Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Survivors of childhood cancers hospitalized more often many years after cancer treatment

Survivors of childhood cancers were hospitalized more often and for longer durations because of blood disorders and other problems, many years after cancer treatment was completed, compared with the general population, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

13 Jun 2014

International partnership of charities funds first immunotherapy clinical trial for children with neuroblastoma

Solving Kids' Cancer, the Neuroblastoma Children's Cancer Alliance (NCCA UK), and Joining Against Cancer in Kids (J-A-C-K) awarded its first grant through their INBRACED (International Neuroblastoma Research and Collaboration for Effective Delivery) initiative, which aims to improve access of promising clinical trials for children with high-risk neuroblastoma in North America, the UK and in Europe.

23 May 2014

Drugs that boost protein's production in neurons could help ward off Alzheimer's disease

In surprise findings, scientists at The Scripps Research Institute (TSRI) have discovered that a protein with a propensity to form harmful aggregates in the body when produced in the liver protects against Alzheimer's disease aggregates when it is produced in the brain.

22 May 2014

Nationwide Children's Hospital offers Meta-iodobenzylguanidine therapy for neuroblastoma

Meta-iodobenzylguanidine (MIBG) therapy is now offered by Hematology/Oncology/Blood and Marrow Transplant at Nationwide Children's Hospital. Patients with neuroblastoma who qualify for treatment with MIBG therapy can be treated in this new facility, with round-the-clock supervision by specially trained staff through video and audio monitoring.

21 May 2014

CHOP oncologist receives Lifetime Achievement Award at ANRA association's international meeting

The Advances in Neuroblastoma Research Association (ANRA) is conferring its highest honor on pediatric oncologist Garrett M. Brodeur, M.D., of the Cancer Center at The Children's Hospital of Philadelphia (CHOP).

16 May 2014

Experimental antibody temporarily halts progression of neuroblastoma in children

Tumors shrank or disappeared and disease progression was temporarily halted in 15 children with advanced neuroblastoma enrolled in a safety study of an experimental antibody produced at St. Jude Children's Research Hospital.

9 May 2014

Comer Children's Hospital offers high-dose radiation therapy for relapsed neuroblastoma

The University of Chicago Medicine Comer Children's Hospital has become the first in Illinois to offer pioneering, targeted, high-dose, intravenous radiation therapy for relapsed neuroblastoma and other difficult-to-treat cancers.

9 May 2014

Novogen partners with Genea Biocells to accelerate testing for neurodegenerative diseases

Novogen Limited, an oncology drug development company, today announced a collaboration with Australian company, Genea Biocells, to accelerate testing of their super-benzopyran (SBP) drugs for degenerative diseases of the nervous system and muscles.

5 May 2014

Study shows R9-caPep compound blocks PCNA actions in neuroblastoma cells

Neuroblastoma is one of the deadliest childhood cancers, accounting for 15 percent of pediatric cancer deaths. For patients with high-risk neuroblastomas, the five-year survival rate is 40 to 50 percent even with the most rigorous treatments available today.

17 Apr 2014

Research suggests NEDD9 scaffolding protein activates oncogenic signaling pathways in cancer cells, encourages metastases

Researchers from Fox Chase Cancer Center have shown that NEDD9, a scaffolding protein responsible for regulating signaling pathways in the cell, promotes the growth and spread of epithelial ovarian cancer.

7 Apr 2014

Helium ion radiotherapy provides hope for improved, accurate radiation treatment for young cancer patients

For the first time, researchers have been able to demonstrate that the use of helium ions in radiation therapy could provide accurate treatment to tumours while helping to spare healthy organs.

7 Apr 2014

Novartis to present early stage data on 19 investigational compounds at AACR annual meeting

Novartis announced today that early stage data on 19 investigational compounds in its oncology pipeline will be presented at the annual meeting of the American Association of Cancer Research, April 5-9, 2014 in San Diego, CA.

4 Apr 2014

Researchers unravel function of proteins involved in cell metabolism

UCPs or uncoupling proteins are present in mitochondria, the powerhouse of each cell in the body. The functions of most of the five known UCPs remain mysterious (UCP2-UCP5), whereby only the distinct function for UCP1 has thus far been discovered.

5 Mar 2014

Scientists unveil role of microRNAs in regulating neuroblastoma, pointing to new therapeutic possibilities

Neuroblastoma is one of the most common and lethal types of childhood cancers. In a paper published online today in OncoTarget, a researcher at the University of Texas Health Science Center at San Antonio unveils the important role of microRNAs in regulating neuroblastoma development, pointing to new therapeutic possibilities.

3 Mar 2014

Professor receives ALSF grant to develop cancer vaccine technology that help children to have healthy life

In 2004, a form of cancer known as neuroblastoma claimed the life of Alexandra (Alex) Scott, a little girl who gained national attention for using her lemonade stand to raise money for cancer research.

8 Jan 2014

Memorial Sloan-Kettering to use Sutro's cell-free protein synthesis technology to produce bispecific antibodies

Sutro Biopharma, a biopharmaceutical company developing a new generation of protein therapeutics, including next-generation antibody drug conjugates and bispecific antibodies, today announced that it has entered into a collaboration agreement with Memorial Sloan-Kettering Cancer Center to use Sutro's proprietary cell-free protein synthesis technology to produce bispecific antibodies that were discovered by Memorial Sloan-Kettering for the treatment of neuroblastoma in children.

7 Jan 2014

Cancer survival rates still vary widely between European countries

Cancer survival still varies widely between European countries despite major improvements in cancer diagnosis and treatment during the first decade of the 21st century, according to the latest EUROCARE-5 reports covering over 50% of the adult and 77% of the childhood population of Europe.

6 Dec 2013

Stanford researchers receive $1.37M grant to study on immune systems of pediatric cancer patients

Kathleen Sakamoto, MD, PhD, and Irving Weissman, MD, of the Stanford University School of Medicine and Lucile Packard Children's Hospital, have received a $1.37 million grant from CureSearch for Children's Cancer to research the effects of an antibody that has been shown to be effective against human cancers in animal models.

5 Nov 2013

New small-molecule inhibitor shows promising results in drug-resistant melanoma, breast cancer

LEE011, a small-molecule inhibitor of cyclin-dependent kinases (CDK) 4/6 being developed by Novartis Oncology, showed promising results in drug-resistant melanoma and drug-resistant breast cancer when tested in combination with other targeted therapies, and based on these preclinical results, several phase I clinical trials were launched recently, according to results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held October 19-23.

21 Oct 2013

Scientists to combine NK cell therapy with immunocytokine to target childhood cancer

Researchers have made rapid advances in understanding how to manipulate the immune system safely to destroy cancer cells. Adoptive transfer of haploidentical natural killer cells has shown promise as a treatment option to target and kill cancer cells in a less toxic way than conventional therapies. Now for the first time, scientists will combine NK cell therapy with an immunocytokine to target children with relapsed/refractory disease including those with bulky tumors.

11 Oct 2013

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Survivors of childhood cancers hospitalized more often many years after cancer treatment

International partnership of charities funds first immunotherapy clinical trial for children with neuroblastoma

Drugs that boost protein's production in neurons could help ward off Alzheimer's disease

Nationwide Children's Hospital offers Meta-iodobenzylguanidine therapy for neuroblastoma

CHOP oncologist receives Lifetime Achievement Award at ANRA association's international meeting

Experimental antibody temporarily halts progression of neuroblastoma in children

Comer Children's Hospital offers high-dose radiation therapy for relapsed neuroblastoma

Novogen partners with Genea Biocells to accelerate testing for neurodegenerative diseases

Study shows R9-caPep compound blocks PCNA actions in neuroblastoma cells

Research suggests NEDD9 scaffolding protein activates oncogenic signaling pathways in cancer cells, encourages metastases

Helium ion radiotherapy provides hope for improved, accurate radiation treatment for young cancer patients

Novartis to present early stage data on 19 investigational compounds at AACR annual meeting

Researchers unravel function of proteins involved in cell metabolism

Scientists unveil role of microRNAs in regulating neuroblastoma, pointing to new therapeutic possibilities

Professor receives ALSF grant to develop cancer vaccine technology that help children to have healthy life

Memorial Sloan-Kettering to use Sutro's cell-free protein synthesis technology to produce bispecific antibodies

Cancer survival rates still vary widely between European countries

Stanford researchers receive $1.37M grant to study on immune systems of pediatric cancer patients

New small-molecule inhibitor shows promising results in drug-resistant melanoma, breast cancer

Scientists to combine NK cell therapy with immunocytokine to target childhood cancer

Innovation in neuroscience drug discovery - eBook eBook

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

The evolution of OCT for retinal imaging and disease intervention

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Innovation in neuroscience drug discovery - eBook eBook

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

The evolution of OCT for retinal imaging and disease intervention

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