Mpox News and Research

Latest Mpox News and Research

Bioinformatics analysis of monkeypox virus-host cell interactions

A recent study posted to the bioRxiv* preprint server reported the interaction between monkeypox and human cells. Molecular sequences were screened to identify differentially expressed genes (DEGs) and their associated signal pathway, expression regulation, and metabolic pathways.

18 Oct 2022

On-site ultrasensitive monkeypox viral testing using CRISPR/Cas12a

In a new study posted to the medRxiv* preprint server, researchers in China developed an MPXV assay combining clustered regularly interspaced short palindromic repeats and CRISPR-associated protein (CRISPR/Cas) and recombinase-aided amplification (RAA) for the first time.

18 Oct 2022

Scientists detect monkeypox virus in the testes of macaques during acute infection

For the first time, scientists have detected monkeypox virus in the testes of macaques during the acute phase of infection, according to research published online today in the journal Nature Microbiology.

17 Oct 2022

Clinical trial to evaluate antiviral drug for monkeypox begins in the Democratic Republic of the Congo

A clinical trial to evaluate the antiviral drug tecovirimat, also known as TPOXX, in adults and children with monkeypox has begun in the Democratic Republic of the Congo (DRC).

12 Oct 2022

Mismatches in the primer and probe sequences of current Monkeypox virus diagnostic assays require rectification to improve detection accuracy

Researchers analyzed the primer and probe sequences of the United States Centers for Disease Control and Prevention (CDC) recommended monkeypox virus (MPXV) generic real-time polymerase chain reaction (PCR) assays.

11 Oct 2022

The role of wastewater surveillance for monitoring monkeypox

A new study reviews the advantages and current challenges associated with wastewater-based surveillance of MPXV.

10 Oct 2022

What is the impact of monkeypox infection on the hemostatic system?

In a recent study, researchers determined if monkeypox (MPX) infection affected the hemostatic system like that observed in coronavirus disease 2019 (COVID-19).

6 Oct 2022

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

In a new study, researchers determined the 1.8-Å resolution crystal structure of the H1 dual specific phosphatase (DSP) of monkeypox virus (MPXV) that is crucial for viral replication, making it an attractive antiviral target.

5 Oct 2022

Myocarditis may be attributable to monkeypox infection

A new study published in Emerging Infectious Diseases found that myocardial infiltration could cause myocarditis during monkeypox virus infection.

5 Oct 2022

Study finds the majority of post-vaccination monkeypox infections occur within 2 weeks of receiving the first dose of MVA-BN

Researchers described the human monkeypox virus infection after vaccination with the modified Vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine.

5 Oct 2022

Small antiviral molecules termed assembly modulators show therapeutic efficacy against cancer

In a new study, researchers evaluated the anti-cancer therapeutic efficacy of two structurally-unrelated small molecules, PAV-617 and PAV-951.

4 Oct 2022

Study attributes increased transmissibility of Monkeypox Clade IIb to genomic accordions

In a new study, researchers performed a genomic study of confirmed Monkeypox virus (MPXV) cases diagnosed in Spain between 18 May and 14 July 2022.

4 Oct 2022

The likelihood of reverse zoonotic transmission of the monkeypox virus to pet animals

Researchers performed assessed the risk of reverse transmission MPXV of clade IIb or the West African clade from humans to animals in the UK.

3 Oct 2022

French study reports growing evidence of sexual activity-linked transmission of monkeypox

In a new study, researchers described patients with monkeypox virus (MPXV) infection.

3 Oct 2022

Best-science guidance lost battle early during COVID-19 pandemic

Researchers used a mathematical model to depict how the general public drifted away from best-science guidance early during the COVID-19 pandemic.

3 Oct 2022

Structural analysis of monkeypox virus to guide the development of broad antiviral agents

In a new study, researchers explored the crystalline structure of the monkeypox (MPX) virus (MPXV) and the complex of VP39, a 2′-O-RNA methyltransferase (MTase) and sinefungin, a pan-MTase inhibitor.

30 Sep 2022

The management of monkeypox during pregnancy

In a recent correspondence, the authors responded to and clarified some of the contentions discussed in a letter to the editor about their August 2022 article on forecasting the risks of monkeypox in pregnant women.

30 Sep 2022

DNA metagenomic analyses of clinical samples from Monkeypox virus-infected individuals

Researchers analyzed genomic sequences of MPXV obtained from 18 patients who contracted MPXV infection between June and July 2022.

30 Sep 2022

Pluripotent bat stem cells as a model to study novel viruses

Researchers generate induced pluripotent stem cells from bats using to establish bats as a novel in vivo model study species.

29 Sep 2022

KHN’s ‘What the Health?’: On government spending, Congress decides not to decide

Congress is supposed to complete its annual appropriations bills before the start of the fiscal year on Oct. 1.

29 Sep 2022

Mpox News and Research

Latest Mpox News and Research

Bioinformatics analysis of monkeypox virus-host cell interactions

On-site ultrasensitive monkeypox viral testing using CRISPR/Cas12a

Scientists detect monkeypox virus in the testes of macaques during acute infection

Clinical trial to evaluate antiviral drug for monkeypox begins in the Democratic Republic of the Congo

Mismatches in the primer and probe sequences of current Monkeypox virus diagnostic assays require rectification to improve detection accuracy

The role of wastewater surveillance for monitoring monkeypox

What is the impact of monkeypox infection on the hemostatic system?

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

Myocarditis may be attributable to monkeypox infection

Study finds the majority of post-vaccination monkeypox infections occur within 2 weeks of receiving the first dose of MVA-BN

Small antiviral molecules termed assembly modulators show therapeutic efficacy against cancer

Study attributes increased transmissibility of Monkeypox Clade IIb to genomic accordions

The likelihood of reverse zoonotic transmission of the monkeypox virus to pet animals

French study reports growing evidence of sexual activity-linked transmission of monkeypox

Best-science guidance lost battle early during COVID-19 pandemic

Structural analysis of monkeypox virus to guide the development of broad antiviral agents

The management of monkeypox during pregnancy

DNA metagenomic analyses of clinical samples from Monkeypox virus-infected individuals

Pluripotent bat stem cells as a model to study novel viruses

KHN’s ‘What the Health?’: On government spending, Congress decides not to decide

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Mpox News and Research

Latest Mpox News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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