Metabolism News and Research

Latest Metabolism News and Research

Researchers discover how gene commonly linked to obesity contributes to weight gain

Researchers have discovered how a gene commonly linked to obesity—FTO—contributes to weight gain. The study shows that variations in FTO indirectly affect the function of the primary cilium, a little-understood hair-like appendage on brain and other cells.

23 May 2014

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

Researchers at the University of Maryland School of Medicine have identified a mutation in a fat-storage gene that appears to increase the risk for type 2 diabetes and other metabolic disorders, according to a study published online today in the New England Journal of Medicine.

23 May 2014

New discovery cracks code of metabolic pathway that allows certain cancerous tumors to thrive

In a breakthrough discovery at the Children's Medical Center Research Institute at UT Southwestern (CRI), a research team led by Ralph DeBerardinis, M.D., Ph.D., has taken a significant step in cracking the code of an atypical metabolic pathway that allows certain cancerous tumors to thrive, providing a possible roadmap for defeating such cancers.

23 May 2014

Pain receptors may hold key to treating obesity, diabetes and improving metabolic health

Blocking a pain receptor in mice not only extends their lifespan, it also gives them a more youthful metabolism, including an improved insulin response that allows them to deal better with high blood sugar.

23 May 2014

Agios Pharmaceuticals to present AG-221 Phase 1 study results at EHA meeting

Agios Pharmaceuticals, Inc., a leader in the fields of cancer metabolism and inborn errors of metabolism (IEMs), today announced that new clinical data from the Phase 1 study of AG-221, an orally available, selective, potent inhibitor of the mutated IDH2 protein, will be highlighted in an oral presentation at the 19th Congress of the European Hematology Association (EHA) taking place June 12 -15, 2014 in Milan, Italy.

22 May 2014

New technology needed to avoid improper placement of feeding tubes in pediatric patients

Universal guidelines and improvements in technology are needed to reduce injuries and deaths from improper placement of nasogastric feeding tubes in pediatric patients, according to a comprehensive review of published literature.

22 May 2014

Researchers identify existing drugs that could be "repurposed" to fight MERS-CoV

A team led by a University of Maryland School of Medicine (UM SOM) researcher, working as a grantee from the National Institutes of Health (NIH), has identified a number of existing drugs that could be "repurposed" to fight outbreaks of Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus (SARS-CoV).

22 May 2014

TSRI scientists receives $2M grant to study effects of early nutrition on lifespan and overall health

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded a $2 million grant from the National Institute on Aging of the National Institutes of Health to study the effects of early nutrition on lifespan and overall health.

22 May 2014

Supermodel mouse reveals critical role played by unknown gene that regulates metabolism

A lean "Supermodel" mouse type has revealed the potentially critical role played by a largely unknown gene that regulates metabolism, findings that could provide new insight into diseases ranging from diabetes to obesity, a new study by UT-Southwestern Medical Center researchers suggests.

21 May 2014

Physical activity may be able to prevent overweight women from developing heart disease

For otherwise healthy middle-aged women who are overweight or obese, physical activity may be their best option for avoiding heart disease, according to a study that followed nearly 900 women for seven years.

21 May 2014

Edison Pharmaceuticals' EPI-743 granted orphan designation for Leigh syndrome in Japan

Edison Pharmaceuticals has announced that the Japanese Ministry of Health, Labor and Welfare (MHLW) has granted Orphan Designation to EPI-743 for the treatment of Leigh syndrome.

21 May 2014

Space Station science: Microgravity on human thyroid carcinoma cells

The multi-national efforts that go into research aboard the International Space Station show that working together can yield results with universal benefits.

21 May 2014

Low physical activity, heavy use of electronic media linked to increased health risk in children

The Physical Activity and Nutrition in Children Study, PANIC, carried out by the Institute of Biomedicine at the University of Eastern Finland shows that low levels of physical activity combined with heavy use of electronic media and sedentary behaviour are linked to an increased risk for type 2 diabetes and vascular diseases already in 6-8 year-old children.

20 May 2014

Study: Premature babies' risk of brain injury influenced by genes

Premature babies' risk of brain injury is influenced by their genes, a new study suggests.

19 May 2014

Study finds association between sleep and obesity in young children

One of the most comprehensive studies of the potential link between reduced sleep and childhood obesity finds compelling evidence that children who consistently received less than the recommended hours of sleep during infancy and early childhood had increases in both obesity and in adiposity or overall body fat at age 7.

19 May 2014

Researchers examine how basic biology of aging drives chronic disease

A new collection of articles appearing in The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences examine how the basic biology of aging drives chronic disease.

16 May 2014

Isis Pharmaceuticals reports positive data from ISIS-GCGRRx Phase 2 study in patients with type 2 diabetes

Isis Pharmaceuticals, Inc. announced today positive data from a Phase 2 study of ISIS-GCGRRx in patients with type 2 diabetes uncontrolled on stable metformin therapy.

14 May 2014

Metabolon, GSK sign research collaboration agreement

Metabolon, Inc., a leading diagnostics and research services company offering metabolomics research platforms, has entered into a collaboration with GlaxoSmithKline to provide metabolomic profiling services and to collaborate on other research projects leveraging Metabolon's leading DiscoveryHD4 platform.

14 May 2014

Vitamin B12 shot does not boost energy, metabolism, says study

Feeling sluggish? Gaining weight? What you need is a shot in the arm, claim advertisers for trendy vitamin B12 injections.

14 May 2014

SGK1 enzyme, asthma and cancer therapies: an interview with Dr. Jonathan D. Powell, Johns Hopkins Kimmel Cancer Center

SGK1 stands for serum/glucocorticoid-regulated kinase 1. SGK1 is a member of the AGC kinase family, which is a huge family of kinases.

13 May 2014

Metabolism News and Research

Latest Metabolism News and Research

Researchers discover how gene commonly linked to obesity contributes to weight gain

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

New discovery cracks code of metabolic pathway that allows certain cancerous tumors to thrive

Pain receptors may hold key to treating obesity, diabetes and improving metabolic health

Agios Pharmaceuticals to present AG-221 Phase 1 study results at EHA meeting

New technology needed to avoid improper placement of feeding tubes in pediatric patients

Researchers identify existing drugs that could be "repurposed" to fight MERS-CoV

TSRI scientists receives $2M grant to study effects of early nutrition on lifespan and overall health

Supermodel mouse reveals critical role played by unknown gene that regulates metabolism

Physical activity may be able to prevent overweight women from developing heart disease

Edison Pharmaceuticals' EPI-743 granted orphan designation for Leigh syndrome in Japan

Space Station science: Microgravity on human thyroid carcinoma cells

Low physical activity, heavy use of electronic media linked to increased health risk in children

Study: Premature babies' risk of brain injury influenced by genes

Study finds association between sleep and obesity in young children

Researchers examine how basic biology of aging drives chronic disease

Isis Pharmaceuticals reports positive data from ISIS-GCGRRx Phase 2 study in patients with type 2 diabetes

Metabolon, GSK sign research collaboration agreement

Vitamin B12 shot does not boost energy, metabolism, says study

SGK1 enzyme, asthma and cancer therapies: an interview with Dr. Jonathan D. Powell, Johns Hopkins Kimmel Cancer Center

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