Nervous System News and Research

Latest Nervous System News and Research

Study finds disparities in access to memory care clinics

Black people and people living in less affluent neighborhoods-;areas with higher poverty levels and fewer educational and employment opportunities-; may be less likely to be seen at a memory care clinic compared to white people and people living in neighborhoods with fewer disadvantages, according to new research published in the August 2, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

2 Aug 2023

New drug shows promise for treating chronic neuropathic pain

A non-opioid designer molecule for treating chronic neuropathic pain by calming hyperactive pain-sensing neurons in the peripheral nervous system has had promising results in a preclinical study conducted by researchers at Weill Cornell Medicine and the Burke Neurological Institute.

2 Aug 2023

Insilico Medicine uses AI to discover novel SIK2 inhibitors

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has achieved a significant breakthrough in the application of multiple generative AI models and AlphaFold structures for drug discovery.

2 Aug 2023

Can vitamin D have positive effects on reducing cortical pathology, oxidative stress, and neurofilament light chain serum levels?

Researchers use an established murine model of cortical inflammatory demyelination to investigate the effects of vitamin D.

2 Aug 2023

Sex differences in depression: Including transgender and intersex populations in mental health research

In 2016, recognizing that lack of research in female animals was hampering the success of treatments for mood disorders, the National Institutes of Health (NIH) changed its policy for basic research to include sex as a biological variable for basic research, a move that triggered an explosion of research into sex differences.

1 Aug 2023

Investigating the neurological effects of SARS-CoV-2: anosmia and neuroinvasion as separate phenomena

A group of researchers investigated the neurotropic potential of SARS-CoV-2 and its variants by studying their ability to invade the brain through the olfactory pathway in hamsters.

1 Aug 2023

RSV vaccines for older adults: 2023 ACIP recommendations

A recent report published in Morbidity and Mortality Weekly Report provided clinical guidance on Respiratory syncytial virus (RSV) vaccines for adults ≥60 years.

1 Aug 2023

Novel tool uncovers new cell types in the visual system of flies

New York University researchers have discovered new cell types in the visual system of flies, made possible by their creation of a tool that finds and labels neurons during development.

31 Jul 2023

NIH launches and opens enrollment for phase 2 clinical trials to evaluate long COVID treatments

Today, the National Institutes of Health launched and is opening enrollment for phase 2 clinical trials that will evaluate at least four potential treatments for long COVID, with additional clinical trials to test at least seven more treatments expected in the coming months.

31 Jul 2023

Trial evaluates purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder

Researchers investigated the safety and pharmacokinetics of JNJ-54175446 in a double-blind, multicenter, randomized controlled trial (RCT).

31 Jul 2023

Novel vaccine targets inflamed brain cells in Alzheimer's to modify the course of disease

A novel vaccine that targets inflamed brain cells associated with Alzheimer's disease may hold the key to potentially preventing or modifying the course of the disease, according to preliminary research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2023.

31 Jul 2023

Researchers discover new spiroindolin-1,2-diazepine derivatives with anti-Alzheimer therapeutic potential

In a recent study, researchers designed substituted spiro indolin-1,2-diazepine derivatives '5a–v' with cholinesterase inhibitory activities as anti-Alzheimer's disease agents.

31 Jul 2023

Scientists map 3D structure of kappa opioid receptor

Opioids remain the most potent and effective pain relievers in medicine, but they're also among the most addictive drugs that can halt a person's ability to breathe during an overdose -; which can be deadly.

27 Jul 2023

The role of diet in the management of retinal vein occlusion

Researchers investigate the potential impact of dietary habits on retinal vein occlusion.

27 Jul 2023

The role of vasomotor reactivity in COVID-19 patients

Researchers searched and collated the most relevant published literature on cerebral hemodynamic changes in COVID-19 patients.

27 Jul 2023

People with Alzheimer's risk gene may lose ability to detect odors earlier

People who carry the gene variant associated with the strongest risk for Alzheimer's disease may lose their ability to detect odors earlier than people who do not carry the gene variant, which may be an early sign of future memory and thinking problems, according to a study published in the July 26, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

26 Jul 2023

Experts weigh benefits and risks of new Alzheimer's disease therapies

New therapies for early Alzheimer's disease, monoclonal antibodies that remove amyloid-β plaques in the brain, are bringing hope to people whose lives have been affected by the disease.

26 Jul 2023

Kundalini yoga may be beneficial for older women with Alzheimer's risk factors

Kundalini yoga, a form of yoga that focuses on breathing, meditation, and mental visualization, appeared beneficial for older women who had risk factors for Alzheimer's disease and concerns about episodes of memory decline, according to a UCLA Health study.

26 Jul 2023

Researchers create "synthetic embryos" from bovine pluripotent stem cells

An article published in the journal Cell Stem Cell describes the first scientific study to develop blastoids – "synthetic embryos", as they were initially (and incorrectly) called – from bovine pluripotent stem cells (PSCs).

26 Jul 2023

Newly identified brain cell type may play role in neuropsychiatric disorders

A University of California, Irvine-led team of researchers working at the Center for Neural Circuit Mapping find links between brain disorders and dysfunction of newly identified inhibitory brain cell types.

25 Jul 2023