Metabolism News and Research

Latest Metabolism News and Research

Old Order Amish children less likely to be overweight

Old Order Amish children are much more physically active and three times less likely to be overweight than non-Amish children, which may provide them with some long-term protection against developing Type 2 diabetes, University of Maryland School of Medicine researchers report in the journal Diabetes Care.

24 Oct 2012

Metabolic pathway for insulin effects of sleep identified

Sleep deprivation reduces insulin sensitivity in human fat cells, which could, over time, lead to metabolic disorders such as diabetes, researchers report.

23 Oct 2012

Rhythm presents RM-131 Phase 1 clinical trial results for diabetic gastroparesis at ACG 2012

Rhythm announced today the results of two Phase 1 clinical trials of RM-131, the company's novel ghrelin agonist for the treatment of diabetic gastroparesis, which demonstrated that RM-131 greatly accelerates gastric emptying in healthy subjects with good tolerability.

22 Oct 2012

Studies explore mechanisms linked to self-control

Converging scientific evidence - not to mention a great deal of life experience - tells us that self-control is an important ability. It helps us keep our cool, get things done, and resist the things that tempt us. Scientists believe that gaining a clearer understanding of how self-control works could provide critical insights into addressing some of the large-scale problems facing society today, including obesity and addiction.

20 Oct 2012

$Researchers find new way to assess risk of osteoporosis, bone fractures in women$

Researchers find new way to assess risk of osteoporosis, bone fractures in women

For women of mixed racial or ethnic backgrounds, a new method for measuring bone health may improve the odds of correctly diagnosing their risk of osteoporosis and bone fractures, according to a UCLA-led study.

20 Oct 2012

Lipid droplets play an unexpected role in embryo development

Histones are proteins needed to assemble DNA molecules into chromosomes. They have long represented a classic balancing act in biology; too few histone molecules result in DNA damage, while too many histones are toxic to the cell. New research at the University of Rochester is causing a fundamental shift in the concept of histone balance and the mechanism behind it.

19 Oct 2012

Losing weight does not lead to improved fertility in women

Losing weight does not lead to improved fertility in women, but does improve sexual function, according to Penn State College of Medicine researchers.

19 Oct 2012

Study sheds light on how overeating can lead to obesity and diabetes

New research from Mount Sinai School of Medicine sheds light on how overeating can cause a malfunction in brain insulin signaling, and lead to obesity and diabetes. Christoph Buettner, MD, PhD, Associate Professor of Medicine (Endocrinology, Diabetes and Bone Disease) and his research team found that overeating impairs the ability of brain insulin to suppress the breakdown of fat in adipose tissue.

19 Oct 2012

Neuralstem initiates second cohort NSI-189 Phase Ib trial in major depressive disorder

Neuralstem, Inc. announced that it has begun dosing the second cohort of patients in its ongoing Phase Ib to test the safety of NSI-189 in the treatment of major depressive disorder (MDD).

19 Oct 2012

New research sheds light on consequence of overeating

New research from Mount Sinai School of Medicine sheds light on how overeating can cause a malfunction in brain insulin signaling, and lead to obesity and diabetes.

18 Oct 2012

Nonpsychiatric medical costs high in bipolar disorder patients

The use of nonpsychiatric healthcare services is greater and associated costs higher in bipolar disorder patients than in those without the mood disorder, results from a Taiwanese study show.

17 Oct 2012

High-carb diet may increase risk of mild cognitive impairment among older people

People 70 and older who eat food high in carbohydrates have nearly four times the risk of developing mild cognitive impairment, and the danger also rises with a diet heavy in sugar, Mayo Clinic researchers have found.

17 Oct 2012

Study finds low testosterone levels among obese teen boys

A study by the University at Buffalo shows for the first time that obese males ages 14 to 20 have up to 50 percent less total testosterone than do normal males of the same age, significantly increasing their potential to be impotent and infertile as adults.

17 Oct 2012

Researchers identify critical mechanisms of epigenetic cell programming

A team of researchers at the IRCM, supervised by Dr. Jacques Drouin, reprogrammed the identity of cells in the pituitary gland and identified critical mechanisms of epigenetic cell programming.

17 Oct 2012

Resverlogix commences RVX-208 Phase 2 trial in pre-diabetes mellitus

Resverlogix Corp. today announced that it has initiated an exploratory Phase 2 clinical trial in patients with pre-diabetes mellitus to examine the effects of RVX-208 and ApoA-I production on glucose metabolism.

17 Oct 2012

Mephedrone and memory loss: an interview with Craig Motbey

Mephedrone is a fairly new designer drug which has been around for a few years. It exploded in popularity in Europe (and particularly in the UK) before it started to spread in a major way elsewhere.

16 Oct 2012

Fat cells need sleep to function properly: Study

In a study that challenges the long-held notion that the primary function of sleep is to give rest to the brain, researchers have found that not getting enough shut-eye has a harmful impact on fat cells, reducing by 30 percent their ability to respond to insulin, a hormone that regulates energy.

16 Oct 2012

FOS prebiotic could replace intravenous feeding in pediatric patients with intestinal failure

Adding the right prebiotic to the diets of pediatric patients with intestinal failure could replace intravenous feeding, says a new University of Illinois study.

16 Oct 2012

Exercise and healthy eating reduce body fat and preserve muscle in adults

Exercise and healthy eating reduce body fat and preserve muscle in adults better than diet alone, according to a study funded and conducted by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health.

16 Oct 2012

AAPS recognizes top scientists in pharmaceutical sciences

During the Opening Session of the 2012 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, AAPS President David Y. Mitchell, Ph.D., presented the following ground-breaking researchers with awards commemorating their contributions to the pharmaceutical sciences:

15 Oct 2012