Metabolism News and Research

Latest Metabolism News and Research

Sigma Life Science extends portfolio of knockout rat models with the release of ADME/Tox applications

Sigma® Life Science, an innovative brand of Sigma-Aldrich®, today extended its portfolio of knockout rat models with the announcement of a new suite of models designed to facilitate more predictive absorption, distribution, metabolism, excretion and toxicity (ADME/Tox) studies.

8 Mar 2010

Roche, OrbiMed, McKinsey announce fifteen finalists of SEED Competition

Roche, OrbiMed, and McKinsey announced fifteen finalists of the SEED Competition at the SEED Finalist Coaching Day event in Shanghai’s Zhangjiang Hi-Tech Park on March 2, 2010. The event was managed and presented by ChinaBio® Accelerator. The finalists will go on to compete for the grand prize of RMB 300,000 to be presented at the SEED Final Competition and Award Ceremony in Shanghai on April 23, 2010.

6 Mar 2010

Study shows clear link between Vitamin D levels and accumulation of fat in muscle tissue

There's an epidemic in progress, and it has nothing to do with the flu. A ground-breaking study published in the March 2010 Journal of Clinical Endocrinology and Metabolism found an astonishing 59 per cent of study subjects had too little Vitamin D in their blood. Nearly a quarter of the group had serious deficiencies (less than 20 ng/ml) of this important vitamin.

6 Mar 2010

68th AAD Annual Meeting reveals science behind skin care

Research presented by P&G Beauty & Grooming scientists at the 68th Annual Meeting of the American Academy of Dermatology (Miami Beach, FL, March 5-9) examines skin care science from multiple perspectives, offering insights into how ingredient formulations, care regimens and gene expressions impact skin condition.

6 Mar 2010

Data to advance the diagnosis, treatment and management of MH to be presented

Travel Award Available to share data with Clinicians and Scientists to advance the diagnosis, treatment, and management of Malignant Hyperthermia-Susceptible Patients April 23-24, 2010 at Mercy Hospital University of Pittsburgh Medical Center.

5 Mar 2010

AB SCIEX collaborates with Mass Spectrometry Centre to improve drug discovery and development

AB SCIEX, a global leader in life science analytical technologies, today announced that it is collaborating with the University of Geneva’s Mass Spectrometry Centre to create new workflows and analytical strategies intended to significantly improve drug discovery and development.

4 Mar 2010

MHAUS introduces new MH Mock Drill Training Kit to better prepare for MH emergencies

The Malignant Hyperthermia Association of the United States introduces a new MH Mock Drill Training Kit for Operating Room Staff to better prepare for MH emergencies

4 Mar 2010

Blood glucose-lowering hormone FGF21 also activates brown adipose tissue metabolism

The blood glucose-lowering hormone FGF21 is also an activator of brown adipose tissue metabolism, according to the study featured on the cover of Cell Metabolism and directed by the lecturer Francesc Villarroya of the UB's Department of Biochemistry and Molecular Biology (Faculty of Biology), the Institute of Biomedicine, and the Biomedical Research Networking Centre in Physiopathology of Obesity and Nutrition.

3 Mar 2010

"Stem cells in drug discovery and development" workshop to be held during toxicology annual meeting

Cellular Dynamics International (CDI) and Hoffmann-La Roche Inc. (Roche) today announced a workshop to be held during the Society of Toxicology Annual Meeting in Salt Lake City, UT, on March 7 - 11.

3 Mar 2010

European Journal of Drug Metabolism and Pharmacokinetics to be published by Springer

Starting in 2010, Springer will publish the European Journal of Drug Metabolism and Pharmacokinetics. All aspects of drug delivery and bioavailability are covered in the journal, which was previously published by the Swiss publisher M-decine & Hygi-ne. The journal was founded in 1975 by the late Professor Achille Benakis at the University of Geneva, Switzerland, and through the years gathered a loyal community of authors and readers.

3 Mar 2010

Merck’s MF/F Phase III study data presented at AAAAI annual meeting

Data from two Phase III studies of Merck’s investigational fixed-dose combinations of mometasone furoate and formoterol fumarate (MF/F) were presented by researchers today in two poster presentations at the American Academy of Allergy, Asthma & Immunology (AAAAI) annual meeting.

3 Mar 2010

Not getting enough sleep can cause fat to accumulate around organs, say researchers

Not getting enough sleep does more damage than just leaving you with puffy eyes. It can cause fat to accumulate around your organs - more dangerous, researchers say, than those pesky love handles and jiggly thighs.

2 Mar 2010

Synta Pharmaceuticals receives FDA approval for resuming elesclomol clinical development

Synta Pharmaceuticals Corp., a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today reported that the U.S. Food and Drug Administration (FDA) has approved resuming clinical development of elesclomol, the Company's first-in-class oxidative stress inducer.

2 Mar 2010

High levels of anti-aging hormone may increase cancer mortality in older men

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), older men with high levels of the hormone IGF-I (insulin-like growth factor 1) are at increased risk of cancer death, independent of age, lifestyle and cancer history.

2 Mar 2010

$Visceral fat can increase fracture risk in obese teenage girls$

Visceral fat can increase fracture risk in obese teenage girls

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), obese teenage girls with a greater ratio of visceral fat (fat around internal organs) to subcutaneous fat (fat found just beneath the skin) are likely to have lower bone density than peers with a lower ratio of visceral to subcutaneous fat.

2 Mar 2010

Using genetic engineering techniques in pigs, scientists create new model of diabetes

The incidence of diabetes is rising worldwide. Using genetic engineering techniques in pigs, scientists at Ludwig-Maximilians-Universität in Munich have created a new model of this metabolic disorder, which recapitulates many features of the disease, and promises to contribute significantly to improvements in diagnosis and therapy.

1 Mar 2010

Short-term dose of losartan-M6PHSA reduces liver inflammation and fibrosis: Study

A recent study found that rats with advanced fibrosis that were administered a short-term dose of losartan-M6PHSA had reduced liver inflammation and fibrosis. Those animals treated with oral losartan alone did not experience a similar reduction in disease activity. Results of this study appear in the March issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.

1 Mar 2010

Study shows ghrelin prevents acute liver damage, reduces oxidative stress and inflammation

Spanish researchers determined that rats treated with recombinant ghrelin displayed a reduction in liver fibrosis. Ghrelin, a stomach hormone, reduced the amount of fibrogenic cells by 25% in the treated rodents. Research further showed ghrelin prevented acute liver damage and reduced oxidative stress and inflammation in the animal models.

1 Mar 2010

ADMET tester Absorption Systems joins Society of Toxicology as Affiliate

Absorption Systems, a leader in testing drugs for ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity), has joined the Society of Toxicology, the premier global professional association of toxicologists, as an SOT Affiliate. The firm, a contract research organization, has more than a decade of experience assisting pharmaceutical and biotechnology companies in determining which compounds in development should be advanced into clinical testing.

27 Feb 2010

University of Michigan Health System opens new facility for eye care, diabetes research

On March 1, the first eye patients will enter an innovative new $132 million facility that expands the University of Michigan Health System's capacity for eye care, research and education, and unites diabetes researchers as they work to accelerate the search for a cure and prevention of diabetes.

27 Feb 2010

Metabolism News and Research

Latest Metabolism News and Research

Sigma Life Science extends portfolio of knockout rat models with the release of ADME/Tox applications

Roche, OrbiMed, McKinsey announce fifteen finalists of SEED Competition

Study shows clear link between Vitamin D levels and accumulation of fat in muscle tissue

68th AAD Annual Meeting reveals science behind skin care

Data to advance the diagnosis, treatment and management of MH to be presented

AB SCIEX collaborates with Mass Spectrometry Centre to improve drug discovery and development

MHAUS introduces new MH Mock Drill Training Kit to better prepare for MH emergencies

Blood glucose-lowering hormone FGF21 also activates brown adipose tissue metabolism

"Stem cells in drug discovery and development" workshop to be held during toxicology annual meeting

European Journal of Drug Metabolism and Pharmacokinetics to be published by Springer

Merck’s MF/F Phase III study data presented at AAAAI annual meeting

Not getting enough sleep can cause fat to accumulate around organs, say researchers

Synta Pharmaceuticals receives FDA approval for resuming elesclomol clinical development

High levels of anti-aging hormone may increase cancer mortality in older men

Visceral fat can increase fracture risk in obese teenage girls

Using genetic engineering techniques in pigs, scientists create new model of diabetes

Short-term dose of losartan-M6PHSA reduces liver inflammation and fibrosis: Study

Study shows ghrelin prevents acute liver damage, reduces oxidative stress and inflammation

ADMET tester Absorption Systems joins Society of Toxicology as Affiliate

University of Michigan Health System opens new facility for eye care, diabetes research

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves