Metabolism News and Research

Latest Metabolism News and Research

Combined computed tomography (CT) and positron emission tomography (PET) - may detect the spread of head and neck cancer more accurately

"PET/CT is very helpful in determining where we should pinpoint our biopsies for recurrent disease," said Dr. Carol Shores, assistant professor of otolaryngology/head and neck surgery at UNC and the report's senior author. Shores is a member of the UNC Lineberger Comprehensive Cancer Center.

26 Jul 2005

Loyola researchers hope that zoledronic acid will be effective and safe for patients with inflammatory bowel diseases (IBD)

Researchers at the Osteoporosis and Metabolic Bone Disease Center and the Division of Gastroenterology at Loyola University Health System are studying a once-yearly, 15-minute infusion of an intravenous (IV) medication in patients with osteopenia (low bone mass) and inflammatory bowel diseases (IBD) that, if proven effective, may be considered the standard of treatment.

26 Jul 2005

Direct relationship between inflammation and glucose levels

Scientists at Galileo Pharmaceuticals, Inc. have demonstrated a direct relationship between inflammation and glucose levels. Through its recently established metabolic disease program, Galileo confirmed in preclinical models that inhibiting lipoxygenases, known mediators of inflammatory response, significantly lowers blood glucose levels in animal models of diabetes.

26 Jul 2005

Study offers a unique perspective on the beginnings of the alcohol experience and usage patterns of 12-year-olds

Clues looking into the root causes of alcoholism are emerging from new findings that center on the genetic patterns of young drinkers, with particular focus on why adolescents are more likely to drink large quantities of alcohol even if they need more alcohol to get the effects they desire.

25 Jul 2005

Researchers have identified 23 new longevity genes

Researchers have identified 23 new longevity genes by screening the genome of Caenorhabditis elegans, a small worm that is used as a model organism in genetics studies. The findings are reported in the inaugural issue of PLoS Genetics.

25 Jul 2005

Researchers discover type of "fuel" that the heart uses can contribute to the severity of heart failures

Researchers have determined how metabolic pathways differ between healthy and failing hearts. Normally, a heart derives its energy from a balance of fatty acids and carbohydrates, specifically glucose.

21 Jul 2005

Heart attack patients: shedding pounds reduces risks

Heart attack patients with diabetes or a cluster of cardiovascular risk factors known as metabolic syndrome have an increased risk of another heart attack, stroke or death, but patients who lost weight after their heart attacks were less likely to become diabetic, according to a new study in the July 19, 2005, issue of the Journal of the American College of Cardiology.

21 Jul 2005

Imiquimod and fluorouracil emerge as effective weapons for treating superficial basal cell carcinomas

Basal cell carcinoma, a type of skin cancer, affects millions of people worldwide. While traditional treatment has been surgery and radiation, topical treatments in combination with surgery are showing more promise for patients with basal cell carcinoma.

21 Jul 2005

Protein found in fat cells is a newly discovered cause of insulin resistance

A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has shown that a protein found in fat cells is a newly discovered cause of insulin resistance, establishing a previously unidentified molecular link between obesity and type 2 diabetes and offering a potential new target for the development of drugs to treat diabetes.

20 Jul 2005

SIRT1 gene suppresses longevity

Researchers have determined that a gene present in mouse cells limits the number of times that a cell can divide. The gene is involved in a process, called senescence, which is thought to ensure that aging cells do not pass on harmful mutations.

20 Jul 2005

Insulin keeps fat in the liver under control

Insulin, a hormone long recognized as a generator of fat, also keeps fat in the liver under control, according to a new study in the July issue of Cell Metabolism.

19 Jul 2005

Variant of a common protein plays a primary role in Type 2 diabetes and obesity

Scientists in France and the United States report that a variant of a common protein plays a primary role in Type 2 diabetes and obesity, key features of the "insulin resistance syndrome" that affects more than 50 million people in this country and a similar number in Europe.

19 Jul 2005

Genome studies may help target new drugs to fight them

One parasite causes a deadly sleeping sickness in Africa. The second damages the internal organs of millions of Latin Americans. The third causes terrible lesions on the face or limbs of victims from Brazil to India.

18 Jul 2005

New molecular insights may one day lead to opportunities to stave off old age

Delving deep into the molecular subtleties of a strain of mice engineered to age rapidly, scientists have found that an accumulation of genetic mutations prompts a cascade of programmed cell death that seems to underpin the aging process.

18 Jul 2005

Scientists sequence the genomes of three species of parasites responsible for causing diseases that kill or cripple millions

Howard Hughes Medical Institute (HHMI) scientists who participated in the project say the sequencing of the genomes of the parasitic protozoa that cause Chagas disease, African sleeping sickness, and leishmaniasis, could significantly impact world health. Some of the genes discovered may prove to be good drug and vaccine targets.

17 Jul 2005

Individuals with inactive heterozygous ALDH2, a tendency to alcohol flushing have a greater susceptibility to hangovers

Alcohol consumption is an integral part of the Japanese business culture. Hangovers, however, can have substantial economic drawbacks.

17 Jul 2005

Growing body of evidence indicating that childhood obesity is linked to a lack of exercise

A study published by the medical journal The Lancet dealt another blow to the "food police" and the trial lawyers seeking to blame food for the nation's expanding waistline.

15 Jul 2005

New insights into brain cell metabolism from PET and MRI scans

By discovering a crucial piece of submicroscopic information about how the brain converts fuel into energy for neurons, Cornell University biophysicists have gleaned new insights into brain cell metabolism that will allow neurologists to better interpret data from such diagnostic tests as positron emission tomography (PET) scans and a specialized magnetic resonance imaging (MRI) test.

12 Jul 2005

Discovery of protein deficit that causes drug toxicity

Mayo Clinic researchers have discovered an inherited structural mechanism that can make drugs for some diseases toxic for some patients.

11 Jul 2005

Fat adults more likely to have increased insulin resistance, a risk marker for Type 2 diabetes

Adult lifestyle has more influence on your chances of developing diabetes than childhood experience, according to new research whose findings contradict previously-held beliefs.

6 Jul 2005

Metabolism News and Research

Latest Metabolism News and Research

Combined computed tomography (CT) and positron emission tomography (PET) - may detect the spread of head and neck cancer more accurately

Loyola researchers hope that zoledronic acid will be effective and safe for patients with inflammatory bowel diseases (IBD)

Direct relationship between inflammation and glucose levels

Study offers a unique perspective on the beginnings of the alcohol experience and usage patterns of 12-year-olds

Researchers have identified 23 new longevity genes

Researchers discover type of "fuel" that the heart uses can contribute to the severity of heart failures

Heart attack patients: shedding pounds reduces risks

Imiquimod and fluorouracil emerge as effective weapons for treating superficial basal cell carcinomas

Protein found in fat cells is a newly discovered cause of insulin resistance

SIRT1 gene suppresses longevity

Insulin keeps fat in the liver under control

Variant of a common protein plays a primary role in Type 2 diabetes and obesity

Genome studies may help target new drugs to fight them

New molecular insights may one day lead to opportunities to stave off old age

Scientists sequence the genomes of three species of parasites responsible for causing diseases that kill or cripple millions

Individuals with inactive heterozygous ALDH2, a tendency to alcohol flushing have a greater susceptibility to hangovers

Growing body of evidence indicating that childhood obesity is linked to a lack of exercise

New insights into brain cell metabolism from PET and MRI scans

Discovery of protein deficit that causes drug toxicity

Fat adults more likely to have increased insulin resistance, a risk marker for Type 2 diabetes

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research