Motor Neurone Disease

The motor neurone diseases (or motor neuron diseases) (MND) are a group of neurological disorders that selectively affect motor neurones, the cells that control voluntary muscle activity including speaking, walking, breathing, swallowing and general movement of the body.

What is Motor Neurone Disease?

Motor neurone disease is a rare condition of the nervous system that leads to loss of muscle control. The disease leads to progressive weakness, muscle wastage and eventually disability.

Motor Neurone Disease Causes

Motor Neurone Disease Diagnosis

Motor Neurone Disease Symptoms

Motor Neurone Disease Epidemiology

Motor Neurone Disease Etymology

Motor Neurone Disease Pathophysiology

Motor Neurone Disease Prognosis

Motor Neurone Disease Treatment

Motor Neurone Disease Complications

Motor Neuron Disease: Can Dietary Supplements Help?

Types of Motor Neuron Disease and Their Causes

Latest Motor Neurone Disease News and Research

Potential new treatment for motor neurone disease shows promising results

A potential new treatment for motor neurone disease (MND) developed by a company spun-out of The University of Queensland has produced successful results in a human clinical trial.

9 Dec 2024

UCL scientists receive £78 million funding boost to develop treatment for motor neurone disease

A funding boost of more than £78 million will help UCL scientists working to develop a potential treatment for motor neurone disease, for which there is currently no cure and which affects 5,000 people each year in the UK.

14 Nov 2024

New drug shows promise for motor neurone disease treatment

A pioneering study published in the International Journal of Molecular Sciences by researchers at Durham University has revealed promising results for a new treatment targeting motor neurone disease (MND).

22 Oct 2024

New technique reveals abnormalities in motor neurone disease

Pathological abnormalities associated with motor neurone disease have been identified using a new technique developed at the University of Birmingham.

8 Aug 2024

Motor neurone disease research receives major boost through new data catalyst initiative

Research into the life-shortening neurological condition motor neurone disease (MND) will receive a major boost through the formation of a new data catalyst led by Health Data Research UK (HDR UK) and Dementia Platforms UK (DPUK).

29 Jul 2024

Research shows the ability of proteins to predict onset of many diverse diseases

Research on thousands of proteins measured from a drop of blood demonstrates the ability of proteins to predict the onset of many diverse diseases.

22 Jul 2024

Concussion history in rugby players linked to higher levels of neurodegenerative disease biomarkers

Retired rugby players who have suffered multiple concussions have higher levels of certain proteins in their blood, which may make them more prone to developing diseases such as motor neurone disease (MND), according to a new study.

17 Jul 2024

Revolutionizing treatment for neurological conditions with 3D printed surgical implants

Clever bio-inks that sit inside the human body and restore damaged neurons could cure a whole swathe of diseases in the next 20 years: conditions that have baffled scientists and clinicians for centuries.

6 May 2024

Scientists uncover key protein aggregation in frontotemporal dementia

Most neurodegenerative diseases, including dementias, involve proteins aggregating into filaments called amyloids.

6 Dec 2023

Hundreds of proteins and mRNA molecules mislocated in ALS nerve cells

Researchers at the Francis Crick Institute and UCL have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS).

21 Jul 2023

Nerve cell discovery may improve treatment options for patients with neurodegenerative diseases

A discovery that may improve treatment options for patients with neurodegenerative diseases has been made by scientists at King's College London and the University of Bath in the UK.

16 Nov 2022

Over £800 million to support improved healthcare delivery and breakthroughs in new treatments

Patients up and down the country are set to benefit from innovative new treatments and improved delivery of health and care services following significant funding to support ground-breaking experimental medicine research and advance the UK's response to patient safety challenges.

14 Oct 2022

Clinical suite to help unlock the mysteries of neurological disorders

A clinical suite at a University of Queensland health research facility is ready to help unlock the mysteries of neurological conditions experienced by one billion people worldwide.

26 Sep 2022

New genetically-targeted MND therapy could be a turning point for patient care

Scientists believe a new genetically-targeted therapy to treat motor neurone disease (MND) could be a turning point for patient care, after the results of a Phase 3 clinical trial showed significant physical benefits for patients after 12 months.

21 Sep 2022

Repurposed drug shows promise as potential new treatment for motor neuron disease

A drug typically used to treat enlarged prostates and high blood pressure has shown promise as a potential new therapy for motor neuron disease (MND), according to a new study.

11 Aug 2022

LifeArc and UK DRI launch new partnership to accelerate development of new treatments for dementia

LifeArc and the UK Dementia Research Institute (UK DRI) have today launched a new partnership to accelerate development of new diagnostic tests, treatments, and devices from scientific research discoveries to benefit people with dementia, which around 900,000 people in the UK are living with.

15 Jun 2022

3D-printed bracelet may allow people with hand-impairment to use computers, play video games

People who lack the ability to use their hands from conditions like motor neurone disease and cerebral palsy may one day be able to play video games that require a handheld controller through the use of acustomisable, wearable 3D printed bracelet.

4 May 2022

New Alzheimer’s disease hypothesis could open up diagnosis or treatment possibilities

Alzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brain, newly published research argues.

8 Apr 2022

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

A pioneering new study led by UCL and National Institutes of Health (NIH) scientists has revealed, for the first time, why a common genetic variant worsens disease outcomes for people with the devastating adult-onset neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

24 Feb 2022

Machine learning model identifies new risk genes for motor neurone disease

Scientists have developed a new machine learning model for the discovery of genetic risk factors for diseases such as Motor Neurone Disease (MND).

18 Jan 2022

Motor Neurone Disease

Overview

Motor Neurone Disease Causes

Motor Neurone Disease Diagnosis

Motor Neurone Disease Symptoms

Feature Articles

Motor Neurone Disease Epidemiology

Motor Neurone Disease Etymology

Motor Neurone Disease Pathophysiology

Motor Neurone Disease Prognosis

Motor Neurone Disease Treatment

Motor Neurone Disease Complications

Motor Neuron Disease: Can Dietary Supplements Help?

Types of Motor Neuron Disease and Their Causes

Latest Motor Neurone Disease News and Research

Potential new treatment for motor neurone disease shows promising results

UCL scientists receive £78 million funding boost to develop treatment for motor neurone disease

New drug shows promise for motor neurone disease treatment

New technique reveals abnormalities in motor neurone disease

Motor neurone disease research receives major boost through new data catalyst initiative

Research shows the ability of proteins to predict onset of many diverse diseases

Concussion history in rugby players linked to higher levels of neurodegenerative disease biomarkers

Revolutionizing treatment for neurological conditions with 3D printed surgical implants

Scientists uncover key protein aggregation in frontotemporal dementia

Hundreds of proteins and mRNA molecules mislocated in ALS nerve cells

Nerve cell discovery may improve treatment options for patients with neurodegenerative diseases

Over £800 million to support improved healthcare delivery and breakthroughs in new treatments

Clinical suite to help unlock the mysteries of neurological disorders

New genetically-targeted MND therapy could be a turning point for patient care

Repurposed drug shows promise as potential new treatment for motor neuron disease

LifeArc and UK DRI launch new partnership to accelerate development of new treatments for dementia

3D-printed bracelet may allow people with hand-impairment to use computers, play video games

New Alzheimer’s disease hypothesis could open up diagnosis or treatment possibilities

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

Machine learning model identifies new risk genes for motor neurone disease

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Motor Neurone Disease

Overview

Feature Articles

Motor Neurone Disease Epidemiology

Motor Neurone Disease Etymology

Motor Neurone Disease Pathophysiology

Motor Neurone Disease Prognosis

Motor Neurone Disease Treatment

Motor Neurone Disease Complications

Motor Neuron Disease: Can Dietary Supplements Help?

Types of Motor Neuron Disease and Their Causes

Latest Motor Neurone Disease News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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