Metabolomics

Metabolomics is a field of research that focuses on the chemical processes undergone by metabolites. It involves the use of sophisticated analytical technologies to identify and quantify cellular metabolites, in addition to the extraction of relevant information so that the data can be interpreted and applied in a practical setting.

Applications of Metabolomics

The field of metabolomics has the potential to be applied in a number of settings to offer practical use. It remains a relatively young field of research and, therefore many of its applications of metabolomics are still only becoming evident. Nonetheless, this article covers some of the present and future ways in which metabolomics could be applied.

What are Metabolites?

History of Metabolomics

Analyzing Metabolomics Data

Targeted Metabolomics

Metabolomics in Plants

Challenges in Targeted Metabolomics

The Metabolome: An Overview

Metabolomics in Organ Transplantation

Metabolomics in Clinical Chemistry

Metabolomics in Pharmacology

Metabolic Changes in Aging Cells

See more featured articles »

Metabolomic Profiling for Disease Diagnosis

Techniques Used in Targeted Metabolomic Profiling

Metabolomic Profiling of an Ancient Herbal Medicine using UHPLC

Metabolomic Profiling of Ricin

Lipid Metabolism and the Gut Microbiota

Latest Metabolomics News and Research

Gut microbes and metabolites reveal how lifestyle changes help prevent type 2 diabetes

Researchers identified 502 blood metabolites linked to prediabetes and type 2 diabetes, with 143 tied to the gut microbiome. The study shows how lifestyle interventions like diet and exercise can modify metabolomic profiles to support glucose control.

9 Apr 2025

Gut bacteria and blood metabolites directly affect children’s height, study finds

Researchers used Mendelian randomization to uncover causal links between gut microbiota, blood metabolites, and short stature in children.

7 Apr 2025

How your dairy choices could impact your risk of type 2 diabetes, new study shows

A study of Swedish adults finds that high intake of non-fermented milk and cheese increases the risk of type 2 diabetes, while fermented milk, cream, and butter offer protective benefits.

7 Apr 2025

Caffeine and beetroot juice beat fatigue in repeated high-intensity runs

Caffeine combined with beetroot juice significantly improves both initial and repeated 1000-meter running performance in non-athlete men. Body fat percentage, sleep duration, and nutrition emerge as key factors influencing endurance outcomes.

30 Mar 2025

Duke-NUS and NUS Medicine launch first-ever joint center to drive metabolomics research

In a strategic move for medical research and innovation, Duke-NUS Medical School and the National University of Singapore Yong Loo Lin School of Medicine (NUS Medicine) have launched the Systems Metabolomics Centre (SysMeC), their first-ever joint research center.

22 Mar 2025

AI predicts biological aging using steroid pathways

Researchers discuss a novel method to predict biological aging using a deep neural network based on pathways of steroidogenesis.

19 Mar 2025

Why do some people need supplements and others don’t? New review explains

New research in The New England Journal of Medicine reviews current knowledge on micronutrient requirements, deficiencies, and interventions. It highlights the need for targeted supplementation and calls for advanced research to better diagnose and treat hidden deficiencies.

9 Mar 2025

Evaluating the combined effect of electroacupuncture and Chinese herbal medicine on gut microbiota in ALS patients

Recent studies have highlighted a link between amyotrophic lateral sclerosis (ALS) and gut microbiota. This prospective study aimed to evaluate the effects of electroacupuncture combined with Chinese herbal medicine on gut microbiota and metabolomics in ALS patients.

7 Mar 2025

Portion sizes vary worldwide, but science isn’t the reason—new study explains why

Researchers analyzed 96 national dietary guidelines and found that different methods used to determine portion sizes lead to minimal variation, with regional factors like cost and culture having a greater impact than methodology.

2 Mar 2025

Neurofilament light as a translational biomarker from preclinical drug discovery to clinical application

Neurofilament light (NFL) is a powerful and sensitive biomarker for tracking neuronal health and disease progression.

From Charles River Labs - Neuroscience Discovery Services 21 Feb 2025

Common antidepressant Fluoxetine protects from sepsis-induced death

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19 Feb 2025

Plant immune responses may offer insights into human brain diseases

A groundbreaking study led by a team of researchers at the University of Kentucky's Martin-Gatton College of Agriculture, Food and Environment has revealed a surprising biochemical connection between plant immune responses and human neurological health.

19 Feb 2025

Gut microbiome shifts from sugary drinks tied to higher diabetes risk

Researchers examine the association between sugar-sweetened beverage intake and gut microbiota-mediated changes that may mitigate the risk of diabetes.

7 Feb 2025

Single heat stroke exposure triggers long-term health risks and metabolic vulnerabilities

The study links exertional heat stroke to chronic disorders, revealing impacts on body mass regulation and heart health, especially in high-fat diet scenarios.

3 Feb 2025

Dietary intervention restores gut microbiome and offers protection against chronic diseases

Findings indicate that a microbiome restoration diet improves gut health and reduces chronic disease markers, highlighting its cardiometabolic benefits.

27 Jan 2025

Researchers elucidate the significance of birth in neural stem cell maintenance

A research group led by Kazunobu Sawamoto, a professor at Nagoya City University and National Institute for Physiological Sciences, and Koya Kawase, a pediatric doctor at Nagoya City University Hospital, has elucidated the significance of birth in the maintenance of neural stem cells (NSCs).

24 Jan 2025

New $20 million NIH grant aims to uncover the secrets of the human virome

Unlocking knowledge about the vast and varied collection of viruses that live in and on our bodies is the goal of a $20 million grant from the Common Fund of the National Institutes of Health (NIH) to researchers, including a team at UTHealth Houston.

23 Jan 2025

Study uncovers blood signatures linked to Sudden Infant Death Syndrome

New University of Virginia School of Medicine research revealing the fingerprints of Sudden Infant Death Syndrome within blood samples could open the door to simple tests to identify babies at risk.

22 Jan 2025

Study reveals biotin’s potential to mitigate manganese-induced brain damage

While manganese is an essential mineral involved in many bodily functions, both deficiency and excessive exposure can cause health issues.

21 Jan 2025

A new AI tool for unlocking the secrets of spatial multi-omics in cancer

A new artificial intelligence-powered tool called MISO (Multi-modal Spatial Omics) can detect cell-level characteristics of cancer by looking at data from extremely small pieces of tissue-some as small as 400 square micrometers, equivalent to the width of five human hairs.

16 Jan 2025