Metabolism News and Research

Latest Metabolism News and Research

Genetically modified tomatoes mimic actions of good cholesterol

UCLA researchers have genetically engineered tomatoes to produce a peptide that mimics the actions of good cholesterol when consumed.

20 Mar 2013

Study provides new insights about polycystic ovarian syndrome, insulin resistance

A group of tiny RNA molecules with a big role in regulating gene expression also appear to have a role in causing insulin resistance in woman with polycystic ovary syndrome and, perhaps, in all women, researchers report.

20 Mar 2013

Study: Intake of carbohydrate-enriched foods after birth predisposes child to obesity later in life

Consumption of foods high in carbohydrates immediately after birth programs individuals for lifelong increased weight gain and obesity, a University at Buffalo animal study has found, even if caloric intake is restricted in adulthood for a period of time.

20 Mar 2013

Migraine severity may be predicted by blood levels of fat cell hormone

In a small, preliminary study of regular migraine sufferers, scientists have found that measuring a fat-derived protein called adiponectin (ADP) before and after migraine treatment can accurately reveal which headache victims felt pain relief.

18 Mar 2013

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that cancer is present, via diagnostics such as PET scans, and possibly offers an avenue for novel cancer therapies.

16 Mar 2013

Abiraterone's anti-androgenic properties may stop tumor growth of CRPC, says prize-winning Dutch study

As part of an EU-supported IMI-PREDECT consortium, a Dutch study showed that anti-androgenic properties of the drug abiraterone may provide an additional mechanism of action in blocking tumour growth of castration resistant prostate cancer (CRPC).

16 Mar 2013

Research: Decreased levels of vitamin D may influence smokers to develop tobacco-related cancer

New research appearing online today in Clinical Chemistry, the journal of AACC, shows that decreased levels of vitamin D may predispose smokers to developing tobacco-related cancer.

16 Mar 2013

Scientists develop pig brain model to study human brain development

A mutual curiosity about patterns of growth and development in pig brains has brought two University of Illinois research groups together. Animal scientists Rod Johnson and Ryan Dilger have developed a model of the pig brain that they plan to use to answer important questions about human brain development.

16 Mar 2013

Brown fat cells protective against obesity and diabetes

Brown fat is a hot topic, pardon the pun. Brown fats cells, as opposed to white fat cells, make heat for the body, and are thought to have evolved to help mammals cope with the cold. But, their role in generating warmth might also be applied to coping with obesity and diabetes.

15 Mar 2013

New research technique now available in Journal of Visualized Experiments

A new research technique, pioneered by Dr. Maria Angela Franceschini, will be published in JoVE (Journal of Visualized Experiments) on March 14th. Researchers at Massachusetts General Hospital and Harvard Medical School have developed a non-invasive optical measurement system to monitor neonatal brain activity via cerebral metabolism and blood flow.

15 Mar 2013

Results from GTx's Phase 2 clinical trial of enobosarm published online

GTx, Inc. today announced that the journal, The Lancet Oncology, has published online ahead of its April print edition the results from GTx's randomized, double-blind, placebo-controlled Phase 2 clinical trial of enobosarm to assess its effects on muscle wasting and physical function in patients with cancer.

15 Mar 2013

PCOS causes double jeopardy for those struggling hard to control glucose levels

Polycystic ovary syndrome, a condition affecting about 10 percent of women and characterized by excess male hormone and increased risk of diabetes and heart disease, appears to cause a sort of double jeopardy for those struggling the hardest to control blood sugar levels, researchers report.

14 Mar 2013

Iron imbalance caused by prion proteins leads to cell death in CJD, researchers find

An iron imbalance caused by prion proteins collecting in the brain is a likely cause of cell death in Creutzfeldt-Jakob disease (CJD), researchers at Case Western Reserve University School of Medicine have found.

14 Mar 2013

3-D structure of HNF-4α reveals new pockets that could be targeted with therapeutic drugs

Researchers at Sanford-Burnham Medical Research Institute have determined the complete three-dimensional structure of a protein called HNF-4α.

14 Mar 2013

Studies show protein semaphorin 3A helps detect acute kidney injury

A guidance cue that helps kidneys form may also be a red flag that they are in danger, researchers report.

13 Mar 2013

Bitter melon juice restricts ability of pancreatic cancer cells to metabolize glucose

A University of Colorado Cancer study published this week in the journal Carcinogenesis shows that bitter melon juice restricts the ability of pancreatic cancer cells to metabolize glucose, thus cutting the cells' energy source and eventually killing them.

13 Mar 2013

Lithera commences LIPO-202 Phase 2b trial for reduction of subcutaneous fat

Lithera, Inc., a clinical stage pharmaceutical company focused on lifestyle and medical indications in aesthetic medicine and ophthalmology, announced today that the first patient has been treated with LIPO-202 (Salmeterol Xinafoate for Injection) in its 500-patient Phase 2b "RESET" trial.

12 Mar 2013

Researchers uncover clear genetic link between fat and bone mass

When it comes to body shape, diet and exercise can only take us so far. Our body shape and geometry are largely determined by genetic factors. Genetics also have an impact on our body composition - including soft fat tissue and hard bone tissue - and can lead to excess fat or osteoporosis.

12 Mar 2013

Heavy drinkers have more rapid acetate uptake and metabolism: Study

In addition to its well-known effects on the CNS, alcohol consumption has a significant impact on metabolism. After consumption, the body rapidly begins converting ethanol to acetate, which can serve as an energy source for the brain and other organs.

11 Mar 2013

Researchers identify new mechanism in onset of motor neuron diseases

The British astrophysicist Stephen Hawking is likely to be the world's most famous person living with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. ALS is a progressive disease affecting motor neurons, nerve cells that control muscle function, and nearly always leads to death.

11 Mar 2013

Metabolism News and Research

Latest Metabolism News and Research

Genetically modified tomatoes mimic actions of good cholesterol

Study provides new insights about polycystic ovarian syndrome, insulin resistance

Study: Intake of carbohydrate-enriched foods after birth predisposes child to obesity later in life

Migraine severity may be predicted by blood levels of fat cell hormone

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Abiraterone's anti-androgenic properties may stop tumor growth of CRPC, says prize-winning Dutch study

Research: Decreased levels of vitamin D may influence smokers to develop tobacco-related cancer

Scientists develop pig brain model to study human brain development

Brown fat cells protective against obesity and diabetes

New research technique now available in Journal of Visualized Experiments

Results from GTx's Phase 2 clinical trial of enobosarm published online

PCOS causes double jeopardy for those struggling hard to control glucose levels

Iron imbalance caused by prion proteins leads to cell death in CJD, researchers find

3-D structure of HNF-4α reveals new pockets that could be targeted with therapeutic drugs

Studies show protein semaphorin 3A helps detect acute kidney injury

Bitter melon juice restricts ability of pancreatic cancer cells to metabolize glucose

Lithera commences LIPO-202 Phase 2b trial for reduction of subcutaneous fat

Researchers uncover clear genetic link between fat and bone mass

Heavy drinkers have more rapid acetate uptake and metabolism: Study

Researchers identify new mechanism in onset of motor neuron diseases

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology