Metabolomics News and Research

Latest Metabolomics News and Research

What is the effect of maternal circulating amino acids on offspring birthweight?

Researchers examined the effect of serum levels of 20 amino acids in a mother during pregnancy on offspring birthweight in a two-sample summary data Mendelian randomization framework.

27 Feb 2023

Difference between human and mouse lung tumor cells explains the discrepancy in cancer drug results

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments.

24 Feb 2023

Researchers reveal the metabolic reactions upon activating Akt2 enzyme

Takeaki Ozawa and his team from the University of Tokyo reveal the metabolic reactions upon activating an enzyme called Akt2. In doing so, they reveal the inner workings of insulin-regulated metabolism.

21 Feb 2023

Major funding boost for research on neurodegenerative diseases

Brain Canada and the Canadian Institutes of Health Research congratulate Dr. Meaghan O'Reilly from Sunnybrook Research Institute and the University of Toronto as well as Dr. Liang Li based out of University of Alberta whose projects have been recommended for funding as part the 2022 European Union Joint Programme on Neurodegenerative Disease Research (JPND)'s initiative to find causes, develop cures and identify better ways to care for people with Alzheimer's, Parkinson's, Huntington's and other neurodegenerative diseases more rapidly.

16 Feb 2023

Study elucidates how cannabidiol reduces seizures in treatment-resistant pediatric epilepsy

A study reveals a previously unknown way in which cannabidiol (CBD), a substance found in cannabis, reduces seizures in many treatment-resistant forms of pediatric epilepsy.

13 Feb 2023

Multi-omics approach uncovers gut microbiome-host interactions in myalgic encephalomyelitis/chronic fatigue syndrome patients

Researchers performed a multi-omics investigation of gut microbiome-host interactions and plasma metabolomics among myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients.

10 Feb 2023

Research reveals differences in the gut microbiomes of people with ME/CFS

The study was led by scientists at the Center for Infection and Immunity (CII) at Columbia University Mailman School of Public Health, as part of the Center for Solutions for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, an inter-disciplinary, inter-institutional research group dedicated to understanding the biology of the disease in order to develop effective means to diagnose, treat and prevent it.

8 Feb 2023

Targeting a single enzyme can kill prostate cancer cells

For the first time, researchers have discovered that prostate cancer can be killed by targeting a single enzyme, called PI5P4Kα.

3 Feb 2023

Research offers hope for patients affected by rare, hereditary metabolic disease

Methylmalonic aciduria (MMA) is a metabolic disorder that affects approximately one in 90,000 newborns; both parents must carry a genetic predisposition to the disease.

26 Jan 2023

Study shows spatial organization in tumor cells

Researchers investigated whether the observed tumor cellular heterogeneity and architecture result from stochastic and chaotic events, or whether there is more coordination in the histopathological chaos of cancer.

24 Jan 2023

Are dysregulated metabolism and inflammation contributing factors to the ongoing symptoms in long-term COVID-19 syndrome patients?

Researchers reported that dysregulation in energy metabolism and inflammation could contribute to long-term COVID-19 syndrome.

19 Jan 2023

Researchers identify plasma metabolomic markers for the Mediterranean diet among pregnant women

A recent study identifies blood metabolomic markers and metabolite panels linked to the Mediterranean diet in pregnant women.

17 Jan 2023

Chemicals accumulated in the vagina may contribute to spontaneous preterm birth

Chemicals that accumulate in the vagina, potentially originating from personal care products, may contribute to spontaneous preterm birth, according to a new study by researchers at Columbia University Vagelos College of Physicians and Surgeons.

13 Jan 2023

Valuable tool reveals the connections between gut microbes and the brain

In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gut–brain axis.

13 Jan 2023

New cooling strategy could prevent the growth of glioblastoma

Cooling brain tumor cells to stop them from dividing without killing healthy cells extended the survival of glioblastoma (GBM) animal models dramatically in a study led by a UT Southwestern resident.

12 Jan 2023

Does the Mediterranean diet improve cognition?

A recent study looked at the metabolite output in people on an MD and the associations between this profile and the cognitive performance in this group.

9 Jan 2023

Early intervention key to managing diabetes, cardiorenal, and metabolic diseases

A panel of US-based experts in cardiology, nephrology, endocrinology, and primary care has prepared specific recommendations for early identification and intervention in obesity, diabetes, and other cardiorenal and metabolic diseases. A detailed report on recommended strategies has been published in the Journal of Diabetes and its Complications.

4 Jan 2023

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Researchers used a multi-omics approach to profile the gut microbiomes and metabolomes of mothers and infants to determine the vertical and horizontal transmission of bacterial species and strains as well as individual genes and understand the dynamics of the gut microbiome assembly that shape the development of the infant before and after birth.

29 Dec 2022

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

In a new study, researchers observed that coronavirus disease 2019 (COVID-19) progression and inflammatory responses are associated with changes in the metabolome and microbiome.

8 Dec 2022

Research project obtains nearly seven million to study factors that affect human immune system in early life

The first few months and years of life are crucial to the development of the human immune system. This is an important phase as the immune system can define which diseases individuals might develop later in life.

2 Dec 2022