Metabolism News and Research

Latest Metabolism News and Research

Disrupting mTORC1 protein complex extends lifespan

One of the secrets to a longer, healthier life is simply to eat less. When subjected to calorie restriction (CR), typically defined as a 20-40% reduction in caloric intake with corresponding maintenance of proper nutrition, animals in labs not only live longer, but also have improved insulin sensitivity and glucose tolerance, both of which decline during aging.

30 Mar 2012

Birth weight may identify future metabolic risks in girls

Heavier female babies are more likely to develop diabetes and related metabolic risks when they grow up compared with their male counterparts, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism.

30 Mar 2012

Vitamin D-fortified doogh improves inflammatory markers in type 2 diabetics

Daily intake of vitamin D-fortified doogh (Persian yogurt drink) improved inflammatory markers in type 2 diabetics and extra calcium conferred additional anti-inflammatory benefits, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism.

30 Mar 2012

New synthetic small molecules could treat obesity, diabetes and sleep disorders

Scientists from the Florida campus of The Scripps Research Institute have synthesized a pair of small molecules that dramatically alter the core biological clock in animal models, highlighting the compounds' potential effectiveness in treating a remarkable range of disorders-including obesity, diabetes, high cholesterol, and serious sleep disorders.

30 Mar 2012

Research supports link between alcohol consumption and type II diabetes

Subjects in a cohort in Sweden, some of whom had been exposed to a community intervention program to prevent diabetes, were evaluated 8-10 years after baseline for the presence of diabetes mellitus or impaired glucose metabolism in relation to a baseline report of alcohol consumption.

30 Mar 2012

Researchers discover MicroRNAs as new switch of adipose cell development

Hunger has always threatened mankind. This makes it unsurprising that human bodies attempt to store all surplus nourishment in adipose tissue. In developed countries, this life-saving craving is turning into a problem and obesity—adiposity—is turning into a danger. Why, though, does excess fat the body ill? How does fat trigger diabetes? And can these superfluous fat reserves be turned into warmth and just as well burnt?

30 Mar 2012

Thyroidectomy may increase risk of postoperative complications in the elderly

Elderly patients who undergo thyroid surgery are at a much higher risk than their younger counterparts for serious cardiac, pulmonary and infectious complications, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

30 Mar 2012

Study explains how rapamycin also causes insulin resistance

A Penn- and MIT-led team explained how rapamycin, a drug that extends mouse lifespan, also causes insulin resistance. The researchers showed in an animal model that they could, in principle, separate the effects, which depend on inhibiting two protein complexes, mTORC1 and mTORC2, respectively.

30 Mar 2012

Roche announces increase in offer price for outstanding Illumina shares

Roche announced today that it has increased its offer price for all outstanding publicly-held shares of Illumina, Inc. to US$ 51.00 per share in cash.

From Illumina, Inc. 29 Mar 2012

Researchers describe unexpected role of p75NTR in type 2 diabetes

Scientists at the Gladstone Institutes have discovered a key protein that regulates insulin resistance-the diminished ability of cells to respond to the action of insulin and which sets the stage for the development of the most common form of diabetes. This breakthrough points to a new way to potentially treat or forestall type 2 diabetes, a rapidly growing global health problem.

29 Mar 2012

Gene therapy improves chylomicron metabolism in LPLD patients

Amsterdam Molecular Therapeutics, a leader in the field of human gene therapy, announced today data demonstrating that one-time administration of the gene therapy Glybera (alipogene tiparvovec) is able to markedly improve chylomicron (fat particles in the blood) metabolism following consumption of a low fat meal.

29 Mar 2012

Meditation decreases depression, anxiety and stress in school teachers

Schoolteachers who underwent a short but intensive program of meditation were less depressed, anxious or stressed - and more compassionate and aware of others' feelings, according to a UCSF-led study that blended ancient meditation practices with the most current scientific methods for regulating emotions.

29 Mar 2012

EU's Safety Evaluation Ultimately Replacing Animal Testing initiative tests Roche's xCELLigence system

Roche's xCELLigence RTCA System is being used in the European Union's SEURAT (Safety Evaluation Ultimately Replacing Animal Testing) initiative to run five years from 2011 to 2016.

From Roche Sequencing and Life Science 29 Mar 2012

Interleukin, U-M School of Dentistry complete enrollment in PST Genetic Test study

The University of Michigan School of Dentistry and Interleukin Genetics, Inc. announced today the completion of patient enrollment for a landmark clinical study using Interleukin's PST Genetic Test to determine if dental patients can be risk-stratified to guide frequency of preventive dental visits and reduce the adverse outcomes of periodontal disease progression, such as tooth loss.

29 Mar 2012

Inhibitory control test and lactulose for MHE saves more than $3 million over 5 years

A late stage liver condition, known as minimal hepatic encephalopathy (MHE), is associated with impaired driving skills and greater risk of motor vehicle accidents. Cost analysis of management strategies for detection and treatment of MHE are published in the April issue of Hepatology, a journal of the American Association for the Study of Liver Diseases.

29 Mar 2012

Understanding quantum metabolism may help stop cancer growth

The theory of quantum metabolism is the idea that quantum processes, such as entanglement, influence the metabolism of cells. This idea offers scientists a new explanation for the metabolic changes that cause healthy cells to transform into cancerous ones. The metamorphosis gives cancerous cells the ability to outcompete healthy cells for space and nutrients, causing the disease to spread.

28 Mar 2012

Hyperinsulinemia itself not a cause of atherosclerosis

A number of studies have shown that excess insulin circulating in the bloodstream is a major independent risk factor for cardiovascular disease. However, a new study from Joslin Diabetes Center finds that this condition, called hyperinsulinemia, is itself not a cause of atherosclerosis.

28 Mar 2012

CSEP develops two guidelines to improve health and activity levels of infants, toddlers

In response to an urgent call from public health, health care, child care, and fitness practitioners, the Canadian Society for Exercise Physiology (CSEP), with assistance from multiple partners, has developed two important sets of guidelines directed at improving the health and activity levels of infants and toddlers.

28 Mar 2012

New pre-clinical data on Rexahn's RX-3117 study to be presented at AACR meeting

Rexahn Pharmaceuticals, Inc., a clinical stage pharmaceutical company commercializing potential best in class oncology and CNS therapeutics, today announced that it will present new pre-clinical data on its oncology compound RX-3117 during a poster session at the American Association for Cancer Research (AACR) 103rd Annual Meeting being held in Chicago, Illinois, March 31 - April 4, 2012, at the McCormick Place Convention Center.

28 Mar 2012

UT Southwestern researcher wins prestigious award from International Atherosclerosis Society

Dr. Helen Hobbs, a preeminent researcher on the genetics of cholesterol metabolism at UT Southwestern Medical Center, has won a prestigious award from the International Atherosclerosis Society.

28 Mar 2012