Metabolism News and Research

Latest Metabolism News and Research

Working of master regulator protein phosphatase 1

Protein phosphorylation is a process by which proteins are flipped from one activation state to another. It is a crucial function for most living beings, since phosphorylation controls nearly every cellular process, including metabolism, gene transcription, cell-cycle progression, cytoskeletal rearrangement and cell movement.

26 Mar 2010

Sirolimus-based immunosuppression improves survivals after transplantation for HCC

A recent study found that sirolimus-based immunosuppression following liver transplantation in patients with non-resectable hepatocellular carcinoma (liver cancer) significantly increases survival rates for this patient population.

26 Mar 2010

Changing drug therapy can help breast cancer patients get full benefit of tamoxifen treatment

26 Mar 2010

Standard HCV therapy less effective in urban minority patients: Study

A recent study confirms that the standard hepatitis C therapy, pegylated interferon and ribavirin, is significantly less effective in urban minority patients treated in an ordinary clinical practice setting compared with results produced during clinical trials.

26 Mar 2010

AVASTIN receives Health Canada approval for patients with GBM

Roche Canada announced today that Health Canada has approved AVASTIN(R) (bevacizumab), as a single agent, for the treatment of patients with glioblastoma multiforme, the most aggressive primary malignant brain tumour, after relapse or disease progression, following prior therapy.

26 Mar 2010

Findings suggest adipose inflammation is necessary for fat cell turnover

It has been a common opinion that inflammation in adipose tissue may cause insulin resistance, and thereby type 2 diabetes. However, recent research from the Swedish medical university Karolinska Institutet, published in the New England Journal of Medicine, question the theory that inflammation in the body fat is only pernicious.

25 Mar 2010

Changing drug therapy can help breast cancer patients get full benefit of Tamoxifen

Recently published research has shown that some breast cancer patients taking tamoxifen may not be getting the full benefit of their treatment because they have also been taking selective serotonin reuptake inhibitors (SSRIs), prescribed drugs that inhibit the effect of an important enzyme. Now researchers have developed a strategy for overcoming this problem, the seventh European Breast Cancer Conference (EBCC7) in Barcelona will hear today (Wednesday).

25 Mar 2010

Bariatric surgery may delay onset of type 2 diabetes, says study

A team of researchers, led by a UC Davis veterinary endocrinologist, has shown for the first time that a surgical procedure in rats that is similar to bariatric surgery in humans can delay the onset of type 2 diabetes.

25 Mar 2010

Breathing diesel exhaust during pregnancy linked with sluggishness in offspring

Breathing diesel exhaust during pregnancy is associated with sluggishness in offspring. Researchers writing in BioMed Central's open access journal Particle and Fibre Toxicology studied the effects of pollution exposure in mice, finding that the offspring of mothers who breathed diesel fumes while pregnant were less likely to show spontaneous movement.

23 Mar 2010

CTSI licenses GeneGo's pathway analysis suite and database searching tool

GeneGo, Inc., a leading provider of software and databases for systems biology, today announced that the Indiana Clinical and Translational Sciences Institute has licensed its pathway analysis suite MetaCore and its database searching tool Eureka.

23 Mar 2010

Researchers investigate link between consumption of high-fructose corn syrup and obesity

A Princeton University research team has demonstrated that all sweeteners are not equal when it comes to weight gain: Rats with access to high-fructose corn syrup gained significantly more weight than those with access to table sugar, even when their overall caloric intake was the same.

23 Mar 2010

Novo Nordisk Foundation donates $160M to University of Copenhagen for metabolic research

The Center will conduct research into Type 2 diabetes, among other diseases, and will acquire the capacities and resources to establish itself as one of the leading international research centers in the world. With 885 million Danish kroner (approx. 160 million US Dollars) from the Novo Nordisk Foundation, a team of 5 leading research scientists will be headhunted by the University to oversee "The Novo Nordisk Foundation Center for Basic Metabolic Research".

From Novo Nordisk 23 Mar 2010

Walnuts affect genes related to prostate tumor growth: Study

Walnut consumption slows the growth of prostate cancer in mice and has beneficial effects on multiple genes related to the control of tumor growth and metabolism, UC Davis and the U.S. Department of Agriculture Western Regional Research Center in Albany, Calif. have found.

23 Mar 2010

Legacy Biotechnologies, Phillips Sales and Marketing reach agreement to distribute Reme-Flu remedy

Nuvilex, Inc., announces today that Legacy Biotechnologies, Inc., its joint venture partner in Reme-Flu™ homeopathic flu remedy, has reached an agreement with Phillips Sales and Marketing to begin the national sales and marketing campaign for retail distribution of Reme-Flu™.

22 Mar 2010

High dose of Zocor could lead to muscle injury, warns FDA

The U.S. Food and Drug Administration today warned patients and healthcare providers about the potential for increased risk of muscle injury from the cholesterol-lowering medication Zocor (simvastatin) 80 mg.

20 Mar 2010

A.P. Pharma's NDA for APF530 in prevention of CINV: FDA issues Complete Response Letter

A.P. Pharma, Inc., a specialty pharmaceutical company, today announced that it received a Complete Response Letter from the U.S. Food and Drug Administration regarding its New Drug Application for APF530 in the prevention of both acute and delayed onset chemotherapy-induced nausea and vomiting.

19 Mar 2010

Legacy Biotechnologies commences production of Reme-Flu

Nuvilex, Inc., announces today that Legacy Biotechnologies, Inc., its joint venture partner in Reme-Flu™, has commenced production of Reme-Flu™ and expects it to be ready for consumer purchase within the next 30 days. Reme-Flu™ is Legacy Biotechnologies’ unique 2-part homeopathic flu remedy designed to help treat symptoms of the flu. Initially, Reme-Flu™ will be offered on the top-rated website, www.nutralegacy.com.

18 Mar 2010

USPTO allows Regulus Therapeutics' claims covering methods of antagonizing miR-181a for regulating immune response

Regulus Therapeutics Inc. announced today that the United States Patent and Trademark Office (USPTO) has allowed claims in U.S. Application Serial No. 11/977,506 covering methods of antagonizing miR-181a to regulate immune response. This patent is owned by Stanford University and licensed exclusively to Regulus. miR-181a has been shown to regulate the response of immune cells, such as T lymphocytes, to specific stimuli and modulation of miR-181a could lead to a novel treatment of inflammatory disease.

18 Mar 2010

Having lower TSH levels while taking thyroxine replacement is not detrimental to health, says study

New research shows that it may be safe for patients taking thyroxine replacement to have low but not suppressed thyroid stimulating hormone (TSH) levels. The research, presented at the Society for Endocrinology BES meeting in Manchester, shows for the first time that it may be safe for patients to take slightly higher doses of thyroxine than are currently recommended.

18 Mar 2010

LSUHSC: Differences in drug metabolism can lead to differences in the effectiveness of candidate drug

Research led by Wayne L. Backes, PhD, Professor of Pharmacology and Associate Dean for Research at LSU Health Sciences Center New Orleans School of Medicine, has found that drug metabolism depends not only upon which enzymes are present in an individual, but also how they interact, and that can be the difference in whether a drug is safely eliminated from the body or is converted into a toxic or carcinogenic byproduct.

18 Mar 2010

Metabolism News and Research

Latest Metabolism News and Research

Working of master regulator protein phosphatase 1

Sirolimus-based immunosuppression improves survivals after transplantation for HCC

Changing drug therapy can help breast cancer patients get full benefit of tamoxifen treatment

Standard HCV therapy less effective in urban minority patients: Study

AVASTIN receives Health Canada approval for patients with GBM

Findings suggest adipose inflammation is necessary for fat cell turnover

Changing drug therapy can help breast cancer patients get full benefit of Tamoxifen

Bariatric surgery may delay onset of type 2 diabetes, says study

Breathing diesel exhaust during pregnancy linked with sluggishness in offspring

CTSI licenses GeneGo's pathway analysis suite and database searching tool

Researchers investigate link between consumption of high-fructose corn syrup and obesity

Novo Nordisk Foundation donates $160M to University of Copenhagen for metabolic research

Walnuts affect genes related to prostate tumor growth: Study

Legacy Biotechnologies, Phillips Sales and Marketing reach agreement to distribute Reme-Flu remedy

High dose of Zocor could lead to muscle injury, warns FDA

A.P. Pharma's NDA for APF530 in prevention of CINV: FDA issues Complete Response Letter

Legacy Biotechnologies commences production of Reme-Flu

USPTO allows Regulus Therapeutics' claims covering methods of antagonizing miR-181a for regulating immune response

Having lower TSH levels while taking thyroxine replacement is not detrimental to health, says study

LSUHSC: Differences in drug metabolism can lead to differences in the effectiveness of candidate drug

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves