Metabolism News and Research

Latest Metabolism News and Research

The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis

An imbalance in the lipid content of the liver appears to trigger the downward spiral that leads some with fatty liver disease to advance to full-blown liver failure, according to a new study in the May Cell Metabolism.

11 May 2006

Ghrelin involved in development of diabetes

Ghrelin, a hormone long considered a key player in obesity, may instead take a major role in maintaining the balance between insulin and glucose and the development of diabetes, said Baylor College of Medicine researchers in a report in the current issue of the journal Cell Metabolism.

11 May 2006

Cancer treatment interferes with bone development

According to researchers in the U.S. the cancer drug Gleevec (imatinib), which has dramatically improved survival prospects for some cancer patients, can interfere with bone development.

11 May 2006

Testosterone patches help women with under-active pituitary glands

New research published in The Journal of Clinical Endocrinology & Metabolism showed the first positive effect of testosterone on bone density, body composition and emotional, cognitive and behavioral function in women with low testosterone levels resulting from under-active pituitary glands.

10 May 2006

Neurons can produce Alzheimer's-linked apolipoprotein E

A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco.

10 May 2006

Gene "CGI-58" linked to rare disease activates fat breakdown

A gene earlier linked to a rare disease plays a critical role in the body's "finely tuned balance" of fat storage and break down, new evidence reported in the May Cell Metabolism reveals.

10 May 2006

Genetic analysis of opioid-induced hyperalgesia

In findings published in Nature Biotechnology (May 2006, vol. 24 No. 5), Roche scientists present a new method for analyzing the metabolism of a commonly prescribed drug.

10 May 2006

European Food Safety Authority says Aspartame quite safe to use

According to the European Food Safety Authority (EFSA), on the basis of all the currently available evidence, a further review of the safety of aspartame is not necessary.

9 May 2006

Brain scan could reveal who will get Alzheimer's disease

According to researchers in California, a brain scan may possibly identify structural and metabolic brain changes that predict dementia or cognitive decline in normal older adults.

3 May 2006

Identification of CPT1c gene that the brain needs to manage body weight

Working with genetically engineered mice, Johns Hopkins scientists have interfered with the brain's ability to control an animal's response to a high-fat diet.

3 May 2006

Researchers recommend national uniform newborn screening tests

In a new study, conducted for the federal government and published in a supplement to the May issue of the journal Pediatrics, Stephen M. Downs, M.D. and Aaron E. Carroll, M.D., of the Indiana University School of Medicine, recommend a national uniform panel of newborn screening tests which they found to be cost saving as well as life saving.

3 May 2006

Scientists discover a master key to microbes' pathogenic lifestyles

For some microbes, the transformation from a benign lifestyle in the soil to that of a potentially deadly human pathogen is just a breath away.

3 May 2006

Simple formula that will enable anesthesiologists to predict blood needs in heart surgery

Duke University Medical Center researchers have developed a simple formula that will enable anesthesiologists to predict, based on individual patient characteristics, how much blood to have on hand in the operating room prior to coronary artery bypass surgery.

3 May 2006

New method could predict individual patient responses to drug treatments

Scientists from Imperial College London and Pfizer have developed a new method that could predict individual patient responses to drug treatments. The authors anticipate that the development will advance biomedical research further towards development of personalised medicines.

28 Apr 2006

Enzyme discovery could reduce Kaposi sarcoma tumour growth and lead to drugs suitable for treating other viral cancers

A report in the Journal of Biological Chemistry shows that inhibition of heme oxygenase-1, an enzyme involved in iron metabolism, reduces Kaposi sarcoma tumor growth. This discovery could result in the production of new drugs to treat this and other viral cancers.

28 Apr 2006

HRT can reduce heart attacks by about one-third in women under age 60

For the last few years, women have heard conflicting reports about the risks and benefits of hormone replacement therapy (HRT). A new study that analyzes many trials together concludes that HRT can reduce heart attacks by about one-third in women under age 60 but has mixed results for older women.

23 Apr 2006