on the relationship between obesity and cancer risk in aging populations. Findings emphasize the negative impact of adiposity on long term health particularly for older men and women.

4 Dec 2013

Metabolism News and Research

Latest Metabolism News and Research

Researchers find decreased energy metabolism in heart cells as significant independent risk factor

Father's diet before conception plays crucial role in health of offspring

New family of drugs may help combat childhood tumor

Scientists study genetic, social and dietary factors influencing child obesity

Drugs that enhance oxidative stress kill rhabdomyosarcoma tumor cells

NOXXON Pharma reports interim data from two phase IIa studies of anti-CXCL12/SDF-1 Spiegelmer NOX-A12

Researchers uncover biological factor that may contribute to disparities in prostate cancer incidence

Scientists target protein-detection approach to systematically measure human repertoire of proteins

Skin is capable of communicating with liver, say researchers

PKM2 protein controls mitosis, saving cancer cells from death and promoting brain tumor growth

Hummingbirds able to switch from burning glucose to fructose equally, say researchers

ENC researchers point protein's role in prevention, management of type 2 diabetes

Study results show insulin sensitizers reduce risk of cancer in female patients with type 2 diabetes

Older people ingest too much magnesium, vitamin E in the form of dietary supplements

Type 2 diabetes management: an interview with Professor Klaus Dugi, Corporate Senior Vice President Medicine, Boehringer Ingelheim

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

BIDMC study shows carbon monoxide may have a role to play in treating cancer

Roche signs research collaboration and licensing agreement with Molecular Partners

Researchers analyze protective effects of mild hypothermia on CNS injuries

Direct radiographic imaging reveals negative impact of adiposity in older men and women

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