Metabolism News and Research

Latest Metabolism News and Research

Increased coffee consumption linked to reduced hepatic fibrosis

Researchers from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) determined that patients with chronic hepatitis C virus (HCV) who consumed more than 308 mg of caffeine daily had milder liver fibrosis. The daily amount of caffeine intake found to be beneficial is equivalent to 2.25 cups of regular coffee.

5 Jan 2010

ARYx Therapeutics receives guidance in writing from FDA on tecarfarin

ARYx Therapeutics, Inc., a biopharmaceutical company, today announced that is has received guidance in writing from the U.S. Food and Drug Administration (FDA) confirming that the existing development pathway remains acceptable to seek regulatory approval of ARYx’s novel anticoagulant agent, tecarfarin (ATI-5923).

5 Jan 2010

$HIV-infected postmenopausal women face higher risk for accelerated bone loss and fracture$

HIV-infected postmenopausal women face higher risk for accelerated bone loss and fracture

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), postmenopausal HIV-infected women have a high prevalence of low bone mineral density and high bone turnover placing them at high risk for future bone fractures.

5 Jan 2010

Bioject Medical Technologies collaborates with MPI Research to explore drug and device opportunities

Bioject Medical Technologies Inc. (OTCBB:BJCT), a leading developer of needle-free injection therapy systems, today announced that it has established a strategic alliance with MPI Research, a leading pre-clinical research organization with experience in the development of injectable therapeutics.

5 Jan 2010

Study shows significant benefit of hyperbaric oxygen therapy to improve brain metabolism

A 5-year study of patients with severe traumatic brain injury conducted at Hennepin County Medical Center in Minneapolis shows significant benefit of hyperbaric oxygen therapy to improve brain metabolism and its ability to recover from injury.

4 Jan 2010

CORE, a biopsychosocial treatment center for weight loss

Earlier this month, leaders in the treatment of weight related disorders and psychiatry joined forces under the Comprehensive Obesity Recovery Effort (CORE, LLC).

30 Dec 2009

TheScientist honors Seahorse Bioscience's XF96 Extracellular Flux Analyzer as a 2009 Top Ten Innovation

Seahorse Bioscience, Inc., leader in the design and development of instruments for measuring cellular bioenergetics, announced that TheScientist magazine cited their XF96 Extracellular Flux Analyzer as a 2009 Top Ten Innovation.

30 Dec 2009

Scientists develop straightforward technique to find ethnic origin of stem cells

An international team of scientists led by researchers at The Scripps Research Institute has developed a straightforward technique to determine the ethnic origin of stem cells.

30 Dec 2009

DMET genotyping platform screens for 1256 genetic variations in 170 genes

It's the ultimate goal in the treatment of cancer: tailoring a person's therapy based on his or her genetic makeup. While a lofty goal, scientists are steadily moving forward, rapidly exploiting new technologies. Researchers at Georgetown Lombardi Comprehensive Cancer Center report a significant advance in this field of research using a new chip that looks for hundreds of mutations in dozen of genes.

29 Dec 2009

Study suggests genetic variations predispose African-Americans to diabetes

For years, scientists have tried to determine the basis for discrepancies between race and the predisposition for development of diseases such as type II diabetes and cardiovascular disease. Could factors such as differences in lifestyle or access to health care play a role, or is there something else in play?

29 Dec 2009

Scientists identify new gene variants associated with disturbances in lipid metabolism

Scientists of Helmholtz Zentrum München led by Professor Karsten Suhre have identified new gene variants associated with disturbances in the lipid metabolism.

28 Dec 2009

CtIP protein plays a critical role in DNA repair

La Jolla, CA-In order to preserve our DNA, cells have developed an intricate system for monitoring and repairing DNA damage. Yet precisely how the initial damage signal is converted into a repair response remains unclear. Researchers at the Salk Institute for Biological Studies have now solved a crucial piece of the complex puzzle.

28 Dec 2009

Learning disabilities: Understanding the problem and managing the challenges

"Trying to address learning disabilities with innovative teaching methods and creative school financing is not the answer," said Etta Brown, a licensed educational psychologist, veteran social worker and author of "Learning Disabilities, Understanding the Problem and Managing the Challenges" from Langdon Street Press (www.understandingld.com).

24 Dec 2009

Tips to achieve fitness and weight loss goals

More than 100 million Americans made New Year resolutions for 2009, and four out of five were not able to stick with them, according to the third annual Franklin Covey New Year’s Resolution survey released in January 2009.

23 Dec 2009

Protein adenylyl cyclase senses and regulates pH blood levels

Researchers have identified the protein mechanism that senses bicarbonate fluctuations and adjusts blood pH levels.. A Canadian/U.S. research team led by University of Alberta biological sciences professor, Greg Goss and his graduate students Martin Tresguerres and Scott Parks achieved the first demonstration of the process in a whole animal. The researchers found that the protein adenylyl cyclase sensed and then regulated the pH blood levels in a dogfish shark following feeding.

23 Dec 2009

Heart and Stroke Foundation urges government to regulate trans fats in Canada's food supply

The Heart and Stroke Foundation calls on the federal government to live up to the commitment made two years ago to regulate trans fats in Canada's food supply, based on Health Canada's final set of monitoring results released today.

23 Dec 2009

High prevalence of type 2 diabetes may be linked to excess niacin intake

Facing the increasing prevalence of type 2 diabetes worldwide in the past few decades, one may ask what is wrong with humans. Geneticists tell us that the human genome has not changed markedly in such a short time.

23 Dec 2009

Endocannabinoid modulation of sweet taste receptors may help control feeding behavior

Sweet taste responses were enhanced by endocannabinoids in every case. The effect was specific for sweet taste, as endocannibinoids had no effect on responses to sour, salty, bitter or umami taste stimuli.

22 Dec 2009

Arena Pharmaceuticals submits lorcaserin NDA to the FDA

Arena Pharmaceuticals, Inc. announced today that it has submitted a New Drug Application (NDA) to the US Food and Drug Administration (FDA) for lorcaserin, Arena's internally discovered and developed drug candidate for weight management, including weight loss and maintenance of weight loss. The submission is based on an extensive data package from lorcaserin's clinical development program that includes 18 clinical trials totaling 8,576 patients.

22 Dec 2009

PGxHealth, DHZ announce collaboration in genetic variant study with response to clopidogrel

PGxHealth, a division of Clinical Data, Inc., today announced that it has established a research collaboration with Deutsches Herzzentrum (DHZ), Munich, Germany, to evaluate the predictive value of genetic markers, including PGxHealth proprietary markers, for response to clopidogrel (Plavix®).

22 Dec 2009

Metabolism News and Research

Latest Metabolism News and Research

Increased coffee consumption linked to reduced hepatic fibrosis

ARYx Therapeutics receives guidance in writing from FDA on tecarfarin

HIV-infected postmenopausal women face higher risk for accelerated bone loss and fracture

Bioject Medical Technologies collaborates with MPI Research to explore drug and device opportunities

Study shows significant benefit of hyperbaric oxygen therapy to improve brain metabolism

CORE, a biopsychosocial treatment center for weight loss

TheScientist honors Seahorse Bioscience's XF96 Extracellular Flux Analyzer as a 2009 Top Ten Innovation

Scientists develop straightforward technique to find ethnic origin of stem cells

DMET genotyping platform screens for 1256 genetic variations in 170 genes

Study suggests genetic variations predispose African-Americans to diabetes

Scientists identify new gene variants associated with disturbances in lipid metabolism

CtIP protein plays a critical role in DNA repair

Learning disabilities: Understanding the problem and managing the challenges

Tips to achieve fitness and weight loss goals

Protein adenylyl cyclase senses and regulates pH blood levels

Heart and Stroke Foundation urges government to regulate trans fats in Canada's food supply

High prevalence of type 2 diabetes may be linked to excess niacin intake

Endocannabinoid modulation of sweet taste receptors may help control feeding behavior

Arena Pharmaceuticals submits lorcaserin NDA to the FDA

PGxHealth, DHZ announce collaboration in genetic variant study with response to clopidogrel

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves