Metabolism News and Research

Latest Metabolism News and Research

Researchers identify new potential therapeutic target for lowering cholesterol

Researchers at the University of Michigan have identified a new potential therapeutic target for lowering cholesterol that could be an alternative or complementary therapy to statins.

12 Apr 2013

Protein EPAC2 plays major role in development of type 2 diabetes

A team of researchers at the Johns Hopkins Children's Center has found that a protein long believed to have a minor role in type 2 diabetes is, in fact, a central player in the development of the condition that affects nearly 26 million people in the United States alone and counts as one of the leading causes of heart disease, stroke and kidney, eye and nerve damage.

12 Apr 2013

Migraine severity and adiponectin: an interview with Dr. B. Lee Peterlin, Johns Hopkins University School of Medicine

Migraine affects an estimated 30 million people in the U.S, with the one year prevalence of migraine estimated at 12% of the general population, including 18% of all women and 6% of all men.

12 Apr 2013

Australian, Singapore researchers join hands to combat disease-causing bugs

The fight against a number of significant infectious diseases in the Asia-Pacific region has been given a boost through a new research collaboration between the National Health and Medical Research Council in Australia and the Agency for Science, Technology and Research in Singapore.

12 Apr 2013

Targeting pathway may lead to better hypertension treatments for at-risk patients

Obesity, heart disease, and high blood pressure (hypertension) are all related, but understanding the molecular pathways that underlie cause and effect is complicated.

12 Apr 2013

Weight loss surgery causes changes in DNA modifications

Gastric bypass surgery can drastically reduce the body weight of obese individuals in a short timeframe. For reasons that are not entirely clear, the surgery also leads to early remission of type 2 diabetes in the vast majority of patients.

12 Apr 2013

Discovery suggests new therapeutic target for treating dysfunctional beta cells, type 2 diabetes

Researchers at the University of California, San Diego School of Medicine have identified a previously unknown biological mechanism involved in the regulation of pancreatic islet beta cells, whose role is to produce and release insulin.

12 Apr 2013

Incidence of late-onset Alzheimer disease higher among African Americans

In a meta-analysis of data from nearly 6,000 African Americans, Alzheimer disease was significantly associated with a gene that have been weakly associated with Alzheimer disease in individuals of European ancestry, although additional studies are needed to determine risk estimates specific for African Americans, according to a study in the April 10 issue of JAMA, a Genomics theme issue.

11 Apr 2013

Research: African-Americans with ABCA7 gene variant have double risk of developing AD

African-Americans with a variant of the ABCA7 gene have almost double the risk of developing late-onset Alzheimer's disease compared with African-Americans who lack the variant.

10 Apr 2013

Tiny proteins prevent bacterial gene transcription

In the search for new antibiotics, researchers are taking an unusual approach: They are developing peptides, short chains of protein building blocks that effectively inhibit a key enzyme of bacterial metabolism.

10 Apr 2013

Researchers present data on ARQ 092 at 2013 AACR Annual Meeting

Researchers presented data today on ARQ 092, an AKT inhibitor in Phase 1 clinical development by ArQule, Inc. at the AACR Annual Meeting held in Washington, D.C., April 6-10, showing that this novel, oral agent inhibits the AKT pathway and has a manageable safety profile in an ongoing Phase 1 clinical trial.

10 Apr 2013

Mother's stress associated with development of pathologies related with obesity

The intrauterine environment plays an important role in the health of the offspring. Now, experts from the University of Navarra affirm that the mother's stress, due to socio-economic or psycho-social causes, is associated with the development of pathologies related with obesity.

10 Apr 2013

Relationship between obesity and PCOS may be exaggerated, say researchers

The relationship between obesity and polycystic ovary syndrome may be exaggerated, likely because the women who actively seek care for the condition tend to be heavier than those identified through screening of the general population, researchers report.

9 Apr 2013

Absorption Systems, Synerzys Lifecare partner to expand use of Biopharmaceutics Classification System

The preclinical contract research organization Absorption Systems, a global leader in pharmacokinetic testing of drugs, announces that it has entered into a partnership with the Indian pharmaceutical consulting firm Synerzys Lifecare Pvt Ltd.

9 Apr 2013

New national study examines marijuana use and prescription drug misuse

Individuals who use marijuana recreationally are more likely to misuse other drugs, including pain-controlling, but potentially addictive narcotics, sedatives and other prescription medications, than individuals who do not use marijuana, according to a new national study issued today by Quest Diagnostics, the world's leading provider of diagnostic information services.

From Quest Diagnostics 9 Apr 2013

Roche, Isis Pharmaceuticals to develop neurodegenerative therapeutics for Huntington's disease

Roche and Isis Pharmaceuticals, Inc today announced that they have formed an alliance to develop treatments for Huntington's disease based on Isis' antisense oligonucleotide technology.

9 Apr 2013

Research sheds new light on role of ATRX mutations in brain and pituitary

Research from Western University and Lawson Health Research Institute sheds new light on a gene called ATRX and its function in the brain and pituitary.

9 Apr 2013

Male smokers with low levels of serum bilirubin are at higher risk for lung cancer

Elevated levels of bilirubin in the blood get attention in the clinic because they often indicate that something has gone wrong with the liver. Now researchers have found that male smokers with low levels of the yellow-tinged chemical are at higher risk for lung cancer and dying from the disease.

8 Apr 2013

Carnitine compound in red meat and energy drinks increases risk for cardiovascular disease

A compound abundant in red meat and added as a supplement to popular energy drinks has been found to promote atherosclerosis - or the hardening or clogging of the arteries - according to Cleveland Clinic research published online this week in the journal Nature Medicine.

8 Apr 2013

Researchers study influence of muscle types, body metabolism in diabetes

Researchers in the Life Sciences Institute at the University of Michigan have challenged a long-held belief that whitening of skeletal muscle in diabetes is harmful.

8 Apr 2013

Metabolism News and Research

Latest Metabolism News and Research

Researchers identify new potential therapeutic target for lowering cholesterol

Protein EPAC2 plays major role in development of type 2 diabetes

Migraine severity and adiponectin: an interview with Dr. B. Lee Peterlin, Johns Hopkins University School of Medicine

Australian, Singapore researchers join hands to combat disease-causing bugs

Targeting pathway may lead to better hypertension treatments for at-risk patients

Weight loss surgery causes changes in DNA modifications

Discovery suggests new therapeutic target for treating dysfunctional beta cells, type 2 diabetes

Incidence of late-onset Alzheimer disease higher among African Americans

Research: African-Americans with ABCA7 gene variant have double risk of developing AD

Tiny proteins prevent bacterial gene transcription

Researchers present data on ARQ 092 at 2013 AACR Annual Meeting

Mother's stress associated with development of pathologies related with obesity

Relationship between obesity and PCOS may be exaggerated, say researchers

Absorption Systems, Synerzys Lifecare partner to expand use of Biopharmaceutics Classification System

New national study examines marijuana use and prescription drug misuse

Roche, Isis Pharmaceuticals to develop neurodegenerative therapeutics for Huntington's disease

Research sheds new light on role of ATRX mutations in brain and pituitary

Male smokers with low levels of serum bilirubin are at higher risk for lung cancer

Carnitine compound in red meat and energy drinks increases risk for cardiovascular disease

Researchers study influence of muscle types, body metabolism in diabetes

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology