Metabolomics News and Research

Latest Metabolomics News and Research

Mechanism of action of the anti-cancer drug GMX1778 identified

Metabolon, Inc., the leader in metabolomics-driven biomarker discovery and analysis, today announced a new study has been published identifying the mechanism of action of the anti-cancer drug GMX1778. Co-authored by scientists at Gemin X Pharmaceuticals and Metabolon, the paper “The Small Molecule GMX1778 is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in NAPRT1-Deficient Tumors” appears online ahead of print in Molecular and Cellular Biology.

17 Sep 2009

Metabolon awarded patent for metabolomics software

Metabolon, Inc. has announced that it has been awarded a patent for its metabolomics software, Ion Tracker™, which provides a mechanism for creating new chemical library entries.

11 Aug 2009

New approach to prostate cancer detection - Sarcosine may distinguish between slow-growing and aggressive prostate cancers

On Friday 20 March, US researcher Dr. Chris Beecher from the University of Michigan gave a well attended lecture about sarcosine, an N-methyl derivative of the amino acid glycine, at the 24th Annual EAU Congress in Stockholm, Sweden.

25 Mar 2009

A new method for assessing women’s eggs could enhance IVF success

Many couples who have trouble conceiving a child have turned to a process known as in vitro fertilization.

23 Mar 2009

Discovery of new prostate cancer marker

Howard Hughes Medical Institute researchers have identified a new biological marker present in the urine of patients with prostate cancer that indicates whether the cancer is progressing and spreading.

15 Feb 2009

Compound can distinguish between benign tissue and localized and metastatic prostate cancer

Researchers have determined that a molecule produced by the bodys metabolism could be used to differentiate between benign prostate tissue vs. localized and metastatic prostate cancer.

11 Feb 2009

Breakthrough on type 1 diabetes development

Finnish scientists have reported a breakthrough in the attempts to understand the development of type 1 diabetes.

17 Dec 2008

Study identifies genetic variants giving rise to differences in metabolism

Common genetic polymorphisms induce major differentiations in the metabolic make-up of the human population, according to a paper published November 28 in the open-access journal PLoS Genetics.

28 Nov 2008

Existing anti-obesity drugs may be effective against flu, hepatitis and HIV

Viruses dramatically increase cellular metabolism, and existing anti-obesity drugs may represent a new way to block these metabolic changes and inhibit viral infection, according to a study published today in the journal Nature Biotechnology.

29 Sep 2008

Babies from frozen embryos less likely to be premature

A Danish study has found that IVF babies born from embryos that are frozen are less likely to be underweight or premature than those conceived during fresh treatment cycles.

9 Jul 2008

European research project to explore Alzheimer's diagnosis

VTT Technical Research Centre of Finland, GE Healthcare, a division of the General Electric Company (NYSE: GE) and a Consortium of leading research institutions across Europe announced the PredictAD project, a research collaboration aimed at developing new diagnostic procedures for patients with Alzheimer's disease.

10 Jun 2008

Blood test for Parkinson's shows promise

A test that profiles molecular biomarkers in blood could become the first accurate diagnostic test for Parkinson's disease, new research shows.

12 Mar 2008

Discovery of new ALS gene

The ALS research team at Umea University in Sweden, working with Dutch and Belgian colleagues, has found new connections between mutations in gene DPP6 and contracting the non-hereditary form of ALS. The findings are being published december 16 in Nature Genetics on the Web.

18 Dec 2007

Research programme for foods and services promoting well-being

One of the challenges facing the food industry is how to create tasty, convenient and experiential products made from health promoting ingredients.

31 Oct 2007

Diet and medications may assist prevention of prostate cancer

Recent investigations of medications, diet and the molecular understanding of prostate cancer are defining potential prevention strategies for the disease, and herald a new stage in the management of this cancer, according to a new review.

25 Sep 2007

Imaging is everything: What the clinician needs to know

In recent years, the concept of multimodality imaging has emerged coincident with advances in the newer technologies of Cardiac Magnetic Resonance (CMR) and Coronary Computed Tomography (CCT).

3 Sep 2007

New method for early disease diagnosis

Purdue University researchers worked with the Indiana University School of Medicine to establish a technique that provides a new approach for detecting a number of genetic disorders found in infants and young children.

18 Jul 2007

Chemical maps hint at drug's effects on schizophrenia

Antipsychotic drugs do most of their work in the brain, but they also leave behind in the bloodstream a trail of hundreds of chemicals that may be used in the future to direct better treatment for schizophrenia and other psychiatric conditions, say Duke University Medical Center researchers.

16 May 2007

Important new discovery in metabolomics

St. Jude investigators have mapped out many of the dynamic genetic and biochemical changes that make up a cell's response to a shortage of a molecule called Coenzyme A (CoA), a key player in metabolism.

27 Apr 2007

Twin study on the increased cardiometabolic risk in obesity

A unique monozygotic twin study by researchers from the Finnish Twin Cohort, Helsinki University Central Hospital, and VTT Technical Research Centre of Finland found that obesity, already in its early stages and independent of genetic influences, is associated with deleterious alterations in the lipid metabolism known to facilitate atherogenesis, inflammation and insulin resistance.

15 Feb 2007