Metabolism News and Research

Latest Metabolism News and Research

Social isolation and stress can raise breast cancer risk

Social isolation and related stress could contribute to human breast cancer susceptibility, research from a rat model designed at the University of Chicago to identify environmental mechanisms contributing to cancer risk shows.

8 Dec 2009

Positive clinical data from Phase II study of elacytarabine in patients with AML reported

Clavis Pharma ASA announces that positive clinical data from its Phase II study with its lead cancer product candidate elacytarabine in patients with late-stage acute myeloid leukaemia (AML) was presented at the 51st American Society of Hematology (ASH) Annual Meeting in New Orleans, LA, USA.

7 Dec 2009

Study explains how circadian rhythms can drive feeding and metabolism behaviors

One of the pioneers in research on sleep:wake circadian genes, Amita Sehgal, Ph.D., has discovered that fruit flies' appetite and consumption are controlled by two rival sets of clocks, one in neurons and the other in the fly fat body, which is analogous to the liver.

6 Dec 2009

Introduction of the Endocrine Disruption Prevention Act of 2009 commended

The Endocrine Society commends Representative Jim Moran (D-VA) and Senator John Kerry (D-MA) for introducing the Endocrine Disruption Prevention Act of 2009 (H.R. 4190; S. 2828). The bill, endorsed by the Society, amends the Public Health Service Act by authorizing the National Institute of Environmental Health Sciences to conduct a research program on endocrine disruption aimed at preventing and reducing the production of and the public's exposure to harmful chemicals.

5 Dec 2009

Call for every health insurance plan to cover Phenylketonuria

Credit Senators John Kerry (D-MA) and Robert Casey (D-PA) with a significant contribution to the health care debate: a bill ends a glaring disparity in the way Americans living with Phenylketonuria (PKU) control their potentially devastating disease, and the way others living with serious chronic conditions are treated. "The Medical Foods Equity Act of 2009" aims to save affected families thousands of dollars in out-of-pocket costs, cut long-term costs for the entire system, and offer 20,000 Americans a better shot at healthy, happy, and productive lives.

5 Dec 2009

Absorption Systems opens renovated AAALAC-accredited GLP surgical suite for medical device testing

Absorption Systems, a leader in testing drugs for ADMET (absorption, distribution, metabolism, excretion and toxicity), today introduced an extensively renovated surgical suite for preclinical medical device testing at the company’s facility in San Diego, CA. Absorption Systems has long been recognized as a leader in drug testing and is experiencing increased demand for its medical device testing services as well.

4 Dec 2009

Researchers discover mechanism that explains how chromosomal translocations are not random

Researchers at the UC San Diego School of Medicine have pinpointed a mechanism that may help explain how chromosomal translocations - the supposedly random shuffling of large chunks of DNA that frequently lead to cancer - aren't so random after all. They have developed a model of such chromosomal mix-ups in prostate cancer which indicates that the male sex hormone (androgen) receptor unexpectedly plays a key role in driving specific translocations in the development of cancer.

4 Dec 2009

Santaris Pharma's LNA technology based microRNA-targeted therapy holds promise for HCV

A study published online in this week's Science shows that SPC3649, a breakthrough microRNA-targeted therapy developed by Santaris Pharma A/S using its proprietary Locked Nucleic Acid (LNA) technology, holds promise as a novel treatment for patients infected with the Hepatitis C virus (HCV).

4 Dec 2009

Breastfeeding a child may lower a woman's risk of developing Metabolic Syndrome

Breastfeeding a child may lower a woman's risk of developing Metabolic Syndrome, a condition linked to heart disease and diabetes in women, according to a Kaiser Permanente study that was published today online ahead of print and will appear in the February issue of Diabetes, a journal of the American Diabetes Association.

4 Dec 2009

Breastfeeding reduces a woman's risk of developing Metabolic Syndrome

3 Dec 2009

Body needs fasting periods to stay healthy

A body that is provided with food too often gets caught up in the maelstrom of a lack of exercise, obesity and ultimately diabetes. The trigger is a molecular switch that is controlled by insulin, a new study by scientists from ETH Zurich has revealed.

3 Dec 2009

Roche to provide the RealTime ready Influenza A/H1N1 Detection Set to CLIA high-complexity labs under EUA

The Roche assay for the 2009 H1N1 influenza virus detects RNA from the 2009 H1N1 Influenza A virus and provides a rapid means of identification of patients infected with this virus. In order to ensure continued specificity and sensitivity of the Roche's Influenza A/H1N1 assay, Roche performs sequence comparisons with all available 2009 H1N1 Influenza Virus sequences on a regular basis.

3 Dec 2009

Manpei Suzuki Diabetes Foundation announces the 2009 winner of International Prize

The Manpei Suzuki Diabetes Foundation is pleased to announce the 2009 winner of the International Prize: Donald F. Steiner, MD, A. N. Pritzker Distinguished Service Professor Emeritus, Departments of Medicine and Biochemistry and Molecular Biology, The University of Chicago, USA.

3 Dec 2009

Roche ships additional quantities of Tamiflu oral suspension

Roche announced today that it has begun shipping additional quantities of Tamiflu® (oseltamivir phosphate) oral suspension (liquid).

3 Dec 2009

New book presents latest research on neuroendocrine physiology

In this volume an international group of basic and clinical investigators presents their latest research on neuroendocrine physiology, advances in the control of the onset of puberty and its disorders, and basic and clinical aspects of the GH/IGF-1 and hypothalamic-pituitary-adrenal axes. An entire section is dedicated to pituitary tumors, including genetics and neuroimaging, and another covers the neuroendocrine control of substrate metabolism, including hypothalamic obesity and anorexia.

3 Dec 2009

Researchers to publish a paper on the availability of 'Spice' drugs online

A paper to be published this month by University of Hertfordshire researchers about the availability of 'Spice' drugs online will raise new concerns about its mood altering effects.

3 Dec 2009

Fruit flies use same molecular mechanisms as humans for maintaining cholestrol

More importantly, according to two new studies led by a University of Utah human geneticist, fruit flies use the same molecular mechanisms as humans to help maintain proper balances of cholesterol and a key form of stored fat that contributes to obesity. The findings mean that as researchers try to learn more about the genetic and biological processes through which people regulate cholesterol and fat metabolism, the humble fruit fly, also called Drosophila, can teach humans much about themselves.

2 Dec 2009

Over twenty new drug metabolism assays launched by Absorption Systems

Absorption Systems, a leader in drug safety and ADMET (absorption, distribution, metabolism, excretion and toxicity) testing, today announced the introduction of a more complete series of drug metabolism assays designed to support the pharmaceutical R&D process, from early-stage discovery through late-stage clinical development.

2 Dec 2009

World’s first 1000 MHz ultra-high field NMR AVANCE spectrometer installed at CRMN, France

Bruker BioSpin has successfully completed the installation of the world’s first 1000 MHz ultra-high field NMR AVANCE™ spectrometer at the Centre de Resonance Magnétique Nucléaire à Très Hauts Champs (CRMN) in Lyon, France (a joint research unit of CNRS, Ecole Normale Supérieure de Lyon and Université Lyon 1).

2 Dec 2009

FDA approves additional intended use of Roche's cobas TaqScreen MPX Test

Roche announced today that the United States Food & Drug Administration (FDA) approved an additional intended use for its licensed nucleic acid test, to screen source plasma in pools comprised of up to 96 individual donations. The test, called the cobas® TaqScreen MPX Test for use on the cobas s 201 system, is a qualitative, in-vitro test for the simultaneous, direct detection of the human immunodeficiency virus (HIV-1 Group M RNA, HIV-1 Group O RNA , HIV-2 RNA), hepatitis C virus RNA and hepatitis B virus DNA in human plasma.

From Roche Sequencing and Life Science 2 Dec 2009

Metabolism News and Research

Latest Metabolism News and Research

Social isolation and stress can raise breast cancer risk

Positive clinical data from Phase II study of elacytarabine in patients with AML reported

Study explains how circadian rhythms can drive feeding and metabolism behaviors

Introduction of the Endocrine Disruption Prevention Act of 2009 commended

Call for every health insurance plan to cover Phenylketonuria

Absorption Systems opens renovated AAALAC-accredited GLP surgical suite for medical device testing

Researchers discover mechanism that explains how chromosomal translocations are not random

Santaris Pharma's LNA technology based microRNA-targeted therapy holds promise for HCV

Breastfeeding a child may lower a woman's risk of developing Metabolic Syndrome

Breastfeeding reduces a woman's risk of developing Metabolic Syndrome

Body needs fasting periods to stay healthy

Roche to provide the RealTime ready Influenza A/H1N1 Detection Set to CLIA high-complexity labs under EUA

Manpei Suzuki Diabetes Foundation announces the 2009 winner of International Prize

Roche ships additional quantities of Tamiflu oral suspension

New book presents latest research on neuroendocrine physiology

Researchers to publish a paper on the availability of 'Spice' drugs online

Fruit flies use same molecular mechanisms as humans for maintaining cholestrol

Over twenty new drug metabolism assays launched by Absorption Systems

World’s first 1000 MHz ultra-high field NMR AVANCE spectrometer installed at CRMN, France

FDA approves additional intended use of Roche's cobas TaqScreen MPX Test

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves